Summary
Overview
Work History
Education
Skills
Accomplishments
Certification
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Research Publications
Co Curricular Achievements
Education Summary
Disclaimer
Affiliations
Additional Information
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Quote
Work Availability
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Timeline
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Mythili Srinivasan

Bellevue,Washington

Summary

To leverage my knowledge and skills in a dynamic organization to achieve organizational and professional goals. My objectives include conducting cutting-edge research, developing innovative drug candidates, optimizing drug utilization, and contributing to scientific publications to advance the pharmaceutical field and improve patient care and public health.

Dedicated and diligent scientific professional, currently in the final year and final semester of pursuing a PhD at Dr. Vishwanath Karad MIT-World Peace University in Pune, Maharashtra, Specializing in targeted breast cancer therapy through Novel Drug Delivery Systems (NDDS), I focus on Metallic Nanoparticle-Entrapped Polymeric Hydrogel Delivery of Withaferin-A. Possessing experience in diverse areas such as research proposal and protocol drafting, scientific writing, conference paper and report writing, poster presentations, SOP drafting, teaching, research study design, and drug testing. Proficient in employing in-silico methods for drug development, including docking studies, simulation procedures, network pharmacology, and statistical predictions. Well versed with Pharmacokinetic, Pharmacometrics and Pharmacodynamic principles. Additionally, equipped with a background in quality and regulatory affairs, adept at drafting regulatory documents and quality-related SOPs. Proficient in utilizing a wide array of laboratory equipment for analysis, research, and development purposes. Demonstrating hands-on expertise in pharmacokinetics, pharmacometrics, pharmacodynamics, in-vitro and in-silico experimentation, as well as in-vivo animal studies. Possessing a solid understanding of clinical trials. Quality control professional experienced in developing organization's quality strategy, procedures and processes. Monitor quality performance from supply chain and throughout product development life cycle. Develop and sustain Quality Management System in accordance with ISO 9001 and other applicable standards and business requirements. Manage quality audit program to identify and resolve non-conformities and embed culture of continuous improvement.

Overview

22
22
years of professional experience
1
1
Certification
1
1
Language

Work History

PHD Research Scholar

Dr. Vishwanath Karad MIT-World Peace University
12.2020 - Current
  • Research topic - Targeted Breast Cancer Therapy: Metallic Nanoparticle-Entrapped Polymeric Hydrogel Delivery of Withaferin-A

Pharmacist

Sri Vigneswara Drug store
11.2007 - 02.2015
  • Proficient in reviewing electronic prescriptions, managing prescription orders, conducting narcotic reconciliations, and providing patient counseling.
  • Managed high volume of prescriptions daily while maintaining excellent customer service and attention to detail.
  • Developed strong relationships with healthcare providers to optimize patient care and medication adherence.
  • Maintained appropriate drug records and completed reports as necessary.
  • Reviewed prescription to confirm appropriate selection of drug, dose and check for interactions with other medications.
  • Interpreted prescription orders, dispensed medications, and counseled patients on drugs.
  • Assisted in the development of policies and procedures related to pharmacy operations, promoting compliance with legal regulations and best practices.
  • Conducted regular audits of the pharmacy''s controlled substances inventory, ensuring accurate record-keeping and preventing diversion or theft.
  • Evaluated drug therapy to drive appropriate medicine use.
  • Assessed patient knowledge of chosen therapy to tailor counseling to meet needs of individual patients.
  • Reported adverse drug events to comply with regulatory policies and procedures.
  • Conducted thorough drug utilization reviews to identify potential drug interactions or contraindications, ensuring patient safety.
  • Implemented medication therapy management programs, resulting in improved patient adherence to prescribed medications.
  • Prepared medications in blister packs to provide safe and convenient way to take prescribed medication.
  • Managed drug and supply inventories.
  • Advised patients on medication side effects and contraindications and explained proper administration.
  • Performed technical processes required to dispense medications to patients.
  • Effectively prioritized tasks and organized workflow to increase efficiency.
  • Hand counted controlled medications, measured liquids and reconstituted antibiotics.
  • Achieved and maintained top customer satisfaction and retention by cultivating productive relationships with patients.
  • Completed accurate cycle counts, inventory management and will-calls for customers.

Lecturer

Vasavi Jnana Peetha College of Pharmacy
11.2003 - 06.2004
  • Engaged in teaching pharmacy practice and industrial pharmacy, including lecturing, grading, and organizing course materials.
    • Conduct extensive research on recent studies and discoveries in pharmaceuticals to incorporate new information into teaching materials.
    • Conduct evaluations and tests to assess student proficiency levels and evaluate the effectiveness of the curriculum.
    • Strive to provide a dynamic and enriching learning experience for students.
    • Stay updated with the latest advancements in the pharmaceutical industry.

