Summary
Overview
Work History
Education
Skills
Publications
Poster Presentations
Work Availability
Hi, I’m

Patrick W. Gutschow

Director Of Assay Development
San Diego,CA

Summary

Dedicated scientific professional with a history of meeting company goals utilizing consistent and organized practices. Skilled in working under pressure and adapting to new situations and challenges to best enhance product performance. Detailed-oriented, organized and dependable candidate successful at managing multiple projects with a positive attitude and willing to take on added responsibilities to meet team goals. To seek and maintain a full-time position that offers professional challenges utilizing interpersonal communication, excellent time management and problem-solving skills. Proficient in using independent decision-making skills and sound judgment to positively impact company success.

Overview

18
years of professional experience
5
years of post-secondary education

Work History

Intrinsic LifeSciences, LLC
La Jolla, CA

Director of Assay Development
05.2016 - Current

Job overview

  • Managed development efforts to expand product catalog of ELISA kits
  • Served as project manager on more than 15 contract research projects including data transfer agreement negotiation, sample management, workflow planning, data integrity, and reporting
  • Principle writer including peer-reviewed publications, NIH grant applications (Phase I and Phase II), marketing material, and whitepapers
  • Manufacturing and quality control of specialty reagents for kit production
  • Oversaw operations and provided corrective feedback to achieve daily and long-term goals
  • Worked closely with organizational leadership and board of directors to guide operational strategy
  • Drafted and distributed reports to assist board members with critical business decisions

Intrinsic LifeSciences, LLC
La Jolla, CA

Scientist II
09.2011 - 05.2016

Job overview

  • Hybridoma antibody production, purification, and ELISA based screening
  • Developed 6 novel competitive and direct ELISA assays for clinical and RUO applications
  • CAP/CLIA laboratory derived test (LDT) validation principles
  • Authored and revised SOPs
  • Established manufacturing and quality control protocols for commercial kit reagents
  • Conducted experiments in laboratory environment for product development purposes
  • Performed complex troubleshooting and assisted in leading initiatives to solve challenging scientific problems with assays
  • Simultaneously managed several complex projects, meeting all pertinent milestones

Rancho Tissue Technologies, Inc
Rancho Santa Fe, CA

Research Associate
01.2009 - 05.2011

Job overview

  • Combined current literature research with prior colleague data to establish aseptic culture protocols for initiation, multiplication, and rooting of horticulture plants
  • Managed media database and weekly media production

Dr. David Traver, UCSD
SAN DIEGO, CA

Staff Research Associate
09.2007 - 08.2008

Job overview

  • Designed, cloned, and expressed fusion proteins in vitro
  • Managed and manipulated cell culture lines
  • Screened cDNA library via in situ hybridization for novel markers of hematopoietic lineage
  • Independently executed and optimized experimental procedures
  • Performed research into study topics to increase knowledge and to provide valuable contributions
  • Participated in lab meetings and project presentations
  • Recorded and analyzed data to produce reports of results

Dr. David Traver, UCSD
SAN DIEGO, CA

Master's Degree Program
07.2005 - 09.2007

Job overview

  • Developed recombineering-based strategy to clone large promoter elements used to drive reporter fluorophores in transgenic zebrafish lines
  • Analyzed stable transgenic lines with fluorescence microscopy and RT-PCR
  • Performed sequence analysis using bioinformatics tools (e.g
  • BLAST, Sequencer)
  • Managed time efficiently in order to complete all tasks within deadlines
  • Self-motivated, with strong sense of personal responsibility

Education

University of California - San Diego
La Jolla, CA

Master of Science from Biology
07.2006 - 12.2007

University Overview

GPA: 3.96

  • Thesis: A Zebrafish Transgenic Model to Study Antigen Presentation

University of California - San Diego
La Jolla, CA

Bachelor of Science from Molecular Biology
08.2002 - 06.2006

University Overview

GPA: 3.55

  • Sigma Chi Member

Skills

Interpersonal communication and teamwork skills developed through group collaboration

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Publications

  • Gutschow P, Han H, Olbina G, et al. Clinical Immunoassay for Human Hepcidin Predicts Iron Deficiency in First-Time Blood Donors. J Appl Lab Med. 2020 Sep 1;5(5):943-953.
  • Heeney MM, Guo D, De Falco L, Campagna DR, Olbina G, Kao PP, Schmitz-Abe K, Rahimov F, Gutschow P, et al. Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency. Blood. 2018 Jul 26;132(4):448-452.
  • Gutschow P, Schmidt PJ, et al. Competitive enzyme linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis. Haematologica. 2015; 100(2): 167-177.
  • Valerie Wittamer, Julien Y Bertrand, Patrick W Gutschow, David Traver. Characterization of the mononuclear phagocyte system in zebrafish. Blood. 2011;117(26): 7126-7135.

Poster Presentations

  • Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, et al. Development and Early Validation of a New Competitive ELISA Highly Specific for Murine Hepcidin-1 in Serum and Urine. Poster session presented at: Bio-Iron 2013. Fifth Congress of the International Bioiron Society. 2013 April 14-18; London, England.
  • Gutschow P., Westerman K., Han H., et al. Validation of the Intrinsic Hepcidin IDx™ Test, an LDT for Clinical Hepcidin Assessment. Poster session presented at: ASH 2016. 58th Annual Conference of the American Society of Hematology; 2016 Dec 3-6; San Diego, CA.
  • Huiling Han, MD, Keith Westerman, BS, Vaughn Ostland, PhD, Patrick Gutschow, MS, et al. A Novel Dual Monoclonal Sandwich ELISA for Human Erythroferrone. Poster session presented at: ASH 2016. 58th Annual Conference of the American Society of Hematology; 2016 Dec 3-6; San Diego, CA.
  • Patrick Gutschow, MS, Huiling Han, MD, Gordana Olbina, PhD, et al. A Novel Sandwich ELISA to Quantify Erythroferrone in Mouse Serum. Poster session presented at: ASH 2019. 61st Annual Conference of the American Society of Hematology; 2019 Dec 7-10; Orlando, FL.
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Patrick W. GutschowDirector Of Assay Development