Ming Chen

In the Department of Single-Cell Sequencing

• Led the bioinformatics team within the single-cell department, overseeing project delivery, pipeline development, and specialized R&D tasks.
• Acted as the primary bioinformatics lead for collaborative projects, conducting single-cell RNA sequencing data analysis for aplastic anemia.
• Developed a novel algorithmic tool for defining cell types in single-cell transcriptomics data(https://github.com/Bio-MingChen/novoalgor).
• Designed and implemented a fully automated bioinformatics analysis pipeline, enabling end-to-end analysis without manual bioinformatics intervention.
• Contributed to multiple R&D initiatives and pipeline optimizations, resulting in over ten software copyrights and one granted patent.

In the Department of Human Disease Research

• Conducted and completed various projects and R&D tasks related to whole-exome sequencing (WES) and whole-genome sequencing (WGS).
• Established a somatic mutation analysis pipeline, enabling the detection and identification of clonal hematopoiesis of indeterminate potential (CHIP) mutations.
• Served as the primary bioinformatics analyst for a GWAS study on cleft lip and palate.
• Developed disease-specific reports and a comprehensive disease database.