Riddhi Chawla

• Investigating therapeutic effect of a test compound (Cemdomespib) on neuromuscular junction (NMJ) innervation and myelination in a Charcot-Marie-Tooth disease mouse model
• Modified and optimized immunohistochemistry protocols for enhanced assay precision
• Conducted tissue processing, including fixation, sectioning on cryostat, and immunostaining, to assess drug effects on NMJs; performed nerve sectioning using Leica UC6 ultramicrotome and qualitative and quantitative nerve morphology analysis using light microscope
• Applied electron microscopy staining techniques to study axon and Schwann cell structures
• Performed data analysis using Image J and Fiji software
• Gained experience in cell culture maintenance, mitochondrial function analysis (Seahorse assay), and protein expression (Western blot analysis)

• Investigating therapeutic effect of test compound’s (Cemdomespib) impact on neuromuscular junction (NMJ) innervation and myelination in a Charcot-Marie-Tooth disease mouse model
• Modified and optimized immunohistochemistry protocols for enhanced assay precision
• Conducted tissue processing, including fixation, sectioning on cryostat, and immunostaining, to assess drug effects on NMJs; performed nerve sectioning using Leica UC6 ultramicrotome and qualitative and quantitative nerve morphology analysis using light microscope
• Applied electron microscopy staining techniques to study axon and Schwann cell structures
• Performed data analysis using Image J and Fiji software
• Gained experience in cell culture maintenance, mitochondrial function analysis (Seahorse assay), and protein expression (Western blot analysis)

• Antibiotic Stewardship and Usage Review: Oversaw rational antibiotic use across various settings, including surgical prophylaxis and medical prevention, reporting more than 60 non-compliance
• Targeted Antibiotic Selection and Management: Implemented culture and sensitivity-based reviews and reserved antibiotic regulations to ensure effective treatment and minimize resistance
• Transition and Optimization of Antibiotic Therapy: Assessed and optimized transitions from IV to oral antibiotic therapies, focusing on patient comfort and cost-effectiveness
• Monitoring for Drug Safety and Efficacy: Vigilantly tracked 14 adverse drug reactions and continuously assessed medication impacts to uphold drug safety and patient care standards
• Strengthened communication skills through regular interactions with other professionals

• Executed in-depth analysis of standard pharmacological treatments by reviewing 150-200 prescriptions to ensure efficacy and safety
• Proactively identified and resolved 12 medication-related complications, encompassing drug interactions and adverse effects along with comprehensive documentation
• Provided personalized counseling to patients, developing tailored care plans to meet individual health needs
• Diligently documented comprehensive patient histories, including medical, medication, social, familial, and allergic information
• Collaborated effectively in multidisciplinary ward rounds with physicians, contributing to integrated patient care

• Led Prescription Audit Trials (PAT) during clinical ward rounds, ensuring optimal medication management by reviewing 20-30 prescriptions daily
• Conducted detailed reviews of patient medication records to validate suitability of prescribed therapies
• Designed and implemented medication regimens aimed at minimizing risk of side effects
• Provided guidance on pharmacological choices and emergency equipment for critical care scenarios, including ’code blue’ events
• Completed comprehensive CPR training and contributed to projects such as “Antibiotic Stewardship Program” and “Error Reporting” initiative
• Acquired knowledge of chemotherapy preparation techniques and protocols

• Led Gujarat’s first hospital-based epilepsy study at GMERS Medical College over 6 months, involving 102 pediatric patients, focusing on parent knowledge and behavior towards Antiepileptic Drugs (AEDs)
• Developed and Implemented Custom Questionnaire: Created and utilized 25-item questionnaire for data collection
• Uncovered Key Insights in Epilepsy Awareness: Revealed that only 5.8% of parents correctly identified epilepsy as brain disorder, indicating significant knowledge gaps
• Demonstrated High Patient Compliance: Found that 59.78% of caretakers consistently administered epilepsy medications, highlighting effective treatment adherence
• Pioneered Regional Healthcare Research: Conducted Gujarat’s first hospital-based study on epilepsy, focusing on parent knowledge and behavior towards Antiepileptic Drugs (AEDs)
• Gathered and organized information for research purposes.