Osama Ahmed Khan

Visionary Anatomical Pathologist with expertise in precision medicine, digital pathology, and molecular diagnostics. Over a decade of experience in leading pathology operations with involvement in biomarker research, and integrating artificial intelligence into diagnostic workflows. Passionate about advancing pathology-driven innovations in oncology and personalized medicine. Demonstrated ability to solve complex, high-impact problems while working effectively with diverse teams. Committed to continuous improvement and contributing to the achievement of team and organizational goals.

• Association of Molecular Pathology
• International Society of Urological Pathology (ISUP)
• Genitourinary Pathology Society (GUPS)
• United States and Canadian Academy of Pathology (USCAP) Ambassador
• College of American Pathologists (CAP)
• Delegate Member American Society for Clinical Pathologists (ASCP)
• Canadian Medical Association (CMA) Ambassador
• Ontario Medical Association (OMA) Section of Interns and Residents Members

• From Glass Slides to AI: How Digital Pathology and MRD Testing Are Transforming Cancer Care, Oncology Data Advisor Podcast, 02/2025
• Cracking the Carms. Practical Interview Preparation Seminar., 01/06/25, Internationally Trained Physicians of Ontario (ITPO)
• Invited Speaker at Medical School Information Session., 12/07/24, GUS Medical and Veterinary Schools, New York City, New York
• Care GAP? Frozen Section Diagnosis in the Digital Era., 12/04/24 - 12/05/24, Advanced Digital Solutions at Precipoint
• Natera Clinical Case Review for Medical Science Liaisons, Natera, 03/01/24
• Successful Outcomes: From Saba University to a Stanford Fellowship, 10/15/22, UC Davis Pre-Health Conference, Davis, California
• Competency By Design (CDB) implementation in the Department of Anatomical Pathology Program at the University of Ottawa, 09/23/19, Competency By Design Program Evaluation Summit, Ottawa, Ontario
• Competency By Design (CDB) implementation in the Department of Anatomical Pathology Program at the University of Ottawa, 03/01/20, Association of Pathology Chair's (APC) spring meeting as part of the 2020 USCAP annual meeting
• Ki-67 expression and FDG uptake in Colorectal Adenomas and Adenocarcinoma, 03/01/20, Grand Rounds Department of Nuclear Medicine – The Ottawa Hospital

• Molecular characterization of Urachal Neoplasms, 07/01/21 - Present, Stanford University
• Renal cell carcinoma metastatic to pancreas is associated with a distinct molecular profile and immune cell population., 10/01/21 - Present
• Molecular characterization of Plasmacytoid Urothelial Carcinoma, 07/01/19 - 2021, Pathology and Laboratory Medicine (PALM) Funding Research Grant ($10000)
• Competency By Design (CBD) implementation in the Department of Anatomical Pathology Program at the University of Ottawa, 07/01/19 - 2021
• Ki-67 expression and FDG uptake in Colorectal Adenomas and Adenocarcinoma., 07/01/18 - 07/01/19
• Observations of the morphological Evolution of Neuronal Intranuclear Rods in the Human Substansia Nigra Across the Age Spectrum, 07/01/18 - 2021
• Pathology Cancer Clinic – An Innovative Model to Enhance the Quality of Patient Care For Women with Gynecologic Cancer at The Ottawa Hospital, 07/01/18 - 06/01/21
• Estimating the Burden of Osteoporosis –Related Fractures in Terms of Health-Related Quality of Life, Utility and Resource Use (BOOST) observational study, 01/01/13 - 04/01/16
• A Multicenter, International, Randomized, Double-blind, placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of AM 785 Treatment in Postmenopausal Women With Osteoporosis., 01/01/13 - 04/01/16
• Atypical femoral fractures and potential association with extended bisphosphonate use, 01/01/13 - 04/01/15
• Prospective Observational Study to Evaluate the Persistence with Prolia (Denosumab) in Postmenopausal Women with Osteoporosis in Routine Clinical Practice, 01/01/13 - 04/01/14
• Medication Use Patterns, Treatment Satisfactions, and Inadequate Control of Osteoporosis Study (MUSIC-OS) Observational Study Program at the University of Ottawa, 01/01/13 - 2014

• Stanford University Clinical Fellow Teaching Award, 06/01/22
• USCAP Stowell Orbison Poster Finalist, 03/01/22
• College of American Pathologists (CAP) Engaged Leadership Academy, 03/01/22
• American Society for Clinical Pathologists (ASCP) 40 Under Forty Honoree, 03/01/22
• USCAP/ASCP “Excelerate” Leadership Scholarship Award, 12/01/19
• Association of Pathology Chairs (APC) Society of ’67 Scholars Open Access Award, 07/01/19
• Association of Pathology Chairs (APC) Society of ’67 Scholars Travel Award Recipient, 07/01/19
• CMA Ambassador Scholarship to attend Canadian Conference on Physician Leadership, 07/01/19
• ASCP Best Internationalist Abstract Finalist, 09/01/19
• USCAP/ASCP Leadership Scholarship Recipient and “Just Say Know”, 03/01/19
• College of American Pathologists (CAP) Foundation Leadership Award, 12/01/18
• ASCP Travel Award Scholarship, 08/01/18