Research Analyst

Drug testing laboratory, Centre for Advanced Drug research and testing (CADRAT), J.S.S. College of Pharmacy
10.2002 - 09.2003
  • • Meticulously analyzed diverse drugs and formulations following official methods.
    • Developed and validated analytical procedures for estimating drugs within formulations.
    • Specialized in creating methods for estimating drugs within formulations.
    • Developed stability-indicating assays crucial for assessing the integrity and shelf life of drugs.
    • Utilized sophisticated analytical and chromatographic methods including HPLC, HPTLC, GC, UV, and IR.
    • Contributed to ensuring the quality, safety, and efficacy of pharmaceutical products through advanced analytical techniques.
    • Quality audit
    • Quality risk management (CAPA)
    • QBD, TQM
    • ISO standards
    • Lean principles and Six sigma principles
    • Stability and dissolution studies as per ICH guidelines
    • Regulatory guidelines of all countries

Education

Ph.D. - Pharmaceutics

School of Health Sciences And Technology, MIT WPU
Pune, Maharashtra, India
12.2024

Master of Science - Quality Assurance Techniques

Poona College of Pharmacy, BVDU
Pune, Maharashtra, India
10.2019

Bachelor of Science - Pharmaceutical Sciences

KMCH College of Pharmacy, Dr. MGR Medical Uni
Coimbatore, Tamil Nadu, India
10.2000

Higher Secondary - Mathematics And Science

Bethlehem Girls Higher Secondary School
Ootacamund, The Nilgiris, India
03.1996

High School Diploma -

Bethlehem Girls Higher Secondary School
Ootacamund, The Nilgiris, India
04.1994

Skills

SKILLS
Formulation and Development:

 Polymeric Nano Particles
 Liposomes
 Metallic Nano Particles
 Polymeric Hydrogel
 Hybrid Systems
Extraction procedures
 Soxhlet apparatus,
 Supercritical CO2 extraction
 Other types of extractions
Dissolution and disintegration studies Stability studies as per ICH guidelines
Quality control procedures
 Quality risk management tools
 Validation
 Lean manufacturing
 Six sigma
 CGMP implementation
 Good Laboratory Practices (GLP)
 Project management
 Team work
 Quality Assurance
 Quality Control
 Quality auditing
 ISO standards
 Quality assurance standards
 Quality Assurance Controls
 Monitoring therapeutic effectiveness
 Regulatory Compliance
 Documentation abilities
 Pharmaceutical Calculations
 Quality review processes
 Quality by Design (QbD) concepts
 Total Quality Management (TQM)
 Corrective and Preventive action (CAPA)
 Validation procedures
 SOP drafting
 Statistical analysis
 FDA Drug Safety Guidelines
 Pharmacy Software Mastery
 Regulatory Standards
 Audit Support
 Process Improvements
 Loss prevention controls
 Contract manufacturing documents
 Analytical chemistry
 Quality risk management tools
 Root cause analysis
 Quality management systems
 Lean manufacturing tools
 Drafting SOPs and quality documents
 Drug regulatory guidelines (ICH and global guidelines specific to various countries)
Instruments handling
 TEM, SEM, UV, IR, HPLC, HPTLC, DLS, and GC
In silico methods
 Docking (Auto dock-Vina, Schrodinger)
 Simulation (Desmond)
 Network pharmacology (Cytoscape, David, ShinyGo)
 Network enrichment
 Network clustering and topology
In vitro studies
 Cell line studies
 ELISA
 MTT assay
 Western blot
 Bioassays (other)
In vivo studies
 Animal handling and Experimentation
 Pharmacokinetic principles and procedures
 Pharmacometrics principles and procedures
 Pharmacodynamic principles and procedures

Medical softwares
 GastroPlus Matlab,
 Phoneix modeling and simulation, Schrodinger,
 Auto-dock vina
 Desmond
 Maestro
 PyMOL
 State Ease
 Grap Pad prism
 Endnote
 Mendeley
 Zotero
 Currently learning R software and python
Documentation
 Scientific writing
 Research proposal writing
 Research protocol preparation Development of SOPs for instruments and validation procedures
Method development and analysis
 HPLC and HPTLC Method development
 Dissolution studies as per regulatory guidelines
 Stability studies as per ICH guidelines
 UV analysis
 IR analysis
 SEM analysis
 TEM analysis
 HPLC analysis
 HPTLC analysis
 DLS analysis
 Gas Chromatography
 In vitro methods (ELISA, Western blot, MTT)
 In vivo methods
 Animal handling and Experimentation
 In silico methods
Others
 Skilled in conducting systematic reviews and meta-analysis procedures
 Proficient in reviewing electronic prescriptions and dispensing
AI tools
 Chat-GPT
 Bard
 Quillbot

