Russell Hoover
Vertex Pharmaceuticals
Harvard,MA
28
years of professional experience
Skilled researcher with strong background in scientific inquiry and data analysis. Known for effective team collaboration and consistently achieving impactful results. Expertise in experimental design, statistical modeling, and academic writing. Adaptable and reliable, with proven track record of meeting evolving project needs.
Work History
Senior Research Fellow
24 Years 1 Month- Spearheaded multiple research projects focused on small molecule cancer drugs, including the clinical candidate VX-984, a first in class DNA-PK inhibitor for radiotherapy
- Led the Biology efforts for both a preclinical lead op and a clinical stage program. The latter led to the clinical candidate VX-864, the first small molecule to correct a mutant secreted protein, AAT
- Managed a number of collaborations with CROs and academia, interacted with cross-functional teams including clinical and development, and am familiar with IND preparation. I'm an inventor featured on two patents: US 20190322673 A1 and US 20190322658 A1.
Postdoctoral Researcher - George Daley Lab
3 Years 6 Months- Investigated signaling pathways involved in BCR/ABL mediated transformation to understand mechanisms of oncogenesis
- Ran an HTS screen searching for inhibitors of STAT5
- Studied the effects of farnesyl transferase inhibitors and Gleevec on leukemic cells
- Taught a seminar class at MIT focused on the molecular targeting of cancer
Education
Ph.D. - Cell And Molecular Biology
Skills
Skilled in cell culture
Laboratory techniques
Strong research design
Experimental design
Cell line development
IND submission
Laboratory techniques
Advanced data analysis
Research methods
Innovative problem-solving
Critical thinking
Timeline
Senior Research Fellow
Vertex Pharmaceuticals
02.2002 - 03.2026Read More
Postdoctoral Researcher - George Daley Lab
Whitehead Institute for Biomedical Research
08.1998 - 02.2002Read More
Pennsylvania College of Medicine
Ph.D. from Cell And Molecular Biology
Read More
Publications
For a full list visit https://pubmed.ncbi.nlm.nih.gov/?term=rr+hoover