Mariam Mohagheghi
Livermore,CA
Summary
Organized and dependable biomedical scientist successful at managing multiple priorities with a positive attitude. Proficient in molecular biology, protein production, and cell culture techniques. Demonstrated ability to lead research projects, collaborate effectively, and present findings at research. Committed to advancing biomedical research and contributing to peer-reviewed publications.
Overview
3
3
years of professional experience
Work History
Academic Graduate Appointment
Lawrence Livermore National Laboratory
04.2022 - Current
- Managed multiple Chlamydia vaccine studies, overseeing production, quality control, and characterization of antigen candidates.
- Collaborated closely with new Principal Investigator (PI) to design and establish Chlamydomonas Reinhardtii culture protocols. Optimized chloroplast extraction methods for downstream analyses. Contributed to successful encapsulation and expression for target gene expression.
- Design and validate primers using qPCR for diagnostic applications in human health.
- Cultivated professional writing and presentation skills through participation in conferences and co-authorships of scientific papers.
Neuroscience and Neuroimmunology Research Intern
University Of Nebraska Medical Center
08.2021 - 02.2022
- Selected for fully funded research fellowship sponsored by the Department of Pharmacology and Experimental Neuroscience.
- Lead the Mechanistic Study of NeuroAIDS and interplay of various drugs of abuse project. Acquired proficiency in diverse range of experimental techniques and skillset within the initial months of the internship, enable effective development and investigation of scientific inquiries.
- Enrolled in first-year Neuroscience graduate coursework to enhance theoretical knowledge and its practical applications in conjunction with hands-on research activities.
Research Analyst
Creighton University School Of Medicine
04.2021 - 08.2021
- Contributed to the laboratory’s mission of developing preventative and therapeutic treatments for UV-induced skin carcinogenesis.
- Focused on the formulation of ROS-scavenging enzymes within the biodegradable and non-toxic nanoparticle Pro-NP, strategically designed for effective epidermal penetration.
- Provided valuable support to multiple graduate students, enhancing collaborative research efforts within the team.
- Successfully completed my Master of Science capstone project, conducting thorough analysis of sex-linked differences observed in multiple mice studies following topical Pro-NP application.
- Invited to extend involvement into the summer, highlighting the quality and impact of my contributions as a dedicated master’s student.
Education
Master of Science - Medical Sciences
Creighton University School of Medicine
Omaha, NE08.2021
Bachelor of Science - Biochemistry
University of New Mexico
Albuquerque, NM05.2020
Skills
- Nucleic acid isolation: RNA, DNA, Qiagen kit
- Polymerase chain reaction (RT-qPCR, double droplet, two step)
- Protein expression and purification systems: E Coli, cell-free, FPLC AKTA, affinity
- Protein characterization: SDS-PAGE, gel electrophoresis, Western blot
- Cell culture: aseptic techniques, cell line maintenance, transfection/transduction, cell viability assays, cell-based assays (ELISA, FACs)
Accomplishments
- ·M. Mohagheghi et al., Cell-free screening and production of chlamydial membrane-bound proteins. Expected publication: Early 2024.
- Formal Presentation: Developing a cell-free microfluidics-based screening platform for Chlamydomonas reinhardtii chloroplasts.
- Formal presentation: Cell-free screening and production of Chlamydial membrane-bound proteins. STI & HIV 2023 World Congress. July 2023.
Timeline
Academic Graduate Appointment
Lawrence Livermore National Laboratory
04.2022 - Current
Neuroscience and Neuroimmunology Research Intern
University Of Nebraska Medical Center
08.2021 - 02.2022
Research Analyst
Creighton University School Of Medicine
04.2021 - 08.2021
Master of Science - Medical Sciences
Creighton University School of Medicine
Bachelor of Science - Biochemistry
University of New Mexico
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