Sasya Madhurantakam
Dallas,USA
Summary
I possess a strong passion for advancing disease detection and specialize in developing electrochemical biosensors. My expertise lies in synthesizing nanomaterials and creating in vitro cell-based assays to monitor and stratify diseases based on biomarker levels. My ultimate goal is to facilitate early, on-site detection of diseases, making a substantial and positive impact on the field of disease detection. My unwavering dedication to this field is a testament to my exceptional commitment to achieving my goals. With my experience and skills, I am confident in my ability to significantly contribute to the field of disease detection. I remain steadfast in my unwavering efforts to revolutionize disease detection and believe my expertise and experience will enable me to make a significant contribution to the world.
Overview
11
11
years of professional experience
Work History
Research Scientist
The University of Texas at Dallas
Dallas, United States
09.2023 - Current
- Development of rapid and point-of-care devices for tracking of disease status based on biomarker levels
- Early onsite detection of Infections using independently developed biosensor prototypes
- Automated liquid handling systems for lab-to-fab biosensor design and manufacturing, along with quality control and tracking of fabricated sensors
- Reviewed project activities, and prepared and reviewed research, testing, and operational reports.
- Thrives in a fast-paced, startup environment- Identified potential problems and developed solutions related to research projects.
- Demonstrate strong project management skills - trained undergraduate, master, and PhD students
- Maintained field equipment and performed troubleshooting techniques to keep tools fully operational with clear DOEs and SOPs
- Experience in handling immunoassays in clinical settings and GLP requirements
- Experience in submitting internal review boards for clinical human sample handling and medical devices
Post-Doctoral Research Associate
The University of Texas at Dallas
Dallas, United States
04.2021 - 08.2023
- Designed protocols for manufacturing sensor devices
- Supervised undergraduate students in their research projects and guided experimental techniques
- Identified and resolved data issues to drive accuracy and integrity
- Contributed to high-impact publications through diligent data analysis and interpretation
- Enhanced research outcomes by implementing cutting-edge experimental techniques and methodologies
- Optimized laboratory processes, resulting in increased efficiency and reduced costs
- Developed novel experimental protocols tailored to specific research objectives
- Designed research protocols to perform instrumentation relative to research procedures
- Managed day-to-day lab operations, maintaining a well-organized
- workspace for efficient experimentation
- Reviewed manuscripts for reputable scientific journals, ensuring the publication of high-quality research articles
JSPS Postdoctoral Fellow
Japan Society for the Promotion of
Osaka University and Niigata University, Japan
03.2019 - 03.2021
- Worked on the development of Boron-doped diamond electrodes for the detection of anticancer drugs
- Identified potential problems and developed solutions related to research projects
- Adhered to standards in areas involving data collection, research protocols
- Performed literature reviews to stay up-to-date on current developments in the field
- Worked on the development of an implantable drug-sensing system that contributes to safe and effective therapy for epilepsy
- Attended meetings with external partners regarding ongoing collaborations
- Contributed to publications in peer-reviewed journals by writing manuscript.
INSPIRE-Senior Research Fellow
Department Of Science And Technology
SASTRA University, Thanjavur, India
09.2015 - 09.2018
- Development of portable electrochemical e for simultaneous detection of biomarkers of Metabolic syndrome
- Designed and maintained databases to store experimental results, analyze trends, and facilitate future research efforts
- Collaborated with other researchers from different departments within the organization to develop more effective strategies for conducting experiments
- Shared research findings through publications, presentations, and conferences.
INSPIRE-Junior Reseacrh Fellow
Department Of Science And Technology
SASTRA University, Thanjavur, India
12.2012 - 08.2015
- Designing experiments for developing electrochemical biosensors
- Synthesis and characterization of nanomaterials
- In-vitro cell culture techniques
- Immuno assays and cell-based assays
- Identified potential problems and developed solutions related to research projects
- Adhered to tool and equipment safety protocols
- Communicated the research findings.
Education
Ph.D. - Electrochemical Biosensors
School of Chemical And Biotechnology
Master of Science - Nanomaterials and Technology
Sri Venkateswara University
M.Sc. - Masters project
Department of Materials Engineering
B.Sc. - Biotechnology
Sri Venkateswara University
Skills
- Electrochemical biosensors
- Synthesis and characterization of nanomaterials
- Immunoassays and cell-based assays
- Data analysis
Conference Presentations
- Participated in health Innovations and point-of-care technologies (HI-POCT) held at Texas A&M University, Houston.
- Participated in 21st National Convention of Electrochemists (NCL-21) held at VIT, Chennai.
- Participated in Neuro-2019 held at Niigata, Japan.
- Presented a poster in ICONSAT-2018 held at IISc, Bangalore (Best poster award)
- Presented a poster in NANAO INDIA held at IIT Delhi, Delhi.
- Presented a poster in ICFNN-2017 held at SASTRA University, Thanjavur.
