Nazanin Mokhtarpour
Redmond,WA
Summary
Analytical scientist with experience in method development, LC-MS/MS, HPLC, and regulated bioanalytical workflows supporting drug development. Background includes method qualification, troubleshooting, stability testing, and supporting technology transfer activities. Strong documentation skills with experience in GMP-aligned environments, QC laboratory operations, and cross-functional collaboration with R&D, QA, and external partners. Interested in nanoparticle formulation, analytical control strategies, and bridging R&D methods into GMP readiness.
Overview
8
8
years of professional experience
Work History
Bioanalytical Scientist II
Medpace Bioanalytical Laboratories
Cincinnati, OH
12.2024 - 06.2026
- Developed, optimized, and executed analytical methods (LC-MS/MS, HPLC) to support clinical and nonclinical studies, including identity, purity, and stability assessments.
- Performed sample preparation (protein precipitation, LLE, SPE) and executed routine and non-routine analytical testing with strong troubleshooting capability.
- Supported method qualification and transfer activities, contributing to transfer documentation, data packages, and communication with partner labs.
- Conducted PK sample analysis, calibration curve generation, QC evaluation, and data verification to ensure data integrity.
- Maintained GMP-aligned documentation, including protocols, validation reports, controlled records, and experimental summaries.
- Collaborated with QA, project managers, and scientific teams to support program timelines and analytical readiness.
- Performed instrument maintenance, calibration, and performance monitoring to ensure analytical reliability.
Bioanalytical Scientist I
Medpace Bioanalytical Laboratories
Cincinnati, OH
10.2022 - 12.2024
- Developed and validated analytical methods for small-molecule drug candidates, supporting formulation and process development activities.
- Executed stability studies, impurity profiling, and characterization experiments to support formulation screening and process optimization.
- Assisted with tech transfer preparation, including drafting method transfer protocols and supporting comparability assessments.
- Maintained high-quality experimental records and contributed to technical reports and cross-functional data reviews.
- Supported QC-related activities including batch documentation review, data verification, and deviation investigation support.
Research Assistant
University of Cincinnati
Cincinnati, OH
08.2019 - 12.2022
- Conducted organic synthesis of small molecules, including multi-step reaction design, purification, and structural characterization.
- Characterized compounds using MALDI-TOF, NMR, UV-Vis, ITC, and chromatographic techniques.
- Performed protein–ligand interaction studies and supported structure–activity relationship (SAR) analysis.
- Designed and optimized synthetic routes and analytical workflows to support medicinal chemistry programs.
- Prepared technical reports, manuscripts, and scientific presentations.
- Maintained detailed laboratory records and contributed to method optimization.
Graduate Research Assistant
Mississippi State University
Starkville, MS
01.2018 - 12.2018
- Designed and executed organic synthesis experiments, including reaction setup, monitoring, purification, and characterization.
- Characterized compounds using GC-MS, IR spectroscopy, and other analytical tools.
- Developed laboratory SOPs and supported experimental design, data analysis, and documentation.
Education
Ph.D. - Medicinal Chemistry
University of Cincinnati
Cincinnati, OH01-2022
M.Sc. - Organic Chemistry
Ferdowsi University of Mashhad
Mashhad, Iran01-2015
B.Sc. - Chemistry
University of Mazandaran
Iran01-2013
Skills
- Analytical Method Development & Qualification
- LC-MS/MS, HPLC, GC-MS, ICP-MS
- Stability Studies & Characterization
- Method Transfer & Tech Transfer Support
- GMP/GDP Documentation Practices
- QC Laboratory Operations
- Cross-Functional Collaboration (R&D, QA/QC, CDMOs)
- Troubleshooting & Data Interpretation
- Sample Preparation (PPT, LLE, SPE)
- Experimental Design & Process Support
- Organic Chemistry: Multi-step synthesis, reaction optimization, purification, structural elucidation
- Analytical Techniques: HPLC/UPLC, LC-MS/MS, GC-MS, NMR, MALDI-TOF, ITC, UV-Vis, FTIR
- Software: Analyst, Sciex OS, Empower, MS Office, statistical tools
- Documentation: SOPs, validation reports, regulatory documentation
- Regulatory: GLP/GMP, method lifecycle documentation, data integrity (ALCOA)
Languages
English
Native or Bilingual
ADDITIONAL STRENGTHS
- Strong scientific judgment and troubleshooting ability
- Excellent communication skills for leading cross-functional discussions
- Ability to manage multiple priorities in fast-paced environments
- High attention to detail and commitment to quality
Timeline
Bioanalytical Scientist II
Medpace Bioanalytical Laboratories
12.2024 - 06.2026
Bioanalytical Scientist I
Medpace Bioanalytical Laboratories
10.2022 - 12.2024
Research Assistant
University of Cincinnati
08.2019 - 12.2022
Graduate Research Assistant
Mississippi State University
01.2018 - 12.2018
M.Sc. - Organic Chemistry
Ferdowsi University of Mashhad
B.Sc. - Chemistry
University of Mazandaran
Ph.D. - Medicinal Chemistry
University of Cincinnati