Maurizio Morri, PhD, EMBA

Results-driven Director of Genomics at ALTOS LABS with expertise in multi-omics techniques and machine learning applications. Successfully led the groundbreaking Tabula Sapiens project while enhancing genomic research capabilities through next-generation sequencing. Demonstrates strong leadership skills in managing cross-functional teams, driving strategic innovation, and advancing scientific research initiatives.

• Interstitial macrophages are a focus of viral takeover and inflammation in COVID-19 initiation in human lung., J Exp Med., 06/03/24, 10.1084/jem.20232192, 38597954
• An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome., Nat Commun., 03/11/24, 10.1038/s41467-024-46070-9, 38467625
• Single-cell transcriptomic analysis of corneal organoids during development., Stem Cell Reports., 12/12/23, 10.1016/j.stemcr.2023.10.022, 38039970
• Single-nuclei characterization of pervasive transcriptional signatures across organs in response to COVID-19., Elife., 10/13/23, 10.7554/eLife.81090, 37830426
• KRAS(G12D) drives lepidic adenocarcinoma through stem-cell reprogramming., Nature., 07/01/23, 10.1038/s41586-023-06324-w, 37468622
• Purification and functional characterization of novel human skeletal stem cell lineages., Nat Protoc., 07/01/23, 10.1038/s41596-023-00836-5, 37316563
• Purification and characterization of human neural stem and progenitor cells., Cell., 03/16/23, 10.1016/j.cell.2023.02.017, 36931245
• Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver., Elife., 01/31/23, 10.7554/eLife.82311, 36719070
• Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy., Nat Commun., 08/30/22, 10.1038/s41467022-32397-8, 36042219
• Machine-learning-optimized Cas12a barcoding enables the recovery of single-cell lineages and transcriptional profiles., Mol Cell., 08/18/22, 10.1016/j.molcel.2022.06.001, 35752172
• The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans., Science., 05/13/22, 10.1126/science.abl4896, 35549404
• Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets., Nat Comput Sci., 05/01/22, 10.1038/s43588-022-00251-y, 38177826
• Cell types of origin of the cell-free transcriptome., Nat Biotechnol., 06/01/22, 10.1038/s41587-021-01188-9, 35132263
• UPIC-M: Efficient and Scalable Preparation of Clonal Single Mutant Libraries for High-Throughput Protein Biochemistry., ACS Omega., 11/02/21, 10.1021/acsomega.1c04180, 34805683
• RNA splicing programs define tissue compartments and cell types at single-cell resolution., Elife., 09/13/21, 10.7554/eLife.70692, 34515025
• Aged skeletal stem cells generate an inflammatory degenerative niche., Nature., 09/01/21, 10.1038/s41586-021-03795-7, 34381212
• Distinct skeletal stem cell types orchestrate long bone skeletogenesis., Elife., 07/19/21, 10.7554/eLife.66063, 34280086
• Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration., Elife., 01/16/19, 10.7554/eLife.42093, 30648973
• Optical functionalization of human Class A orphan G-protein-coupled receptors., Nat Commun., 05/16/18, 10.1038/s41467-018-04342-1, 29769519