Shane Guidaboni
Somerville,MA
Summary
Skilled Molecular Technologist with background in clinical laboratory settings. Experience includes performing complex molecular diagnostic tests, interpreting results, and ensuring accuracy of data. Strengths include deep understanding of molecular biology techniques, high attention to detail, problem-solving skills, and ability to work collaboratively within cross-functional teams. Previous impact includes implementing streamlined processes for increased efficiency and providing essential contributions to research projects.
Overview
10
10
years of professional experience
Work History
Molecular Technologist II
FOUNDATION MEDICINE
Cambridge, MA
02.2023 - 08.2024
- Conducted patient sample testing following strict SOPs, ensuring high standards in genetic analysis, managing throughput of more than 384 biological samples per day
- Prepared and quantified nucleic acids for Next Generation Sequencing (NGS), including digestion, library preparation, extraction/quantification, hybrid capture, and Illumina-based sequencing
- Contributed to process improvements and SOP updates by collaborating cross-functionally with other teams
- Provided training and mentorship to peers, strengthening team capabilities and operational accuracy, and performed routine preventative maintenance on lab equipment
Molecular Technologist I
FOUNDATION MEDICINE
Cambridge, MA
12.2019 - 02.2023
Analyst Lab Coordinator II
SANOFI-GENZYME
Allston, MA
11.2018 - 11.2019
- Streamlined sample management for Quality Control (QC) labs under cGMP standards, enhancing lab throughput
- Oversaw archival of lab records and maintained 100% accuracy in documentation processes
- Managed lab inventory and equipment availability, supporting seamless lab operations and reducing downtime
Lab Support Technician - Microbiology
BOSTON MEDICAL CENTER
Boston, MA
03.2018 - 10.2018
- Verified and processed patient specimens, reducing errors and improving data reliability
- Supervised new technicians, enhancing accuracy in specimen processing and lab protocols, increasing operational efficiency
- Utilized aseptic techniques in preparing and plating microbiological samples, ensuring high standards in sample integrity and contamination control
Lab Support Technician - Central Receiving Lab
BOSTON MEDICAL CENTER
Boston, MA
09.2017 - 03.2018
Quality Control Auditor
Toxikon Corporation
Bedford, MA
11.2016 - 02.2017
- Audited biological and chemical studies to ensure full compliance with GLP standards, maintaining high accuracy in audit findings
- Reviewed GMP/GLP reports, reducing deviations and enhancing lab throughout
Manufacturing Technician
Vericel Corporation
Cambridge, MA
01.2016 - 03.2016
- Maintained mammalian cell cultures under cGMP regulations, adhering closely to SOPs and batch production records, ensuring high standards in cell culture integrity
- Conducted regular monitoring within an ISO 7 cleanroom environment, ensuring media integrity and reducing contamination risk
Research Associate Intern
Monica Colaiacovo Lab - Harvard Medical School
Boston, MA
12.2014 - 01.2016
- Supported genetic research on C.elegans using CRISPR/Cas9, contributing to significant project advancements
- Applied techniques such as gel electrophoresis, and microscopy to assist with high-impact laboratory experiments
- Collaborated with team members by attending weekly lab meetings, leading to an increase in efficiency of assay results
Education
Bachelor's of Science - Biomedical Lab and Clinical Science
BOSTON UNIVERSITY
Boston, MA05-2016
Skills
- Animal handling
- Aseptic technique
- Cell culture techniques
- Microscopy
- Extraction
- Quantification
- PCR proficiency
- DNA/RNA sequencing analysis
- DNA/RNA isolation and purification
- Next generation sequencing
- Spectroscopy
- Gel electrophoresis
- Automation platforms (Hamilton, Biomek, Agilent)
- Molecular biology techniques
- Lab Information Systems (LIMS)
- Molecular diagnostics expertise
Timeline
Molecular Technologist II
FOUNDATION MEDICINE
02.2023 - 08.2024
Molecular Technologist I
FOUNDATION MEDICINE
12.2019 - 02.2023
Analyst Lab Coordinator II
SANOFI-GENZYME
11.2018 - 11.2019
Lab Support Technician - Microbiology
BOSTON MEDICAL CENTER
03.2018 - 10.2018
Lab Support Technician - Central Receiving Lab
BOSTON MEDICAL CENTER
09.2017 - 03.2018
Quality Control Auditor
Toxikon Corporation
11.2016 - 02.2017
Manufacturing Technician
Vericel Corporation
01.2016 - 03.2016
Research Associate Intern
Monica Colaiacovo Lab - Harvard Medical School
12.2014 - 01.2016
Bachelor's of Science - Biomedical Lab and Clinical Science
BOSTON UNIVERSITY
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