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Siomara Hernández-Rivera
Study Manager - Research Associate II
Ann Arbor,MI
Summary
Dedicated to using excellent research, investigation and project management abilities to optimize management, organization and reporting of clinical data. Results-driven, precise and systematic with quick learning and collaborative nature. Organized and dependable candidate successful at managing multiple priorities with a positive attitude. Willingness to take on added responsibilities to meet team goals.
Overview
1
1
Language
11
11
years of post-secondary education
10
10
years of professional experience
Work History
Study Manager
Labcorp Drug Development
Ann Arbor, MI
04.2020 - Current
- Study manager of more than 20 high-quality client base preclinical oncology studies.
- Overseeing interdisciplinary preclinical research programs with Good Clinical Practices, relevant Standard Operating Procedures, and regulatory requirements.
- Acts as primary liaison between company and costumer to ensure project launch, conduct, and closeout according to customer’s and company’s contractual agreement.
- Lead preclinical team to ensure quality, timelines, budget management.
- Accountable for all projects deliverables for assigned projects.
- Continually keep educating myself on market issues/trends, product knowledge, and new therapeutics.
- Coordinates activities and deliverables of all project conduct partners and proactively identifies and manages issues.
- Actively evaluate and identifies, recruit, investigate, external expert identification and external collaboration management with other departments.
- Accountable for maintenance of project information on variety of databases and systems.
- Maintains and evaluates project progress by maintaining timelines and other tracking/analysis tools.
- Provides oversight for development and implementation of project plans in compliance with controlled documents.
- Independently prepares, coordinate, and presents project material at internal and external meetings.
- Directs activities of assigned Project Support staff; line manages and mentor other project management team members and clinical staff; facilitates team building and communication.
- Prepares reports for clients and management.
- Implements resource strategies to achieve project goals.
- Develops contingency planning and risk mitigation strategies to ensure successful delivery of project goals.
- Trained and support new study managers and team members.
- Facilitates training in accordance with protocol and project requirements, including therapeutics, protocol specific, and process training.
- Communicates data effectively in group meetings and client study updates and reports.
- Able to coordinate, collaborate, data summary, strong analytical, and complete project according to specification in set deadline.
- Small animal handling and manipulation/restraint to include procedures not limited to in vivo: dosing, measuring, weighing, and surgeries; ex vivo: necropsy and sampling, extensive understanding of clinical signs.
- Understand multiple disease models and related pharmacology, biology, procedures and data generation.
- Help with drafting of SOPs, VUFs, and other documents.
- Perform drug preparation.
- Knowledge of underlying calculations and ability to follow clients' specifications.
- Utmost attention and awareness of humane animal care practices and initiatives to be applied in daily work.
- In-depth knowledge of Animal Care and Use principles and applications.
- Certification to work in laboratory is BioSafety Level II.
- Leadership role as Co-lead in ASCEND.
- Gathered, arranged and corrected research data to create representative graphs and charts highlighting results for presentations.
- Validated incoming data to check information accuracy and integrity while independently locating and correcting concerns.
- Streamlined research processes to meet tight deadlines for multiple projects.
- Collaborated with leadership team to identify relevant questions and determine best methods of collection.
- Distilled large amounts of information and produced reports, spreadsheets and documents outlining key details
Research associate
Michigan State University, MSU
East Lansing, MI
10.2016 - 03.2020
- Project Manager of high quality neuroscience and physiology Department of Defense project.
- Responsible for designing, monitor, planning, analyzing, and reviewing for completion of experiment using Gulf War Illness mouse model.
- Expertise of mouse handling and manipulation/restraint in procedures of in vivo: dosing, measuring, weighing, and surgeries; ex vivo: necropsy and sampling.
- Assist in implementation of bench-scale assays onto understanding Gulf War Illness and mechanisms that affects gastrointestinal tract using ELISA, immunohistochemistry as many others.
- Perform drug preparation and record results and report findings.
- Responsible of writing and submitting successful protocol to Institutional Animal Care and Use Committee for use of Gulf War Illness and endometriosis mouse model.
- Communicates data effectively in monthly group meetings, oral and poster presentation that have gaining me several awards in local and national scientific meetings.
- Provide education to health care worker, professional, and general community about different gastroenterology and neuroscience diseases.
