Rahul Dev Jana

Accomplished researcher with expertise in multi-step synthesis and drug development, honed at the University of Houston. Proven ability to design biocompatible catalysts and fluorescent probes, enhancing real-time tracking of chemical reactions. Strong analytical skills complemented by effective collaboration in multidisciplinary teams, driving innovative solutions in metallodrug engineering and environmental remediation.

• CSIR Fellowship, All India Rank 10 for doctoral research through the CSIR-UGC National Eligibility Test (NET), 2023
• Best Poster Award in Chemistry, 2018, Indian Association for the Cultivation of Science
• Ranked 27th (All India) in Chemistry, Joint Admission Test for M. Sc (JAM 2012), IITs, India, 2012

• Selective Iridium-Catalyzed Reductive Amination Inside Living Cells, Jana, R. D.; Nguyen, H. D.; Loi, L. H., 2025, manuscript under preparation
• Reversing Signs of Parkinsonism in a Cell Model Using Mitochondria-Targeted Organoiridium Catalysis, Jana, R. D.; Nguyen, H. D.; Yan, G.; Loi, L. H., J. Med. Chem., 2025, 68, 1970
• Stereoelectronic Tuning of Bioinspired Nonheme Iron(IV)-Oxo Species by Amide Groups, Jana, R. D.; Das, A.; Samanta, R.; Banerjee, S.; Paul, S.; Paine, T. K., Inorg. Chem., 2024, 63, 21042
• Understanding structural isomerism in organoiridium picolinamidate complexes, Nguyen, H. D.; Laconsay, C. J.; Jana, R. D.; Ganguly, T.; Hoang, S. T.; Kaushal, K.; Wu, J. I.; Loi, L. H., Inorg. Chem. Front., 2024, 11, 7407
• Organoiridium Complexes Enhance Cellular Defense Against Reactive Aldehydes Species, Jana, R. D.; Ngo, A. H.; Bose, S.; Loi, L. H., Chem. -Eur. J., 2023, 29, e202300842
• Lewis Acid-Driven Self-Assembly of Diiridium Macrocyclic Catalysts, Nguyen, H. D.; Jana, R. D.; Campbell, D. T.; Tran, T. V.; Loi, L. H., Chem. Sci., 2023, 14, 10264
• Aliphatic C-H Bond Halogenation by Iron Catalysts, Jana, R. D.; Paine, T. K., 2022, for Wiley-VCH entitled 'Handbook of C-H Functionalization'
• Dioxygen Activation and Mandelate Decarboxylation by Iron(II) Complexes, Jana, R. D.; Chakraborty, B.; Paria, S.; Ohta, T.; Singh, R.; Mandal, S.; Paul, S.; Itoh, S.; Paine, T. K., Inorg. Chem., 2022, 61, 10461
• Enhancing Chemo- and Stereoselectivity in C–H Bond Oxygenation with H2O2, Jana, R. D.; Das, A.; Paine, T. K., Inorg. Chem., 2021, 60, 5969
• Oxidative Degradation of Toxic Organic Pollutants by Water Soluble Nonheme Iron(IV)-Oxo Complexes, Munshi, S.; Jana, R. D.; Paine, T. K., Dalton Trans., 2021, 50, 5590
• Tuning the Stereoelectronic Factors of Iron(II)-2-Aminophenolate Complexes, Chatterjee, S.; Banerjee, S.; Jana, R. D.; Bhattacharya, S.; Chakraborty, B.; Jannuzzi, S. A. V., Dalton Trans., 2021, 50, 1901
• Oxidative C–N Bond Cleavage of (2-Pyridylmethyl)amine-Based Tetradentate Supporting Ligands, Chakraborty, B.; Ghosh, I.; Jana, R. D.; Paine, T. K., Dalton Trans., 2020, 49, 3463
• Oxidizing Ability of a Dioxygen-Activating Nonheme Iron (II)-Benzilate Complex, Sheet, D.; Bera, A.; Jana, R. D.; Paine, T. K., Inorg. Chem., 2019, 58, 4828
• Aliphatic C–H Bond Halogenation by Iron(II)-α-Keto Acid Complexes and O2, Jana, R. D.; Sheet, D.; Chatterjee, S.; Paine, T. K., Inorg. Chem., 2018, 57, 8769
• Reductive Activation of O2 by Non-Heme Iron(II) Benzilate Complexes of N4 Ligands, Chakraborty, B.; Jana, R. D.; Singh, R.; Paria, S.; Paine, T. K., Inorg. Chem., 2017, 56, 359
• Efficient and Simple Approaches Towards Direct Oxidative Esterification of Alcohols, Ray, R.; Jana, R. D.; Bhadra, M.; Maiti, D.; Lahiri, G. K., Chem. -Eur. J., 2014, 47, 15618
• Sensitivity of a Strained C–C Single Bond to Charge Transfer, Mondal, P.; Agarwala, H.; Jana, R. D.; Plebst, S.; Grupp, A.; Ehret, F.; Mobin, S.; Kaim, W.; Lahiri, G. K., Inorg. Chem., 2014, 53, 7389