Computer Skills
 Python
 R software
 Empower 1-3
 EZ chrome Elite
 Completed DNCC (1-year course)
 Languages Covered - MS –Office (Word, Excel, Power point, Outlook), MS-Access, Windows 2K, C, C, SQL server 70, Java, Soft Eng, Visual basic, Linux
 End note
 Mendeley

Accomplishments

Research Publications

1. Integrating Network Pharmacology and In Silico Analysis Deciphers Withaferin-A’s Anti-Breast Cancer Potential Via Hedgehog Pathway and Target Network Interplay.

Journal name: Briefings in Bioinformatics

Impact factor: 13.99

Paper type: Research paper

Status: Published

Publisher: Oxford University press

Citation: Mythili Srinivasan, Apeksha Gangurde, Ashwini Y Chandane, Amol Tagalpallewar, Anil Pawar, Akshay M Baheti, Integrating network pharmacology and in silico analysis deciphers Withaferin-A’s anti-breast cancer potential via hedgehog pathway and target network interplay, Briefings in Bioinformatics, Volume 25, Issue 2, March 2024, bbae032, https://doi.org/10.1093/bib/bbae032

2. Herbal Pioneers: Advancing Pulmonary Health via Novel Drug Delivery Methods

Journal name: European Journal of Integrative Medicine

Cite score: 3.9

Impact factor: 2.5

Paper type: Review article

Status: Under review

3. Kerala’s Anticancer Flora: A Comprehensive Review

Journal name: Journal of Applied Pharmaceutical Science

Cite score: 2.4

Paper type: Systematic Review

Status: Under publication

Date of Communication: December, 2023, Volume16, Issue: 3

4. "Exploring Potential Compounds for the Treatment of Alzheimer's Disease: A NetworkPharmacology and Molecular Docking Approach"

Journal name: Biomolecular Structure and design

Impact factor: 4.4

Paper type: Research paper

Status: Under second review

Publisher: Elsevier

5. Development and in vitroeffectiveness of tooth gel containing herbal extracts

Journal name: Research Journal of Pharmacy and Technology

Impact factor: 1.3

Paper type: Research paper

Status: Published

Publication Details: March, 2023, Volume16, Issue: 3

Citation: Mythili Srinivasan, Deshmukh Apurva, Wani Manish, Polshettiwar Satish, Pande Varun, Deshpande Maitreyee, Pandit Ashlesha, Tagalpallewar Amol, Baheti Akshay. Development and In-vitro Effectiveness of Tooth-gel containing Herbal Extracts. Research Journal of Pharmacy and Technology 2023; 16(3):1283-8. doi: 10.52711/0974-360X.2023.00211

6. Pharmacokinetic and Pharmacodynamic interactions of Andrographolide with Meloxicam in Wistar-rats.

Journal name: Modern Chemistry and Applications.

Impact factor: 1.37

Paper type: Research paper

Status: Published

Publication Details: Dec 11, 2019, Volume 7, Issue: 1:268

Citation: Mahadik KR, Srinivasan M, Sathiyanarayanan L, Arulmozhi S (2019) Pharmacokinetic and Pharmacodynamic Interaction of Andrographolide with Meloxicam in Wistar rats. Mod Chem Appl 7:268. doi: 10.35248/2168-975X.19.7.268

7. A systematic Review on Therapeutic potential of king of bitters (Andrographis paniculata (Nees))

Journal name: International journal of Pharmacy and Pharmaceutical research.

Impact factor: 5.01

Paper type: Review paper

Status: Published

Publication details: Vol. 19 (1): 755-768

Citation: Sathiyanarayanan Lohidasan et al. Ijppr.Human, 2020; Vol. 19 (1): 755-768

8. Role of natural products in breast cancer management – An overview

Journal name: International journal of Pharmacy and Pharmaceutical research.

Impact factor: 5.01

Paper type: Review paper

Status: Published.

Publication Details: Nov 2019, Volume 16, issue: 4

Citation: Sathiyanarayanan Lohidasan et al. Ijppr. Human, 2019; Vol. 16 (4): 9-39.

