Marielle Summers
Cell Therapy Scientist
Seattle,WA
Summary
Organized and dependable scientist successful at managing multiple priorities with a positive attitude. Fast learner with excellent communication skills ready to take on added responsibilities to drive team goals and drive IND/ BLA enabling projects.
Overview
9
9
years of professional experience
Work History
Senior Associate Scientist, Allogeneic Platform
Bristol Myers Squibb
Seattle, WA
02.2022 - Current
- Serve as subject matter expert on several complex topics to advise cross functional teams and train new team members.
- Design and execute a series of experiments to generate a comprehensive data package for key decisions relating to the Allogeneic Platform strategy.
- Develop novel technologies and protocols in support of product development from proof of concept to clinical manufacturing.
- Work with cross functional teams to meet key milestones and maintain project timelines.
- Develop and maintain SOPs, electronic batch records and critical equipment
- Mentor, advise and train junior members of our team
- Managed an intern: set up their in depth training and developed their knowledge of cell therapy, mentored and advised on their experiments and presentations
Associate Scientist, Allogeneic Platform
Bristol Myers Squibb
Seattle, WA
08.2021 - 02.2022
- Design and execute complex and repeated end to end platform development experiments
- Analyze and present complex data sets, provide recommendations for procedural changes
- Became a subject matter expert on eletctroporation and gene editing using CRISPR Cas9 and AAVs
- Train and mentor new staff on cell therapy laboratory techniques
- Managed a rotational employee for 6 months: trained and mentored on aseptic processing and cell culture, provided feedback and guidance
Assistant Scientist, Allogenic Platform
Bristol Myers Squibb
Seattle, WA
07.2020 - 08.2021
- Perform end to end cell therapy experiments using electronic lab notebooks
- Utilize statistical software (JMP, Excel) to analyze data and present results to larger teams
- Utilize proof of concept (POC), design of experiment (DOE) principles to design robust experiments
- Master T-Cell selection, activation, transduction, electroporation, expansion and harvest unit operations
- Demonstrate meticulous aseptic technique and maintain sterile culture
Clinical Manufacturing Associate, Cell Therapy
Juno Therapeutics Inc.
Bothell, WA
04.2018 - 07.2020
- Performed aseptic cell culture in Human T cells following cGMP procedures and Standard Operating Procedures with complete and thorough GDP
- Extensive aseptic practice handling human derived materials in BSL-2 containment areas, following proper gowning for ISO 5/7/8/9
- Write manufacturing operating procedures that are technically sound, promote effective and efficient operations, and comply with cGMP requirements
- Write and carry out deviation investigations, CAPAs and Change Controls
- Received Yellow Belt training for 5S projects and project management
Research Associate
UW Biofab
Seattle, WA
02.2014 - 03.2018
- Carry out primarily e. Coli and yeast cloning assays, from fragment and plasmid construction through transformation, cryopreservation and DNA extraction
- Develop and write procedures and protocols in an electronic record with programming staff
- Carry out test runs of new and updated procedures to validate the record and check for accuracy
- Design and maintain inventory system for critical reagents and labware
Education
Bachelor of Science - Chemistry, Psychology
University of Washington
Seattle, WA 05.2001 -
Skills
Project Management
Process Development
Data Analysis
Training and mentoring
Aseptic Cell Culture
Gene Editing
Electroporation
GMP Manufacturing
Technical Writing
Viral and Non Viral Gene Delivery
Group Presentations
Communication
Flow Cytometry/ FACS
Experimental Design
Timeline
Senior Associate Scientist, Allogeneic Platform
Bristol Myers Squibb
02.2022 - Current
Associate Scientist, Allogeneic Platform
Bristol Myers Squibb
08.2021 - 02.2022
Assistant Scientist, Allogenic Platform
Bristol Myers Squibb
07.2020 - 08.2021
Clinical Manufacturing Associate, Cell Therapy
Juno Therapeutics Inc.
04.2018 - 07.2020
Research Associate
UW Biofab
02.2014 - 03.2018
Bachelor of Science - Chemistry, Psychology
University of Washington
05.2001 -