- Able to coordinate, collaborate, data summary, strong analytical, and complete project according to specification in set deadline that has end up in successful first author publications with use of outsides sources such as scientific literature.
- Gathered, arranged and corrected research data to create representative graphs and charts highlighting results for presentations.
- Validated incoming data to check information accuracy and integrity while independently locating and correcting concerns.
- Streamlined research processes to meet tight deadlines for multiple projects.
- Collaborated with leadership team to identify relevant questions and determine best methods of collection.
- Distilled large amounts of information and produced reports, spreadsheets and documents outlining key details.
- Experienced research physiologist and pharmacologist with demonstrated success in disseminating scientific results evidenced by 20+ award-winning presentations, 3 awarded fellowships, and 10+ publications in peer review journals.
Research assistant
Ponce Health Sciences University
Ponce, PR
01.2011 - 06.2016
- Experience with designing experiments, established troubleshooting procedures, plans, execute, and analyzed research that helps understand effects of stress on nociception in animal model of endometriosis.
- Collaborates in different research projects such as HIV-1 protein Nef mouse model induces changes in gastrointestinal tract of rats and how probiotic mixture alters morphology and secretion profile of human macrophages.
- Expertise of Rat handling and manipulation/restraint in procedures of in vivo: dosing, measuring, weighing, and surgeries; ex vivo: necropsy and sampling.
- Responsible of writing and submitting successful protocol to Institutional Animal Care and Use Committee for use of endometriosis rat model.
- Implement and validate real-time PCR for in-vitro understanding of endometriosis diseases.
- Use laboratory techniques such as western blots and ELISA in mammalian cell culture.
- Responsible for archive, revise, maintain and expand cell lines utilizing aseptic technique.
- Provide education to health care worker, professional, and general community about women health, and gastroenterology and neuroscience diseases.
- As vice-president of Graduate Student Association in Biomedical Science and part of curriculum committee I participate in design and review meetings with faculty, administrators and student to performed community outreach, planned fundraising opportunities, identified opportunities, offers solutions, participates in developing improvement of Ph.D.
- Biomedical science curriculum.
- Able to summarize, analyze, proficient with statistical experiments analysis, and convey data information that has end up in six successful first and secondary author publications with use of outsides sources such as scientific literature.
- Gathered, arranged and corrected research data to create representative graphs and charts highlighting results for presentations.
- Planned, modified and executed research techniques, procedures and tests.
- Developed macros, special formulas and other actions to produce reliable and consistent statistical reviews.
- Worked both independently and collaboratively in fast-paced laboratory environment.
- Prepared materials for reports, presentations and submission to peer-reviewed journal publications.
- Attended seminars and symposiums to improve overall knowledge and understanding.
- Demonstrated strong writing skills to generate original correspondence and reports.
- Performed statistical, qualitative and quantitative analysis.
Education
Ph.D. - Biomedical Sciences
Ponce Health Sciences University
Ponce, PR 07.2010 - 06.2016
Bachelor of Science - Biology
University of Puerto Rico - Mayaguez
Mayaguez, PR 06.2005 - 06.2010
Skills
SOP compliance
undefinedAccomplishments
- Rodent handling, intraperitoneal and subcutaneous injection, tail vein injection and blood collection, vaginal cytological smear collection, oral gavage, behavioral protocol, nociceptive tests, perfusion, and fixation
- Rodent stereotaxic brain surgeries and endometriosis model
- Mouse colonic ex vivo calcium imaging from the myenteric plexus, Organ bath colonic motility, and permeability (Ussing chamber)
- Fluorescence immunohistochemistry and imaging techniques
- DNA, RNA, and protein extraction and purification
- Molecular cloning techniques: Real-time PCR
- Western blot
- Enteric glia RNA Seq
- Multiplex assay using Luminex
- ELISA assay
- Fluorescence In-situ hybridization
- MACS cell separation
- Mammalian cell culture
Software
GraphPad prism
Imagine J
Origins
Photoshop
Labware
Timeline
Study Manager
Labcorp Drug Development
04.2020 - Current
Research associate
Michigan State University, MSU
10.2016 - 03.2020
Research assistant
Ponce Health Sciences University
01.2011 - 06.2016
Ph.D. - Biomedical Sciences
Ponce Health Sciences University
07.2010 - 06.2016
Bachelor of Science - Biology
University of Puerto Rico - Mayaguez
06.2005 - 06.2010
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