Olakunle Jaiyesimi
Cambridge,USA
One second, the one we are in, is the most important of all. Use it wisely!
Olakunle
Summary
Postdoctoral Fellow with 4+ years in fellowship at Harvard University, Cambridge and Georgia Institute of Technology, Atlanta. Organized with research focused on bioinformatics approaches including LC-MS-based untargeted metabolomics and transcriptomics, characterization of isolated compounds, and structure-activity relationship studies amongst others. Presentations educating students, peers and superiors on research analysis. Published research findings through peer-reviewed articles and analyzed results tailoring to potential future applications. Gaining deeper insights into the workings of human biology constitutes a core motivation for me. Most recently, I have experience applying artificial intelligence to varied workflows.
Overview
11
11
years of professional experience
Work History
Postdoctoral Fellow
Harvard University
06.2022 - Current
- I utilize untargeted metabolomics followed by functional genetic approaches to interrogate the molecular mechanisms, particularly genetic mechanisms, underlying the reproductive and developmental phenotypes; and evolutionary interactions of fruit flies (Drosophilids) with their environment.
- I use machine learning to select important biomarkers for adequate interpretation.
- I integrate metabolomics with genomics and transcriptomics strategies to decipher molecular phenotypes.
Postdoctoral Fellow
Georgia Institute of Technology
09.2020 - 05.2022
- I researched host-microbe, microbe-antibiotic, and microbe-microbe interactions in the context of cystic fibrosis lung chemical environment using untargeted metabolomics approaches.
- I researched marine coral-microbe symbiosis, and mammalian host epithelium-pathogen chemical interactions using untargeted metabolomics approaches.
Research Scientist
Georgia Institute of Technology
09.2019 - 09.2020
- I researched host-microbe, microbe-antibiotic, and microbe-microbe interactions in the context of cystic fibrosis lung chemical environment
- I researched marine coral-microbe symbiosis, and mammalian host epithelium-pathogen chemical interactions using untargeted metabolomics approaches.
Teaching Assistant
University of Sao Paulo
01.2018 - 06.2018
- Assisted in teaching activities at the Faculty of Pharmaceutical Sciences of Ribeirão Preto.
Lecturer II
Obafemi Awolowo University
09.2015 - 03.2016
- I delivered lectures at the Department of Pharmacognosy, Faculty of Pharmacy.
Junior Trainee Fellow
Obafemi Awolowo University
03.2013 - 08.2015
- I engaged in training and research activities at the Department of Pharmacognosy, Faculty of Pharmacy.
- I demonstrated at laboratory sessions for students.
- I worked closely with the Head of Department to identify areas of improvement, implementing changes as needed to ensure quality learning.
Education
Ph.D. - Natural and Synthetic Products
09.2019
Advisor: Prof. Leonardo Gobbo-Neto
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Scholarship Recipient, 2016.
- Programa de Excelência Acadêmic da CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES-PROEX) Scholarship Recipient, 2016.
Master of Science - Pharmacognosy
09.2015
BPharm. - Pharmacy
02.2008
Skills
- Research Procedures
- Specific Research Projects
- Project Management
- Proficient in UPLC-MS/MS Technology
- Bioinformatics Analysis
- Scientific Communication
- Proficient in PCR Technology
- Proficient in LCMS-based untargeted metabolomics
- Proficient in Biomarker Discovery
- Biomarker Detection
- Assay Development
- ChatBot Development and Integration of Artificial Intelligence in workflows
Other Services
- Member, Support and Psychological Safety Team, Community Task Force (CTF) on Equality, Diversity, Inclusion, and Belonging (EDIB), Department of Molecular and Cellular Biology (MCB), Harvard University, 2023
- Representative, Community Task Force (CTF) on Equality, Diversity, Inclusion, and Belonging (EDIB), Harvard University Department of Molecular and Cellular Biology (MCB) 2023 Retreat Planning Committee, 2023
- Member, Harvard EDIB CTF, 2022
Grants
Motsepe Presidential Research Accelerator Fund for Africa, Motsepe Foundation, Discovering the Molecular Mechanisms Underlying Toxicity of Environmental Pollutants in Nigeria, 2023
Honors And Awards
- Programa de Excelência Acadêmic da CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES-PROEX), 2016
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), 2016
Publications
- Metabolomics analysis of bacterial pathogen Burkholderia thailandensis and mammalian host cells in co-culture, ACS Infectious Diseases, 8, 8, 1646-1662, 2022, N. Aiosa, A. Sinha, O.A. Jaiyesimi, R.R. da Silva, S.S. Branda, N. Garg
- Metabolomic profiling of Burkholderia cenocepacia in synthetic cystic fibrosis sputum medium reveals nutrient environment-specific production of virulence factors, Scientific reports, 11, 1, 1-17, 2021, O.A. Jaiyesimi, A.C. McAvoy, D.N. Fogg, N. Garg
- Metabolomics of healthy and stony coral tissue loss disease affected Montastraea cavernosa corals, Frontiers in Marine Science, 1421, 2021, J.M. Deutsch, O.A. Jaiyesimi, K.A. Pitts, J. Houk, B. Ushijima, B.K. Walker, V.J. Paul, N. Garg
- Differences in cystic fibrosis-associated Burkholderia spp. bacteria metabolomes after exposure to the antibiotic trimethoprim, ACS Infectious Diseases, 6, 5, 1154-1168, 2020, A.C. McAvoy, O. Jaiyesimi, P.H. Threatt, T. Seladi, J.B. Goldberg, R.R. da Silva, N. Garg
- LC-UV-HRMS dereplication of secondary metabolites from Brazilian Vernonieae (Asteraceae) species supported through in-house database, Biochemical Systematics and Ecology, 78, 5-16, 2018, M.E. Gallon, O.A. Jaiyesimi, L. Gobbo-Neto
- Effect of the juice of the stem and root and of Musa paradisiaca L. (Musaceae) on blood glucose level of male wistar rats, Inventi Impact: Ethnopharmacology, 2011, O.R. Omobuwajo, G.O. Alade, O.O. Makanjuola, O.A. Jaiyesimi
Accomplishments
- Collaborated with a data scientist to develop a pipeline for LC-MS blank subtraction at Georgia Institute of Technology.