• Prof. Loi H. Do, Department of Chemistry, University of Houston, Houston, Texas, 77004, (+1) 713-743-0373, lhdo@central.uh.edu
• Prof. Tapan Kanti Paine, School of Chemical Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata, 700032, India, (+91) 33 2473 4971, ictkp@iacs.res.in
• Prof. Goutam Kumar Lahiri, Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India, 022-2576 7159, lahiri@chem.iitb.ac.in

• Reversing Signs of Parkinsonism in a Cell Model Using Mitochondria-Targeted Organoiridium Catalysis, Jana, R. D.; Nguyen, H. D.; Yan, G.; Loi, L. H., Gordon Research Conference on Metals in Medicine, New Hampshire, United States, 06/01/24, Poster Preview Talk and Poster
• Enhancing Chemo- and Stereoselectivity in C–H Bond Oxygenation with H2O2, Jana, R. D.; Das, A.; Paine, T. K., Indo-French Symposium, Kolkata, India, 11/01/19, Poster
• Dioxygen Activation and Mandelate Decarboxylation by Iron(II) Complexes, Jana, R. D.; Chakraborty, B.; Paria, S.; Ohta, T.; Singh, R.; Mandal, S.; Paul, S.; Itoh, S.; Paine, T. K., Frontier in Inorganic Chemistry- II, Kolkata, India, 03/01/18, Poster
• Aliphatic C–H Bond Halogenation by Iron(II)-α-Keto Acid Complexes and O2, Jana, R. D.; Sheet, D.; Chatterjee, S.; Paine, T. K., 19th CRSI National Symposium in Chemistry, Siliguri, India, 07/01/16, Poster

Multi-step synthesis, Drug Development, Fluorescent probes synthesis, Solvent extraction, Column chromatography, Recrystallization, Distillation, Filtration, Cell culture, Biochemical assay design, Fluorescence microscopy, Protein isolation, Gas Chromatography-Mass Spectrometry (GC-MS), High-Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Microplate Reader, Cyclic Voltammetry (CV), Mass Spectrometry (ESI-MS), Magnetic Susceptibility Measurements, Single Crystal X-ray Diffraction (XRD), Nuclear Magnetic Resonance Spectroscopy (NMR), Diode-array UV-Vis, Fluorescence Spectroscopy, Infrared Spectroscopy (IR), Electron Paramagnetic Resonance Spectroscopy (EPR), Mössbauer Spectroscopy, Raman Spectroscopy, GraphPad Prism, MestreNova, MassLynx, Bruker AXS, Apex 3, Olex2-1.3, Xshell, Platon, Topspin 3.2, MestRec, CW-ESR, ChemDraw, Chem3D, Mercury, Ortep, Origin, ImageJ, Corel Draw, Adobe Illustrator, Microsoft Excel, SciFinder, Reaxys, Google Scholar, Endnote

• Postdoctoral Associate, University of Houston, Department of Chemistry, Houston, Texas, 08/01/21, Present, Prof. Loi H. Do, Developed biocompatible iridium catalysts for organic transformation reactions., Investigated structure-activity relationships (SAR) and mechanisms of action., Designed and synthesized fluorescent probes for real-time tracking of metal catalysts., Performed biochemical assays to assess the impact of catalysts on biomarkers., Quantified intracellular reaction products using biochemical tools., Conducted metal-catalyzed chemical reactions on protein backbones.
• Graduate Chemistry Research Assistant, Indian Association for the Cultivation of Science (IACS), Kolkata, West Bengal, India, 08/01/14, 05/01/21, Prof. Tapan Kanti Paine, Designed, synthesized, and characterized transition-metal complexes., Investigated small molecule activation by transition metal complexes., Trapped and characterized reactive intermediates spectroscopically., Developed mono- and multi-metallic 3d transition metal catalysts., Applied biomimetic metal complexes to degrade organic pollutants., Contributed to the development of synthetic methodologies.
• MS Project in Chemistry, Indian Institute of Technology (IIT)-Bombay, Bombay, Maharashtra, India, 08/01/13, 05/01/14, Prof. Goutam Kumar Lahiri, Synthesized and analyzed redox non-innocent ruthenium complexes., Investigated electron transfer mechanism in metal complexes., Developed efficient approaches for oxidative esterification of alcohols.