• The genomic landscape and outcomes of renal cell carcinoma with metastases to the pancreas., Michael Glover, Arya Ashok, Osama Khan, Chia-Sui Kao, Ryan Chiang, Elizabeth Mauer, Alexander S. Barrett, Christian R. Hoerner, Sumit Shah, Sandy Srinivas, Alice C. Fan, and Ali Raza Khaki., Stanford University, Submitted
• Molecular Characterization of Urachal Neoplasms., Khan, O, Kunder, C, Kao, CS, Sangoi, A., In Press
• Challenging testicular germ cell tumor diagnoses in post-chemotherapy resection specimens., Osama Khan, Thomas M. Ulbright, Chia-Sui Kao., Diagnostic Histopathology, 28, 6, 2022, 280-284
• Giant Cell Tumor of Tendon Sheath., O. Khan, B. Purgina., My Pathology Report, 05/03/20, http://www.mypathologyreport.ca/giant-cell-tumour-of-tendon-sheath/
• Pathology Cancer Clinic – An Innovative Model to Enhance the Quality of Patient Care For Women with Gynecologic Cancer at The Ottawa Hospital., O. Khan, A. Lafreniere, A. Busca, G. Gray, S. Petkiewicz, K. Williams, T. Le, J. Weberpals, L. Hopkins, S. Islam., Academic Pathology, Submitted, 2019
• A Randomized, Double-Blind, Placebo-Controlled study to evaluate the effects of Alendronate (ALN) on bone mineral density (BMD) and bone turnover in perimenopausal women with low BMD., Aliya Khan, Sacha Dubois, Amina A Khan, Zohair Rahman, O Ahmed Khan, Hamid T Syed, Christine Derzko., J Obstet Gynaecol Can, 36, 11, 2014, 976–982
• Vitamin D and Calcium Supplements – Current Evidence for Benefit and Harm., Osama A Khan MD, David A. Hanley MD FRCPC., Canadian Journal of Diagnosis, November 2014
• Giant cell arteritis or tension-type headache? - A differential diagnostic dilemma., Khan O.A, Rana A.Q., Saeed U., Qureshi A.M., Paul D., J Neurosci Rural Pract., 2014, 409-411
• Atypical Femoral Fractures: Key Pearls from 2013 ASBMR.Task Force Report and Current Technology., Osama A Khan MD, Angela Cheung MD., Canadian Journal of Diagnosis, 2014
• Atypical Femoral Fractures: Radiographic and Histomorphemetric Features in 19 patients., Khan, A, Cheung, A, Khan, OA, Rahman, Z, Pritzker, K, Lentle, B., J Clin Densitom, 2014, 402-403
• New Mutations Causing Familial Parkinsonism., Abdul Qayyum Rana, Talal Al-Harbi, Osama Khan, Ami Patel., Ann Acad Med Singapore., 2013, 37-38
• Progressive ataxia associated with ocular apraxia type 1 (AOA1) with a Presence of a Novel Mutation on the Aprataxin Gene: A Case Report., Abdul Qayyum Rana, Osama A Khan, Raza Akthar., Ann Indian Acad Neurol, 2013, 269-271
• The use of A1C for the Diagnosis of Diabetes., Osama A. Khan MD, Manoela Braga MD., Canadian Journal of Diagnosis, January 2013 issue
• Alcohol related fatal brain injury causing multiple types of hemorrhagic lesions., Mohammed A. Rana, Osama Khan, Iftikharul Haq., JPRLS.

• Molecular Characterization of Urachal Neoplasms, 03/01/22, United States and Canadian Association of Pathologists (USCAP), Los Angeles, California
• Renal cell carcinoma metastatic to pancreas is associated with a distinct molecular profile and immune cell population., 02/01/22, Genitourinary American Society of Clinical Oncology Meeting, San Francisco, California
• Competency By Design (CBD) implementation in the Department Anatomical Pathology Program at the University of Ottawa – Platform Presentation, 03/01/20, United States and Canadian Association of Pathologists (USCAP), Los Angeles, California
• Molecular Characterization of Plasmacytoid Urothelial Carcinoma (PUC), 10/01/19, Ontario Molecular Pathology Research Network (OMPRN) annual meeting, Ottawa, Ontario
• Competency By Design (CBD) implementation in the Department of Anatomical Pathology Program at The University of Ottawa., 09/01/19, CBD Program Evaluation Summit – International Conference on Residency Education (ICRE), Ottawa, Ontario
• Ki-67 expression and FDG uptake in Colorectal Adenomas and Adenocarcinoma, 07/01/18, European Association of Nuclear Medicine (EAMN), Dusseldorf, Germany
• Observations of the morphological evolution of Neuronal Intranuclear Rods in the Human Substansia Nigra Across the Age Spectrum, 09/01/19, American Society of Clinical Pathology (ASCP), Phoenix, Arizona
• Best International Poster Finalist, 03/01/19, United States and Canadian Association of Pathologists (USCAP), National Harbor, Maryland
• Pathology Cancer Clinic – An Innovative Model to Enhance the Quality of Patient Care For Women with Gynecologic Cancer at The Ottawa Hospital, 09/01/18, Canadian Association of Pathologists Annual Meeting, Quebec City, Quebec
• American Clinical Society of Pathology (ASCP) Conference, 04/01/18, Baltimore, Maryland

• ACLS Certified
• Good Clinical Practice (GCP) certification (certified 2012 and recertified November 2014)
• Proficient in Electronic Medical Record Software (CureMD, AbelMed)
• Microsoft Office 2010, SPSS & SAS Statistical Analysis Software
• Enjoy playing Football, Ball Hockey, Tennis, Badminton, Hiking