Safir Ullah Khan

Experienced in cancer signaling and therapeutic response, with expertise in immuno- and chemotherapy-related wet lab techniques. Proficient in applying machine learning for drug design and discovery, large-scale bioinformatics analyses, and BioPython programming.

• Scientific Research Associate, Moores Cancer Center, UC San Diego, USA, 2024-01-01, 2025-12-31, Staff research associate working on Advancing gynecologic oncology research: Genomics, chemotherapy, and data science integration in the laboratory of cancer immune and chemotherapy.
• Extramural Researcher, Moores Cancer Center, UC San Diego, USA, 2023-01-01, 2024-12-31, Visiting Student learning wet lab techniques for studying Breast Cancer in the laboratory of Solid Tumor Program.
• Graduate Researcher, CINVESTAV-IPN, Mexico City, MX, 2020-01-01, 2023-12-31, Calcium sensing receptor mediates cellular migration and invasion in metastatic Breast Cancer Cells, via the Gα and Gβγ-PI3K/PKC-ζ signaling pathway.
• Masters Research, Arid University, Rawalpindi and Hazara University, Mansehra, PK, 2013-01-01, 2018-12-31, Analysis of regulatory systems; An earlier and age related occurrence of diabetes, hypertension and related cardiovascular disease. Collaborative Masters project: NanoMed: exploring the therapeutic potential of nanomedicines for disease treatment and their impact.

• 2020-2023, Conacyt Mexico PhD Scholarship
• 2017, Higher Education Commission Pakistan, Research Grant

• Research development and protocols, Department of Biology, University of Madrid, Spain, 2021-11-23, 2022-09-20
• Biomedical Microscopy, University of Bucharest, Romania, 2022-02-14, 2022-05-29
• Interdisciplinary Approaches to scientific research, Autonomous University of Madrid, Spain, 2022-01-18, 2022-03-29
• Advances and Perspectives of the Nanoworld, Mexico City, Mexico, 2022, Symposium
• Cell Culture Techniques, Autonomous University of Mexico City, Mexico, 2019, Symposium
• Smoking Related Environmental Hazards, Islamabad, Pakistan, 2016, Symposium
• Factors and Lifestyle in breast tumorigenesis, Nuclear Medicine Oncology & Radiotherapy Institute (NORI), Islamabad, Pakistan, 2016, Symposium

• Khan, Safir Ullah, Rodolfo Daniel Cervantes-Villagrana, Jorge Eduardo del Río-Robles, Janik Adriana Tomás-Morales, Yazmin Torres-Santos, José Vázquez-Prado, Guadalupe Reyes-Cruz, Calcium sensing receptor stimulates breast cancer cell migration and invasion via protein kinase C ζ., Experimental Cell Research, 447, 2, 2025, 114523
• Khan, Safir Ullah, Zahid Ullah, Hadia Shaukat, Shiza Unab, Saba Jannat, Waqar Ali, Amir Ali, Muhammad Irfan, Muhammad Fiaz Khan, Rodolfo Daniel Cervantes-Villagrana, TP53 and its Regulatory genes as prognosis of cutaneous melanoma., Cancer Informatics, 22, 2023, 11769351231177267
• Javid M, Khan SU, Akram M, Cervantes-Villagrana RD, Rafi M, Khan MF, Raza Rizvi SS, Higher cortisol level and reduced circulating triiodothyronine in patients with cardiovascular diseases: A case-control study., JRSM Cardiovascular Disease, May, 2025, 14, 20480040251340609
• Khan, Safir Ullah, Karla Daniela Hernández-González, Amir Ali, Syed Shakeel Raza Rizvi, Diabetes and the fabkin complex: A dual-edged sword., Biochemical Pharmacology, 2024, 116196
• Khan, Safir Ullah, Saba Jannat, Hadia Shaukat, Shiza Unab, Tanzeela, Maleeha Akram, Muhammad Nasir Khan Khattak, Stress induced cortisol release depresses the secretion of testosterone in patients with type 2 diabetes mellitus., Clinical Medicine Insights: Endocrinology and Diabetes, 16, 2023, 11795514221145841
• Rehman, Nagina, Farhat Jabeen, Muhammad Asad, Aneela Nijabat, Amir Ali, Safir Ullah Khan, Juan Pedro Luna-Arias, Exposure to zinc oxide nanoparticles induced reproductive toxicities in male Sprague Dawley rats., Journal of Trace Elements in Medicine and Biology, 83, 2024, 127411
• Aravinth, Annamalai, Sundaramoorthy Dhanasundaram, Pachiappan Perumal, Chinnaperumal Kamaraj, Safir Ullah Khan, Amir Ali, Chinnasamy Ragavendran, Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus., Experimental Parasitology, 256, 2024, 108651
• Kamaraj, C., Ragavendran, C., Prem, P., Naveen Kumar, S., Ali, A., Kazmi, A., Ullah, A., Chandra Satish Kumar, R., Khan, S.U., Luna-Arias, J.P., Mashwani, Z.U.R., Exploring the therapeutic potential of traditional antimalarial and antidengue plants: a mechanistic perspective., Canadian Journal of Infectious Diseases and Medical Microbiology, 2023, 1860084
• Ali, Amir, Zia-ur-Rehman Mashwani, Ilyas Ahmad, Naveed Iqbal Raja, Sher Mohammad, Safir Ullah Khan, Plant in vitro cultures: A promising and emerging technology for the feasible production of antidiabetic metabolites in Caralluma tuberculata., Frontiers in Endocrinology, 13, 2022, 1029942
• Murugesan, S., Ragavendran, C., Ali, A., Arumugam, V., Lakshmanan, D.K., Palanichamy, P., Venkatesan, M., Kamaraj, C., Luna-Arias, J.P., Fabián, F.L., Khan, S.U., Screening and druggability analysis of Marine active metabolites against SARS-CoV-2: an Integrative Computational Approach., International Journal of Translational Medicine, 3, 1, 2022, 27-41
• Alyas, J., Rafiq, A., Amir, H., Khan, S.U., Sultana, T., Ali, A., Hameed, A., Ahmad, I., Kazmi, A., Sajid, T., Ahmad, A., Human insulin: history, recent advances, and expression systems for mass production., Biomedical Research and Therapy, 8, 9, 2021, 4540-4561