Summary
Overview
Work History
Education
Skills
Accomplishments
Fellowships and Awards
Publications
Skills
Timeline
Generic

Sahar Jafari, Ph.D.

Silver Spring,MD

Summary

Accomplished senior materials scientist with a track record of leadership and innovation in developing leading edge technologies and materials across industries including biomaterials, magnetic alloys, ceramics and pharmaceuticals. My projects have led to patents in the areas of materials science xxxx I enjoy collaborating with cross-functional teams, and respond especially well to fast-paced and goal-oriented environments.

Overview

15
15
years of professional experience

Work History

Senior Scientist- Materials Scientist

Refeyn
08.2023 - 12.2023
  • Rapidly attained subject matter expertise in applying Refeyn's innovative technology for measuring the size and mass of nano materials in less than 90 days of joining the team. Conducted advanced materials characterization techniques, employing multiple methods to comprehensively understand the physical properties of nano materials. Integrated data from various instruments and provided a comprehensive analysis of material behavior and properties. As a result, successfully transitioned the project from its early phases to the development stage.
  • Led cross-functional teams by strategically determining benchmarking analytics, crafting comprehensive test plans, and designing impactful experiments. Orchestrated end-to-end development of an innovative nano materials analytical product with collaboration with internal hardware, software, and marketing teams, as well as external collaborators.
  • Conducted a comprehensive application market analysis, made a strategic roadmap for the product development. Presented findings to the senior management team, utilizing insights to formulate project timelines and details. The thorough market analysis and trend research directly contributed to the precise positioning of the innovative product within the materials analytical industry.
  • Utilized JIRA to streamline and enhance project managemnt, ensuring effective collaboration, transparent communication, and efficient workflow tracking. Leveraged JIRA's features to improve task prioritization, project planning, and overall team productivity in the product development context.
  • Bobz said: monthly CEO updates (Directed the project as the lead, overseeing its comprehensive execution and orchestrating key milestones. