Prashant Prabhakar Patil

Accomplished research professional specializing in antibiotic resistance and experimental design. Led projects that advanced understanding of Pseudomonas aeruginosa resistance mechanisms, contributing to scientific progress. Expertise in molecular microbiology, immunology, and high-throughput workflows enhances collaboration on public health initiatives.

• Supervised graduate and undergraduate trainees in microbiology, molecular biology and genomics at NIAID and CSIR-IMTECH.
• Guest lecturer in microbial genomics, genomic epidemiology and antimicrobial resistance evolution at Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh.
• Assisted in organization in workshops related to genomic workflows for whole genome sequencing of bacteria and genomic data analysis.

• American Association for the Advancement of Science (AAAS)
• American Society for Microbiology (ASM)
• Active reviewer for scientific journals PLOS ONE, BMC Genomics, Microbiology Spectrum, Microbiology Resource Announcements, Scientific reports, Infection genetics and Evolution, Frontiers in Microbiology, Frontiers in Cellular and Infection Microbiology

• Contribution of MexVW to β-lactam resistance in P. aeruginosa, ASM Microbe 2023, Houston, USA
• Phylogenomics of Stenotrophomonas maltophilia, Bergey’s Society Meeting, Pune, India 2016
• Genomics of Burkholderia cepacia complex isolates from India, ECCMID 2017, Vienna, Austria

• Microbiology: Cultivation and characterization of aerobic/anaerobic pathogens, antimicrobial susceptibility testing, clinical microbiology methods.
• Molecular Biology: Genetic manipulation, qPCR/ddPCR, sequencing, site-directed mutagenesis, gene expression studies.
• Genomics: Illumina library prep, bacterial WGS and transcriptomics, RNA-Seq, comparative genomics, phylogenetics.
• Bioinformatics: SNP calling, genome assembly/annotation, resistome/virulome analysis, population structure analysis.

• 2017, Travel grant for 27th Congress of Clinical Microbiology and Infectious Diseases (ECCMID2017) at Vienna, Austria, Science and Engineering Research Board (SERB), India
• 2012, Junior Research Fellowship, University Grants Commission, India
• 2012, Junior Research Fellowship, Indian Council of Medical Research (offered, not availed)

• MexVW-OprM efflux pump contributes to resistance to combinations of cephalosporin antibiotics and beta-lactamase inhibitors in the clinical Pseudomonas aeruginosa isolates, Patil PP, Ramkumar A, Ghosh S, Chiang AD, Dekker JP, 2025, Under preparation
• High Resolution Cryo-EM structure of the Pseudomonas aeruginosa OprM Multidrug efflux protein provides the target for rational inhibitor design, Ratliff AC, Putti AM, Patil PP
• Ramkumar A, Botos I, Ghirlando R, Dekker JP and Buchanan SK, 2025, Under preparation
• Hypermutator strains of Pseudomonas aeruginosa reveal novel pathways of resistance to combinations of cephalosporin antibiotics and beta-lactamase inhibitors, Chiang AD
• Patil PP
• Beka L, Youn JH, Launay A, Bonomo RA, ... Dekker JP, 2022, Published
• Global transcriptome analysis of Stenotrophomonas maltophilia in response to human body temperature, Patil PP, Kumar S, Kaur A, Midha S, Bansal K, Patil PB, 2021, Published
• Taxonogenomics reveals novel genomospecies within Stenotrophomonas maltophilia, Patil PP, Midha S, Kumar S, Gautam V, Patil PB, 2018, Published
• Genomics reveals a unique clone of Burkholderia cenocepacia harboring an excising genomic island, Patil PP, Mali S, Midha S, Gautam V, Dash L, Kumar S, Shastri J, Singhal L, Patil PB, 2017, Published