Sen Han Yang
3420 Finnian Way#134, Dublin,CA
Summary
Detail-oriented Laboratory Manager effective at keeping cell therapy based laboratory operating efficiently. Proficient in managing supplies, analyzers, facilities and problem solving. Committed to spend leisure time to learn advanced scientific and regulation knowledge over next 2 years with John Hopkins University's MS in Biotechnology Program to take on challenging new role in the cell therapy industry.
Overview
12
12
years of professional experience
Work History
Lab Manager
Acepodia Biotech
12.2021 - Current
- Established and reinforced laboratory guidelines to be compliant with regulations such as OSHA, CERS, EPA, and GxP.
- Negotiated vendor contracts for cost-effective procurement of lab equipment and supplies without sacrificing quality.
- Trained and supervised Research associates, fostering environment of collaboration and continuous improvement.
- Managed inventory control for cell sources, reagents and supplies, ensuring timely restocking and proper disposal of hazardous materials.
- Retained part of Research Scientist tasks.
Research Scientist
Acepodia Biotech
03.2018 - 12.2021
- Contributed in 3 successful IND submissions by providing in vitro, in vivo, andquality control data of the products.
- Performed, and validated assays to determine the potency and quality of product.
- Cultured cell lines and primary T cells to meet experimental needs with good laboratory practice and aseptic technique.
- Managed collaborating CRO's in vivo studies by preparing materials and recording clinical observations of NSG/SCID mice, and data analysis.
- Maintained sufficient supplies and monitored the sterility of Laboratory.
- Support collaborating clinical sites by ensuring sufficient supplies and equipment with timely communications.
Medical Laboratory Technician
Evergreen Healthcare
09.2017 - 02.2018
- Operated, troubleshoot, and maintained Roche Cobas 6000 series C and E modules, Beckman Coulter DxH 800 and Iris UA analyzer, Stago Compact Coagulation analyzer, and Siemens PFA analyzer to analyze all specimens and provide data to physicians.
- Enhanced patient-doctor relationship with accurate and timely diagnostic testing for various medical conditions.
Research Assistant Intern
Academia Sinica
07.2012 - 06.2013
- Conducted independent research on PubMed about assigned project regarding structure of proteins.
- Built Database with detailed manual scans on target proteins and performed basic molecular analysis including DNA sequence alignment and structural alignment.
- Interpreted data and prepared presentations to team members during briefings.
- Contributed in writing manuscripts.
Education
Certification Program - Medical Laboratory Technology
Shoreline Community College
Seattle, WA08.2017
Bachelor of Science - Biochemistry And Molecular Biology
University of California - Davis
Davis, CA06.2014
Skills
Cellular Biology : Primary T cell culture and γꝽT cell isolation, adherent and suspension cell line culture, Flow cytometry, Cell proliferation assays and luminescence based Cytotoxicity assay
Molecular Biology : PCR, qPCR, Gel electrophoresis, DNA Extraction, Western blot and ELISA
General Lab skills: Microbiology techniques including streaking, Gram stain, Wright stain, microscopy, Aseptic technique, Data collection and analysis
Analytical software : Microsoft Office suite, GraphPad Prism, Aura Spectral imaging system, Flowjo
Contributed Publications
- Li, H.-K.; Hsiao, C.-W.; Yang, S.-H .; Yang, H.-P.; Wu, T.-S.; Lee, C.-Y.; Lin, Y.-L.; Pan, J.; Cheng, Z.-F.; Lai, Y.-D.; Hsiao, S.-C.; Tang, S.-W. A Novel off-the-Shelf Trastuzumab-Armed NK Cell Therapy (ACE1702) Using Antibody-Cell-Conjugation Technology. Cancers 2021 , 13, 2724. https://doi.org/10.3390/cancers13112724
- Li, Hao-Kang, Ching-Wen Hsiao, Sen-Han Yang , Hsiu-Ping Yang, Tai-Sheng Wu, Zih-Fei Cheng, Chia-Yun Lee, et al. 2020. “772 a Potent and Off-The-Shelf ONK Cell Therapy Product Targets HER2+ Cancer Cells and Resists Suppressive Tumor Microenvironment.” Journal for ImmunoTherapy of Cancer 8 (Suppl 3). https://doi.org/10.1136/jitc-2020-SITC2020.0772.
- Li, Hao-Kang H., Tai-Sheng E. Wu, Ching-Wen S. Hsiao, Sen-Han S. Yang , Chia-Yun S. Lee, Yan-Liang J. Lin, Zih-Fei Z. Cheng, et al. 2020. “Abstract 2169: ACE1702: A Potent and Off-The-Shelf ONK Cell Therapy Product.” Cancer Research 80 (16_Supplement): 2169–69. https://doi.org/10.1158/1538-7445.am2020-2169.
Timeline
Lab Manager
Acepodia Biotech
12.2021 - Current
Research Scientist
Acepodia Biotech
03.2018 - 12.2021
Medical Laboratory Technician
Evergreen Healthcare
09.2017 - 02.2018
Research Assistant Intern
Academia Sinica
07.2012 - 06.2013
Certification Program - Medical Laboratory Technology
Shoreline Community College
Bachelor of Science - Biochemistry And Molecular Biology
University of California - Davis
Similar Profiles
Ameya PaulAmeya Paul
QC Microbiologist at PSC Biotech Ltd, contractor at MSD Dublin BiotechQC Microbiologist at PSC Biotech Ltd, contractor at MSD Dublin Biotech
Felix StemesederFelix Stemeseder
Scientist, Virology at HOOKIPA Biotech GmbHScientist, Virology at HOOKIPA Biotech GmbH
Jinjie LyuJinjie Lyu
Laboratory Assistant Intern at Harbin Essence BiotechLaboratory Assistant Intern at Harbin Essence Biotech