- Presented a poster in 'Biosensors 2016' organized by Elsevier at Gothia Towers, Sweden.
- Presented a poster in ICFNN-2016 held at SASTRA University, Thanjavur.
- Presented a poster in 'Global cancer summit-2015' held at IISc, Bangalore (Best poster award)
- Presented a poster in the INUP Familiarization workshop held at IISc, Bangalore during May 18- 20, 2015.
- One-day workshop on Advanced materials & their applications organized by BMSIT & LSIKC, Bangalore.
- National conference on latest trends on emerging materials (NCLTEM), JNTUH, Hyderabad.
- NANOMEET-2010 organized by Centre for Nanoscience & Technology, Anna University, Chennai.
Proceedings
Development of electrochemical glucose biosensor for the estimation of cancer cell proliferation, Sasya Madhurantakam, Jayanth Babu K, John Bosco Balaguru Rayappan, Uma Maheswari Krishnan, Procedia Technology, 27 (2017) 226-228
Research Skills
- Synthesis techniques
- Hands-on Experience with Characterization Techniques
- Hands-on Experience with Cell Culture Techniques
- Spin coating, Dip coating
- Hydrothermal methods
- Sol-gel techniques
- Chemical synthesis
- Electrochemical measurements
- Spectroscopic techniques
- Microscopic techniques
- Maintaining cell lines in culture
- Cell based assays
- Extra cellular flux analyzer
- Multimode reader
- ELISA and ELLA
Research Interests
- Synthesis and characterization of nanomaterials
- Electrochemical sensors, microfluidic devices
- Biomedical devices and wearables
Book Chapters
Future perspectives of disposable electrochemical sensors, Sasya Madhurantakam, Jayanth Babu K, K.S. Shalini devi, Disposable Electrochemical Sensors for Health Monitoring: Materials Properties and Design, Royal Society of Chemistry, https://doi.org/10.1039/9781839163364-00432
Awards
- Baxter Young Investigator Award-2022, USA (2nd tier winner)
- Excellent Young Researcher in LEADER program by JSPS
- IIT- Bombay-Metrohm Young Chemist Award -2019 (Rs. 200000/- Cash price)
- JSPS Postdoctoral Fellow (P18411)
- ACS NANO BEST POSTER AWARD (Rs.5000/-cash prize) ICONSAT- 2018 Karnataka DST- Nano Fellowship- Bangalore India Nano-2017(Rs.50,000/- Cash price)
- DST -ITS Travel Grant for attending Biosensors-2016 held at Sweden
- BEST POSTER AWARD in 'Global Cancer Summit -2015
- DST INSPIRE fellow (IF120812)
- University Topper in M.Sc
- College First Rank in B.Sc
- Mandal First rank in Intermediate (92%)
- Mandal First rank in Tenth (86%)
Publications
- Electrochemical Label-free Methods for Ultrasensitive Multiplex Protein Profiling of Infectious Diseases, S Madhurantakam, S Prasad, N Churcher, R Kumar, Current Medicinal Chemistry, 2024, https://doi.org/10.2174/0929867330666230609112052
- Recent Progress in Transition Metal Dichalcogenides for Electrochemical Biomolecular Detection, S Madhurantakam, G Mathew, BE David, A Naqvi, S Prasad, Micromachines, 14 (12), 21392023, https://doi.org/10.3390/mi14122139
- COVID severity test (CoST sensor)-An electrochemical immunosensing approach to stratify disease severity, S Madhurantakam, JB Karnam, S Muthukumar, S Prasad, Bioengineering & Translational Medicine, 8 (5), e105662023, https://doi.org/10.1002/btm2.10566
- Tracking Active Glucose-Galactose [TAGG] dynamics in human sweat, CF Greyling, S Madhurantakam, KC Lin, S Muthukumar, S Prasad, Biosensors and Bioelectronics: X, 14, 10035712023, https://doi.org/10.1016/j.biosx.2023.100357
- A strategy for low-cost portable monitoring of plasma drug concentrations using a sustainable boron-doped-diamond chip, T Saiki, G Ogata, S Sawamura, K Asai, O Razvina, K Watanabe, R Kato, Heliyon, 9 (5)2023, https://doi.org/10.1016/j.heliyon.2023.e15963
- Multiplex sensing of IL-10 and CRP towards predicting critical illness in COVID-19 infections, S Madhurantakam, ZJ Lee, A Naqvi, JB Karnam, S Muthukumar, S Prasad, Biosensors and Bioelectronics: X, 13, 10030732023, https://doi.org/10.1016/j.biosx.2023.100307
- Importance of IP-10 as a biomarker of host immune response: Critical perspective as a target for biosensing, S Madhurantakam, ZJ Lee, A Naqvi, S Prasad, Current Research in Biotechnology, 5, 10013012023, https://doi.org/10.1016/j.crbiot.2023.100130
