Matthew Hull
Groton,MA
Summary
Responsive Manufacturing Technician with highly developed skills in Cell Culture and instrumentation troubleshooting. Sound knowledge of production operations. Well-versed in streamlining and optimizing processes to exceed customer expectations.
Overview
15
15
years of professional experience
Work History
AFLEX Team Lead
Watson Marlow
Devens, Massachusetts
07.2025 - 10.2025
- Fabricated industrial, food grade, and pharmaceutical hoses and fittings per customer specifications.
- Facilitated team meetings to address challenges, share updates, and enhance collaboration.
- Delegated daily tasks to optimize productivity across team members.
- Collaborated with management to implement new work procedures and policies.
Manufacturing Associate
Synkriom(Bristol Myers Squibb)
Devens, Massachusetts
08.2024 - 06.2025
- Cell culture operations in single-use, multiproduct clinical manufacturing suites.
- Set up, processing, troubleshooting and breakdown of single use cell culture bio-reactors.
- Documented production data accurately for tracking and reporting purposes.
- Followed standard operating procedures to guarantee product integrity consistently.
- Collaborated with team members to optimize workflow and minimize downtime.
Senior Manufacturing Technician
Sanofi
Framingham, MA
12.2022 - 10.2023
- Cell Culture operations from initial vial thaw to wave seed reactors for scale up to 200-liter production reactor.
- Daily sampling, manual cell counting for viability, drain down harvest and re-feed of reactor operations.
- Termination, tear down, CIP, SIP and subsequent rebuild of production reactors to continue uninterrupted harvest of unpurified bulk.
- Implemented lean manufacturing principles to reduce waste, improve quality, and maximize resource utilization.
- Evaluated equipment performance data against established benchmarks to identify areas for improvement or replacement needs.
Senior Manufacturing Associate
Pfizer
Andover, MA
12.2021 - 12.2022
- Exceeded daily production targets with consistent attention to detail and commitment to meeting deadlines in clinical manufacturing suite.
- Purification of harvested material into purified bulk solution using chromatography and UFDF filtration systems.
- Assembly, CIP, pressure hold, SIP and disassembly of applicable systems.
- Subject matter expert of sampling instrumentation and viral inactivation.
Senior Manufacturing Technician
TScan
Waltham, MA
06.2021 - 11.2021
- Operated and maintained production equipment for small scale T-cell therapies.
- Collaborated with cross-functional teams to enhance production processes.
- Assisted in troubleshooting equipment malfunctions to minimize downtime.
- Implemented best practices for cleanroom procedures and environmental controls.
- Documented manufacturing processes and compliance data for regulatory audits.
Manufacturing Supervisor
Moderna
Norwood, MA
08.2020 - 12.2020
- Supervised daily manufacturing operations to ensure product quality and safety.
- Coordinated team schedules to optimize workflow and resource allocation.
- Trained new employees on standard operating procedures and safety protocols.
Bio Process Specialist
Bristol-Myers Squibb
Devens, MA
05.2017 - 07.2020
- Effectively and efficiently, performed Cell Culture operations ranging from vial thaw, scale up from seed reactors to production and harvest, trouble shooting, batch record software, peripherals and SOPs.
- Subject matter expert for Cell Culture/Upstream analytical equipment including Nova Flex, ViCell, Cedex and integrity testers serving as point of contact for on-site PM's and calibrations.
- Effectively track and trend process automation systems (i.e,Delta V and Syncade Interactions, OSI/Pi Historian) for troubleshooting and mitigation of any on floor issues working collaboratively with engineering and automation.
- Engages in and supports culture of continuous improvement through ownership of initiatives for work processes, equipment functionality and safe work environment.
- Revises and creates process documents (SOPs), supports routine process investigations, batch record review, exception reports and deviation investigations.
- Collaborated closely with cross-functional teams, ensuring seamless integration of processes across departments.
Manufacturing Technician II
Shire
Lexington, MA
07.2012 - 05.2017
- Experienced operator in multi-product Cell Culture and Recovery/Capture suite.
- Qualified Trainer/Operator of Clarification, UF/DF, Chromatography, Aseptic Processing and multiple testing/measuring instruments within scope of operations.
- Author and editor of numerous Batch Records, SOPs and Deviations.
- Experienced in execution of Validation and Engineering Protocols.
- Involved in Safety Committee, Compliance Team, Spill Response Team, R&D groups.
- Increased overall productivity by training new technicians and providing ongoing support to team members.
Manufacturing Technician I
Shire HGT
Lexington, MA
06.2010 - 07.2012
- Integral part of validation and shakedown operation of equipment in Central Services department within new Human Genetic Therapies production plant.
- Operates Media, Buffer and Glass Wash equipment according to SOPs and cGMP standards.
- Maintains accuracy of form prep records, clean room environment, equipment maintenance and trouble shooting to comply with GMP guidelines.
- Performed routine equipment calibration to maintain consistent product quality and adherence to specifications.
Education
High School Diploma -
Acton Boxborough Regional High School
Acton, MA06-1990
Skills
- Equipment maintenance
- Cell culture operations
- Lean manufacturing
- Regulatory compliance
- Effective communication
- Problem solving
- Training and development
- Collaboration skills
- Conflict resolution
- Coaching and mentoring
Timeline
AFLEX Team Lead
Watson Marlow
07.2025 - 10.2025
Manufacturing Associate
Synkriom(Bristol Myers Squibb)
08.2024 - 06.2025
Senior Manufacturing Technician
Sanofi
12.2022 - 10.2023
Senior Manufacturing Associate
Pfizer
12.2021 - 12.2022
Senior Manufacturing Technician
TScan
06.2021 - 11.2021
Manufacturing Supervisor
Moderna
08.2020 - 12.2020
Bio Process Specialist
Bristol-Myers Squibb
05.2017 - 07.2020
Manufacturing Technician II
Shire
07.2012 - 05.2017
Manufacturing Technician I
Shire HGT
06.2010 - 07.2012
High School Diploma -
Acton Boxborough Regional High School