9. Network pharmacology and in-vivo studies for analgesic and antipyretic activities of Haplanthodes tentaculata (L) leaves

Journal name: European Journal of Integrative Medicine

Cite score: 3.9

Impact factor: 2.5

Paper type: Research article

Status: Under review COCURRICULAR ACHIEVEMENTS:

v Participated in International MRS Spring Research Summit 2024 held at Seattle, Washington, United States from 22nd to 26th April, 2024.

v Poster presentation on “Advanced Breast Cancer Therapy: Thermosensitive Hybrid Hydrogel (PLGA-PEG-PLGA) with Metallic Nanoparticles Enhancing Withaferin-A Release" at MRS Spring Research Summit 2024 held at Seattle, Washington, United States held on 23rdApril, 2024.

v Participated in the International Symposium on “Emerging trends in drug discovery” - November 2018, held at Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University).

v Participated in poster presentation competition “Ethnomedicine: Prospects and challenges in Global healthcare scenario”- February 2018, organized by Indira College of Pharmacy, Pune, India.

v Participated in a two-day National Level Conference on “Ethnomedicine: Prospects and challenges in Global healthcare scenario” - February 2018, organized by Indira College of Pharmacy, Pune, India.

Certification

  • Prescription Drug Regulation, Cost and Access -P.G. Diploma course, Harvard University - June 2020
  • Six-sigma – Currently pursuing
  • R software – Currently pursuing
  • Pharmacist Registration License Certificate issued by Pharmacy Council of India.

Alternate Mobile

+91-9665033311

Research Publications

Research Publications

1. Integrating Network Pharmacology and In Silico Analysis Deciphers Withaferin-A's Anti-Breast Cancer Potential Via Hedgehog Pathway and Target Network Interplay.

Journal name: Briefings in Bioinformatics

Impact factor: 13.99

Paper type: Research paper

Status: Published

Publisher: Oxford University press

Citation: Mythili Srinivasan, Apeksha Gangurde, Ashwini Y Chandane, Amol Tagalpallewar, Anil Pawar, Akshay M Baheti, Integrating network pharmacology and in silico analysis deciphers Withaferin-A's anti-breast cancer potential via hedgehog pathway and target network interplay, Briefings in Bioinformatics, Volume 25, Issue 2, March 2024, bbae032, https://doi.org/10.1093/bib/bbae032

2. Herbal Pioneers: Advancing Pulmonary Health via Novel Drug Delivery Methods

Journal name: European Journal of Integrative Medicine

Cite score: 3.9

Impact factor: 2.5

Paper type: Review article

Status: Under review

3. Kerala's Anticancer Flora: A Comprehensive Review

Journal name: Journal of Applied Pharmaceutical Science

Cite score: 2.4

Paper type: Systematic Review

Status: Under publication

Date of Communication: December, 2023, Volume16, Issue: 3

4. "Exploring Potential Compounds for the Treatment of Alzheimer's Disease: A Network Pharmacology and Molecular Docking Approach"

Journal name: Biomolecular Structure and design

Impact factor: 4.4

Paper type: Research paper

Status: Under second review

Publisher: Elsevier

5. Development and in vitro effectiveness of tooth gel containing herbal extracts

Journal name: Research Journal of Pharmacy and Technology

Impact factor: 1.3

Paper type: Research paper

Status: Published

Publication Details: March, 2023, Volume16, Issue: 3

Citation: Mythili Srinivasan, Deshmukh Apurva, Wani Manish, Polshettiwar Satish, Pande Varun, Deshpande Maitreyee, Pandit Ashlesha, Tagalpallewar Amol, Baheti Akshay. Development and In-vitro Effectiveness of Tooth-gel containing Herbal Extracts. Research Journal of Pharmacy and Technology 2023; 16(3):1283-8. doi: 10.52711/0974-360X.2023.00211

6. Pharmacokinetic and Pharmacodynamic interactions of Andrographolide with Meloxicam in Wistar-rats.

Journal name: Modern Chemistry and Applications.

Impact factor: 1.37

Paper type: Research paper

Status: Published

Publication Details: Dec 11, 2019, Volume 7, Issue: 1:268

Citation: Mahadik KR, Srinivasan M, Sathiyanarayanan L, Arulmozhi S (2019) Pharmacokinetic and Pharmacodynamic Interaction of Andrographolide with Meloxicam in Wistar rats. Mod Chem Appl 7:268. doi: 10.35248/2168-975X.19.7.268

7. A systematic Review on Therapeutic potential of king of bitters (Andrographis paniculata (Nees))

Journal name: International journal of Pharmacy and Pharmaceutical research.

