Patrick Claude

• Accomplished Research Organic/Medicinal Chemist with broad expertise in Carbohydrate and Glycoconjugates and success in multi-step synthesis, analysis, of various classes of compounds oriented toward medical-pharmaceutical and agro-chemical applications, seeking with my broad experience to make contributions in industrial settings for new drugs development. My key areas of expertise are:
• Carbohydrates and Glycoconjugates
• Heterocyclic Compounds
• Organometallics in Organic Synthesis
• Small Molecules, Process Chemistry
• Natural Products Synthesis
• Parallel Synthesis, Large Scale Synthesis
• Peptides and Peptidomimetics Chemistry
• Asymmetric Synthesis

Dedicated educator with a strong foundation in curriculum development and student engagement. Proven ability to collaborate effectively within teams and adapt to evolving educational needs. Equipped with expertise in instructional strategies, classroom management, and fostering positive learning environments. Consistently focused on achieving tangible results and supporting student success.

• Achieved [Result] by completing [Task] with accuracy and efficiency.
• Supervised team of [Number] staff members.
• Documented and resolved [Issue] which led to [Results].
• Resolved product issue through consumer testing.

• Seven years of experience and hands-on in Carbohydrate and Glycoconjugate Chemistry
• Developed, designed and achieved the total stereo and region-selective efficient synthetic methodology of cyclic disaccharides by “Intra-molecular Glycosylation”, which goals and achievements are the creation and production of difficult glycoside linkages present in natural glycoconjugates that are unachievable by the conventional glycosylation method with important application of transforming these cyclic disaccharides products to polysaccharides for production of glycoconjugates vaccines, glycoconjugates of medicinal relevance. Other applications are SAR, Bioconjugation, Click Chemistry, Active Pharmaceutical Ingredients, (API)

• Several years of experience and achievements in synthetic methodology, multi-step synthesis of complex cyclic compounds, optimization of reaction conditions of small, medium to large scale-up synthesis of natural compounds small and complex intermediates of medicinal relevance. Applications to, Aptamers, Structure Activity Relationship, (SAR) Active, Pharmaceutical Ingredients, (API), Drug Development, Bio-Conjugation, various biopharmaceutical, as well as agricultural chemistry.
• Successful achievements in synthesis of various normal and deuterated heterocyclic compounds of medicinal relevance, successful synthesis of Nucleoside, D6-Maribavir, an anti-Viral Agent, total synthesis of Dapsone-D4 for skin disorder, Ritrepinib- D5 anticancer compounds, Ivacapfor-D4, for lung diseases, recently achieve the total synthesis of Capmatinib M18 Metabolite, anti-Cancer agent. All synthesized with high purity,97-99% for pharmaceutical clients, successful synthesis of Cardivolol – D-4
• Successful achievements in synthesis development and designed best efficient new efficient normal and Scale-up synthetic routes of anti- cancer, antiviral, anti-cardiac agents, which are various complex heterocyclic Alkaloids, Beta-Lactams, Carbapenem, Natural Products such as Steroids, Terpenes Di-and Triterpenes, Amino Acid Derivatives, Peptidomimetics, Carbohydrates and Glycoconjugates, synthesis of Nucleic Acid Derivatives.

• Experienced and achieved manipulation of air sensitive compounds, the use of organometallics such as Rhodium, Cobalt, Palladium and Organosilicon for synthesis of various compounds. Use of palladium complex reagents to carry Heck, Suzuki, Stile, Sonogashira cross coupling methatesis and intramolecular cyclisation reactions for creation of Carbon-Carbon bond formation for synthesis of various natural product compounds.
• Skills of patent examining applications for scientific inventions conducted search of prior art by using multiple scientific and patent search softwares to determine prior art, patentability or non-patentability of Medicinal Chemistry inventions pertaining to Biotech-Pharma.
• Achieved synthesis and lipido-aminoacids adjuvant to be applied in the combination of adjuvants with a short saccharide or large polysaccharide to construct glyco-amino lipid derivatives.
• Peptide Chemistry : Elaborated the design, chemical synthesis, and structure-function relationships of peptide-mimetics to mimic β-turn conformation of polypeptides and proteins which can have wide applications to vaccines and drug development.