- Emerging electrochemical biosensing trends for rapid diagnosis of COVID-19 biomarkers as point-of-care platforms: A critical review, S Madhurantakam, S Muthukumar, S Prasad, ACS omega, 7 (15), 12467-12473302022, https://doi.org/10.1021/acsomega.2c00638
- Analysis of Pharmacokinetics in the Cochlea of the Inner Ear, S Sawamura, G Ogata, K Asai, O Razvina, T Ota, Q Zhang, Frontiers in Pharmacology, 12, 63350512021, https://doi.org/10.3389/fphar.2021.633505
- Nano": an emerging avenue in electrochemical detection of neurotransmitters, S Madhurantakam, JB Karnam, D Brabazon, M Takai, IU Ahad, John Bosco Balaguru Rayappan and Uma Maheswari Krishnan, ACS Chemical Neuroscience, 11 (24), 40244047422020, https://doi.org/10.1021/acschemneuro.0c00355
- Fabrication of a Nano-Interfaced Electrochemical Triglyceride Biosensor and its Potential Application towards Distinguishing Cancer and Normal Cells, M Sasya, K Jayanth Babu, JBB Rayappan, Uma Krishnan, Chemistry Select, 5, 13492-135012
- 2020, https://doi.org/10.1002/slct.202003771
- Emerging vistas on electrochemical detection of diabetic retinopathy biomarkers, KSS Devi, M Sasya, UM Krishnan, TrAC Trends in Analytical Chemistry, 125, 115838152020, https://doi.org/10.1016/j.trac.2020.115838
- Metabolic Syndrome-An emerging constellation of risk factors: electrochemical detection strategies, M Sasya, KSS Devi, JK Babu, JB Balaguru Rayappan, UM Krishnan, Sensors, 20 (1), 103102019, https://doi.org/10.3390/s20010103
- Exploring hesperidin-copper complex as an enzyme mimic for monitoring macrophage activity, S Madhurantakam, S Selvaraj, JBB Rayappan, UM Krishnan, Journal of Solid State Electrochemistry, 22, 1893-189982018, https://doi.org/10.1007/s10008-018-3883-5
- Nanotechnology-based electrochemical detection strategies for hypertension markers, UMK Sasya Madhurantakam, K. Jayanth Babu, John Bosco Balaguru Rayappan, Biosensors and bioelectronics, 116, 67-80322018, https://doi.org/10.1016/j.bios.2018.05.034
- Enzyme-free monitoring of glucose utilization in stimulated macrophages using carbon nanotube-decorated electrochemical sensor, S Madhurantakam, JB Karnam, JBB Rayappan, UM Krishnan, Applied Nanoscience, 7, 773-78062017, https://doi.org/10.1007/s13204-017-0617-4
- Non-enzymatic detection of glucose in fruits using TiO2-Mn3O4 hybrid nano interface, K Jayanth Babu, Madhurantakam Sasya, Noel Nesakumar, Prabakaran Shankar, Manju Bhargavi Gumpu, Bhat Lakshmishri Ramachandra, Arockia Jayalatha Kulandaisamy, John Bosco Balaguru Rayappan, Applied Nanoscience, 7, 309-316112017, https://doi.org/10.1007/s13204-017-0571-1
- Fabrication of mediator-free hybrid nano-interfaced electrochemical biosensor for monitoring cancer cell proliferation, S Madhurantakam, KJ Babu, JBB Rayappan, UM Krishnan, Biosensors and Bioelectronics, 87, 832-841372017, https://doi.org/10.1016/j.bios.2016.09.039
- Nano interfaced biosensor for detection of choline in triple negative breast cancer cells, V Thiagarajan, S Madhurantakam, S Sethuraman, JBB Rayappan, Uma Maheswari Krishnan, Journal of colloid and interface science, 462, 334-34037, https://doi.org/10.1016/j.jcis.2015.10.014
- Electrochemical enzymeless detection of superoxide employing naringin-copper decorated electrodes, S Madhurantakam, S Selvaraj, N Nesakumar, S Sethuraman, JBB Rayappan, Uma Maheswari Krishnan, Biosensors and Bioelectronics, 59, 134-139, https://doi.org/10.1016/j.bios.2014.03.029
Timeline
Research Scientist
The University of Texas at Dallas
09.2023 - Current
Post-Doctoral Research Associate
The University of Texas at Dallas
04.2021 - 08.2023
JSPS Postdoctoral Fellow
Japan Society for the Promotion of
03.2019 - 03.2021
INSPIRE-Senior Research Fellow
Department Of Science And Technology
09.2015 - 09.2018
INSPIRE-Junior Reseacrh Fellow
Department Of Science And Technology
12.2012 - 08.2015
Ph.D. - Electrochemical Biosensors
School of Chemical And Biotechnology
Master of Science - Nanomaterials and Technology
Sri Venkateswara University
M.Sc. - Masters project
Department of Materials Engineering
B.Sc. - Biotechnology
Sri Venkateswara University
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