Impact factor: 5.01

Paper type: Review paper

Status: Published

Publication details: Vol. 19 (1): 755-768

Citation: Sathiyanarayanan Lohidasan et al. Ijppr.Human, 2020; Vol. 19 (1): 755-768

8. Role of natural products in breast cancer management – An overview

Journal name: International journal of Pharmacy and Pharmaceutical research.

Impact factor: 5.01

Paper type: Review paper

Status: Published.

Publication Details: Nov 2019, Volume 16, issue: 4

Citation: Sathiyanarayanan Lohidasan et al. Ijppr. Human, 2019; Vol. 16 (4): 9-39.

9. Network pharmacology and in-vivo studies for analgesic and antipyretic activities of Haplanthodes tentaculata (L) leaves

Journal name: European Journal of Integrative Medicine

Cite score: 3.9

Impact factor: 2.5

Paper type: Research article

Status: Under second review

10. Nilgiri medicinal Plants

Book Chapter

Publisher: Scrinevier

Status: Under Publication

Co Curricular Achievements

  • Participated in International MRS Spring Research Summit 2024 held at Seattle, Washington, United States from 22nd to 26th April, 2024.
  • Poster presentation on “Advanced Breast Cancer Therapy: Thermosensitive Hybrid Hydrogel (PLGA-PEG-PLGA) with Metallic Nanoparticles Enhancing Withaferin-A Release" at MRS Spring Research Summit 2024 held at Seattle, Washington, United States held on 23rd April, 2024.
  • Participated in the International Symposium on “Emerging trends in drug discovery” - November 2018, held at Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University).
  • Participated in poster presentation competition “Ethnomedicine: Prospects and challenges in Global healthcare scenario”- February 2018, organized by Indira College of Pharmacy, Pune, India.
  • Participated in a two-day National Level Conference on “Ethnomedicine: Prospects and challenges in Global healthcare scenario” - February 2018, organized by Indira College of Pharmacy, Pune, India.

Education Summary

  • PHD, School of Health Sciences and technology, Dr Vishwanath Karad’s MIT-WPU, 2020 Dec-2024 June (Final Year), Pre PHD exams -98%
  • M. Pharm, Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University), September - 2019, 9.05, A+ (Distinction)
  • B. Pharm, KMCH College of Pharmacy, Dr. M.G.R Medical University, October - 2000, 65% (First Class)
  • H.S.C., Bethlehem Girls Higher Secondary School, Tamil Nadu State Board, March - 1996, 73.5%
  • S.S.C., Bethlehem Girls Higher Secondary School, Tamil Nadu State Board, April - 1994, 88% (Distinction)

Disclaimer

I hereby declare that the above information is true to the best of my knowledge and belief.

Affiliations

  • Research Scholar (Final Year PHD)

Additional Information

STRENGTHS:

Good oral communication and presentation skills. Practical and disciplined, Logical and methodical.

Additional Certifications

1) Prescription Drug Regulation, Cost and Access -P.G. Diploma course, Harvard University - June 2020

2) Six-sigma – Currently pursuing

3) R software – Currently pursuing

Languages

English
Full Professional

Quote

The price of anything is the amount of life you exchange for it.
Henry David Thoreau

Work Availability

monday
tuesday
wednesday
thursday
friday
saturday
sunday
morning
afternoon
evening
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Software

Python R software Empower 1-3 EZ chrome Elite Completed DNCC (1-year course) Languages Covered - MS –Office (Word, Excel, Power point, Access, Outlook), MS-Access, Windows 2K, C, C, SQL server 70, Java, Soft Eng, Visual basic, Linux End note Mendeley

Timeline

PHD Research Scholar

Dr. Vishwanath Karad MIT-World Peace University
12.2020 - Current

Pharmacist

Sri Vigneswara Drug store
11.2007 - 02.2015

Lecturer

Vasavi Jnana Peetha College of Pharmacy
11.2003 - 06.2004

Research Analyst

Drug testing laboratory, Centre for Advanced Drug research and testing (CADRAT), J.S.S. College of Pharmacy
10.2002 - 09.2003

Ph.D. - Pharmaceutics

School of Health Sciences And Technology, MIT WPU

Master of Science - Quality Assurance Techniques

Poona College of Pharmacy, BVDU

Bachelor of Science - Pharmaceutical Sciences

KMCH College of Pharmacy, Dr. MGR Medical Uni

Higher Secondary - Mathematics And Science

Bethlehem Girls Higher Secondary School

High School Diploma -

Bethlehem Girls Higher Secondary School

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