Conferences, Research Seminars and Workshops
- Coven Works ChatBot Development Workshop using Google dialogueflow workflow, 2023
- Bioscience in a changing world: Setting the pace for the next generation, by Science Café, 2023
- 5th Annual Metabolomics Association of North America (MANA) Conference, University of Missouri, Columbia, 2023
- A Drosophila Outreach to Undergraduate Students in Nigeria, Drosophila Research and Training Centre, Basorun, Ibadan, Nigeria, 2023
- Invited Speaker on Metabolomics, Dr. Martin Job’s Lab, Rowan University, New Jersey, USA, 2023
- Center for Microbial Dynamics and Infection Seminar Series, Georgia Institute of Technology, Atlanta, USA, 2021
- 19th Oxford ICSB (International Conference on the Science of Botanicals), Oxford Conference Center, Univerisity of Mississippi, Oxford, Mississippi, USA, 2019
- A workshop: Development and Evaluation of Bioactive Compounds, Durham University, FCFRP/USP, Faculty of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Ribeirão Preto, Sao Paulo, Brazil, 2019
- VIII Workshop of the Graduate Program in Pharmaceutical Sciences FCFRP / USP, Faculty of Pharmaceutical Sciences of Ribeirao Preto, Sao Paulo, Brazil, 2018
- 41st Annual Meeting of the Brasilian Society of Chemistry, SBQ, Foz do Iguaçu, Brasil, 2018
- VII Workshop of the Graduate Program in Pharmaceutical Sciences FCFRP / USP, Faculty of Pharmaceutical Sciences of Ribeirao Preto, Sao Paulo, Brazil, 2017
- 11th International Congress of Pharmaceutical Sciences, CIFARP, Ribeirao Preto, Brasil, 2017
- 6th Brazilian Conference on Natural Products, Federal University of Espirito Santo, Vitoria, Espirito Santo, Brasil, 2017
- Seminar, NPPNS, Natural and Synthetic Products Research group, FCFRP, Brasil, 2017
- II CNPEM Workshop on Metabolomics, Rua Giuseppe Máximo Scolfaro, 10000, Polo II de Alta Tecnologia, Campinas, Sao Paulo, Brazil, 2016
- VI Workshop of the Graduate Program in Pharmaceutical Sciences FCFRP / USP, Faculty of Pharmaceutical Sciences of Ribeirao Preto, Sao Paulo, Brazil, 2016
- World Diabetes Day Workshop, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria, 2015
Research Interests
• Whole organism, tissue-based, and single-cell transcriptomics.
• Biomarker Discovery.
• Drug discovery and drug development.
• Personalized and precision medicine.
• Reproductive, developmental and evolutionary adaptive mechanisms.
• Exposomics.
• Molecular mechanisms of health maintenance and disease progression.
• Prediabetes and diabetes experimentations and other in vitro and in vivo assays.
• Bioactive molecular networking.
• Marine biology.
• Systems biology.
• Natural products and metabolite structural elucidations.
• Functional and network analyses.
• PCR techniques.
• ChatBot Development and integration of Artificial Intelligence
Languages
English
Native or Bilingual
Portuguese
Professional Working
Work Availability
monday
tuesday
wednesday
thursday
friday
saturday
sunday
morning
afternoon
evening
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Work Preference
Work Type
Full TimeContract WorkWork Location
RemoteOn-SiteHybridImportant To Me
401k matchPaid time offCareer advancementHealthcare benefitsPaid sick leaveWork-life balanceCompany CultureWork from home optionFlexible work hoursPersonal development programsStock Options / Equity / Profit SharingTeam Building / Company RetreatsSoftware
R
Python
Sirius
Thermo Fischer's Compound Discoverer
MzMine 3
GNPS
XCMS Online
MGWAS-Explorer 20
PathBank
Fella
MetaboAnalyst
SIMCA
Timeline
Postdoctoral Fellow - Harvard University
06.2022 - Current
Postdoctoral Fellow - Georgia Institute of Technology
09.2020 - 05.2022
Research Scientist - Georgia Institute of Technology
09.2019 - 09.2020
Teaching Assistant - University of Sao Paulo
01.2018 - 06.2018
Lecturer II - Obafemi Awolowo University
09.2015 - 03.2016
Junior Trainee Fellow - Obafemi Awolowo University
03.2013 - 08.2015
University of Sao Paulo - Ph.D., Natural and Synthetic Products
Obafemi Awolowo University - Master of Science, Pharmacognosy
Obafemi Awolowo University - BPharm., Pharmacy
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