Qinrui Li

• Second prize in clinical skill competition for resident doctors in Beijing.
• Outstanding Fellowship Doctor Award of Peking University in 2024.
• Second Prize in Case Competition of Beijing Association Against Epilepsy, 2024

• Beijing Association Against Epilepsy
• Beijing Society for Neuroscience
• Academic Secretary of Tuberous Sclerosis and Rare Diseases Committee of the China Association Against Epilepsy

1. Li Q, Gu Y, Liang J, Yang Z, Qin J. A long journey to treat epilepsy with the gut microbiota. Frontiers in Cellular Neuroscience. 2024, 1Li Q, Xu Z, Qin J, Yang Z. Epilepsy and Developmental Delay in Pediatric Patients With PTEN Variants and a Literature Review. Pediatr Neurol. 2025 Feb;163:35-44.

• Li Q, Fu N, Han Y, Qin J. Pediatric Autoimmune Encephalitis and Its Relationship with Infection. Pediatric Neurology. 2021, 120: 27-32.
• Li Q, Liang J, Fu N, Han Y, Qin J. A Ketogenic Diet and the Treatment of Autism Spectrum Disorder. Frontiers in Pediatrics. 2021, 9: 650624.
• Li Q, Liang F, Liang W, Shi W, Han Y. Prevalence of Anemia and Its Associated Risk Factors Among 6-Months-Old Infants in Beijing. Frontiers in Pediatrics. 2019, 7: 286.
• Li Q, Han Y, Du J, Jin H, Zhang J, Niu M, Qin J. Recombinant Human Erythropoietin Protects Against Hippocampal Damage in Developing Rats with Seizures by Modulating Autophagy via the S6 Protein in a Time-Dependent Manner. Neurochemical Research. 2018, 43(2): 465-476.
• Li Q, Han Y, Du J, Jin H, Zhang J, Niu M, Qin J. Recombinant human erythropoietin protects against brain injury through blunting the mTORC1 pathway in the developing brains of rats with seizures. Life Sciences. 2018, 194: 15-25.
• Li Q, Han Y, Du J, Jin H, Zhang J, Niu M, Qin J. Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: Changes in LC3, P62, Beclin-1 and Bcl-2 levels. Neuroscience Research. 2018, 130: 47-55.
• Li Q, Han Y, Dy A, Hagerman RJ. The Gut Microbiota and Autism Spectrum Disorders. Frontiers in Cellular Neuroscience. 2017, 11: 120.
• Li Q, Han Y, Qin J et al. Changes of autophagy-related genes in the brains of the rats in the developmental stage with epilepsy. Chinese journal of applied clinical pediatrics. 2018, 33(12): 909-912.
• Li Q, Liang F, Liang W, Zhang J, Niu M, Han Y. The Influence of Different Caregivers on Infant Growth and Development in China. Frontiers in Pediatrics. 2017, 5: 243.
• Li Q, Han Y, Du J, Qin J. The gut microbiota and the disease of central nervous system. Progress in Physiological Sciences. 2016 Oct;47(5):365-8.
• Li Q, Han Y, Qin J et al. Phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway and epilepsy. Chinese journal of applied clinical pediatrics, 2015, 30(24): 1915-1917.
• Fu J, Li Q, Zhang GF, Yang ZX, Qin J. Neuropsychiatric disorders in Chinese pediatric tuberous sclerosis complex patients associated with drug-resistant epilepsy: A TAND checklist-based survey. Epilepsy & Behavior Reports. Volume 30. 2025.
• Huang S, Hu C, Zhong M, Li Q, Dai Y, Ma J, Qin J, Sun D. Clinical phenotypes of developmental and epileptic encephalopathy-related recurrent KCNH5 missense variant p.R327H in Chinese children. Epilepsy Behavior Reports. 2024 Apr 25;26:100671.
• Zhang B, Qiao J, Li Q, Luan G, Qin J. Astrocyte-derived complement C3 is activated in patients with tuberous sclerosis complex and mediates immune injury: an integrated bioinformatics analysis. Translational Pediatrics. 2023 Jun 30;12(6):1098-1109.
• An Y, Zhang Y, Zhang YJ, Cui Y, Liang J, Li Q, Fu J, Fu N, Chen Y, Yang Y, Qin J. Prognosis of childhood adrenoleukodystrophy with cognitive disorder after haploidentical allogenic hemato-poietic stem cell transplantation. Chinese journal of applied clinical pediatrics. 2023, 38(08):566-570.
• Wei C, Guo C, Li Q, Ye L. A family of hereditary protein S deficiency with the onset of pulmonary embolism and literature review. Chinese Journal of Pediatrics. 2022,60(02): 134-138.
• Shu L, Xiao N, Qin J, Tian Q, Zhang Y, Li H, Liu J, Li Q, Gu W, Wang P, Wang H, Mao X. The Role of Microtubule Associated Serine/Threonine Kinase 3 Variants in Neurodevelopmental Diseases: Genotype-Phenotype Association. Frontiers in Molecular Neuroscience. 2022 Jan 12;14:775479.
• Niu M, Li Q, Zhang J, Wen F, Dang W, Duan G, Li H, Ruan W, Yang P, Guan C, Tian H, Gao X, Zhang S, Yuan F, Han Y. Characterization of Intestinal Microbiota and Probiotics Treatment in
• Zhang J, Han Y, Zhao Y, Li Q, Jin H, Qin J. Inhibition of TRIB3 Protects Against Neurotoxic Injury Induced by Kainic Acid in Rats. 2019 May 22;10:585.
• Zhang J, Han Y, Zhao Y, Li Q, Jin HF, Du JB, Qin J. Role of endoplasmic reticulum stress-associated gene TRIB3 in rats following kainic acid-induced seizures. International journal of clinical and experimental pathology. 2019 Feb 1;12(2):599-605.
• Niu M, Han Y, Li Q, Zhang J. Endogenous sulfur dioxide regulates hippocampal neuron apoptosis in developing epileptic rats and is associated with the PERK signaling pathway. Neuroscience Letters. 2018 Feb 5;665:22-28.
• Niu M, Han Y, Dy ABC, Du J, Jin H, Qin J, Zhang J, Li Q, Hagerman RJ. Fragile X Syndrome: Prevalence, Treatment, and Prevention in China. Frontiers in Neurology. 2017 Jun 6;8:254.
• Niu M, Han Y, Dy ABC, Du J, Jin H, Qin J, Zhang J, Li Q, Hagerman RJ. Autism Symptoms in Fragile X Syndrome. Journal of Child Neurology. 2017 Sep;32(10):903-909.
• Zhao Y, Han Y, Bu D, Zhang J, Li Q, Jin H, Du J, Qin J. Reduced AKT phosphorylation contributes to endoplasmic reticulum stress-mediated hippocampal neuronal apoptosis in rat recurrent febrile seizure. Life Sciences. 2016 May 15;153:153-62.

• The molecular mechanisms of brain injury associated with mTORopathies in children.
• The mechanisms of autism spectrum disorder (ASD) and develop molecular therapies for human neurodevelopmental disorders caused by genetic diseases (TSC or PTEN).
• Focuses on developing novel imaging and blood/CSF-based biomarkers of CNS neuroimmunological disorders including autoimmune encephalitis.

• National Natural Science Foundation of China, 82101516, The mechanisms of mTORC1 pathway regulating brain injury induced by recurrent seizures through p62 protein.
• Peking University People's Hospital research and development Fund, The Mechanisms of 3-acetamidocoumarin in improving TSC-associated neuropsychiatric disorders through activation of TFEB mediated autophagy lysosome pathway.