Shalini Chakraborty
LARAMIE,UNITED STATES
Summary
Results-oriented achiever with proven ability to exceed targets and drive success in fast-paced environments. Combines strategic thinking with hands-on experience to deliver impactful solutions and enhance organizational performance.
Overview
7
7
years of professional experience
Work History
Ph.D Candidate
University of Wyoming
09.2019 - Current
- Research Areas: Molecular Biology, Neural stem cell research , cell-cell signaling, cell division
- Research overview: Identification of specific cell type/(s) in brain that are important for the development of Microcephaly by Abnormal spindle (Asp), Determination of the role of Asp as a regulator of Notch signaling. We are addressing these questions using various genetic tools available in the Drosophila community, high resolution confocal microscopy, micro computed tomography as well as high resolution domain specific yeast two-hybrid and protein biochemistry assays.
Masters Student
St. Xavier's College
05.2017 - 07.2019
- Research Area : Microbiology, Plant-microbe interactions
- Research Overview: Formulation of novel biopesticides using compatible microorganism and an accurate CFU count. In this investigation, a unique biopesticide has been designed by using compatible microorganisms based on their parasitic, predatory and biochemical relationships
Summer Intern
National Institute of Pharmaceutical Education and Research (NIPER)
04.2019 - 06.2019
- Research area: Molecular biology
- Research Overview: Examining the roles of two transporter genes namely, L. donovanimiltefosine transporter (LdMT) and its specific beta subunit LdRos3 in incurring
resistance against miltefosine using CRISPR Cas9 system.
Education
Ph.D. - Molecular and Cellular Life Sciences
University of Wyoming
Laramie, WY12-2025
M.Sc. - Microbiology
St. Xavier's College (Autonomous)
07.2019
B.Sc. - Microbiology
University of Calcutta
06.2017
Skills
Gateway and TOPO cloning
Immunofluorescence and microscopy
micro-computed tomography
Image analysis and segmentations using Fiji, Imaris, Dragonfly
Western blotting and IP
Protein interaction analysis using AlphaFold 2 and 3
Nucleofection using S2 cells from Drosophila and cell culture
Tissue and organ dissections from fruitflies
One color flow cytometry
ELISA
Microsoft Office
Presentations
Oral: Cell-type dependent function of abnormal spindle (asp) in brain growth and development, Molecular Monday Seminar, Department of Molecular Biology, University of Wyoming, 2023
Exploring the link between the microcephaly protein Asp and the Notch signaling pathway, Molecular Monday Seminar, Department of Molecular Biology, University of Wyoming, 2022
Identifying novel protein interactors of Abnormal Spindle, a key regulator of proper brain size, Northwest Developmental Meeting, Society for Developmental Biology, 2021
Poster: Assessing cell-type specific roles of abnormal spindle (asp) in brain growth and development, 64th Annual Drosophila Research Conference, Genetics Society of America, 2023
Probing molecular and cellular mechanisms of abnormal spindle (asp) function in brain growth and development, Wyoming INBRE Spring Retreat, 2022
Exploring novel interactions of Abnormal spindle and identification of cell type/(s) important for proper brain growth, 63rd Annual Drosophila Research Conference, Genetics Society of America, 2022,
Identifying novel protein interactors of Abnormal Spindle, a key regulator of proper brain size, Northwest Developmental Meeting, Society for Developmental Biology, 2021,
Efficacy of a unique microbial association in augmentation of plant productivity, 106th Indian Science Congress, India, 2018
Degrees
- Ph.D. in Molecular and Cellular Life Sciences, University of Wyoming, 09/01/19, Ongoing, In Progress
- M.Sc. in Microbiology, St. Xavier's College (Autonomous) University of Calcutta, 05/01/17, 07/01/19, Completed
- B.Sc. in Microbiology, University of Calcutta, 08/01/14, 06/01/17, Completed
Communityoutreach
- Judge, Wyoming State Science Fair, 2022
- Mentor, Mentoring of Molecular and Cellular Life Sciences (MCLS) Rotation Students., 2020-2022
Publications
The neurodevelopmental transcriptome of the Drosophila melanogaster microcephaly gene abnormal spindle reveals a role for temporal transcription factors and the immune system in regulating brain size, in review, Mannino MC, Cassidy MB, Florez S, Rusan Z, Chakraborty S, Schoborg TA, Genetics, 2023, doi.org/10.1101/2023.01.09.523369
Timeline
Ph.D Candidate
University of Wyoming
09.2019 - Current
Summer Intern
National Institute of Pharmaceutical Education and Research (NIPER)
04.2019 - 06.2019
Masters Student
St. Xavier's College
05.2017 - 07.2019
M.Sc. - Microbiology
St. Xavier's College (Autonomous)
B.Sc. - Microbiology
University of Calcutta
Ph.D. - Molecular and Cellular Life Sciences
University of Wyoming
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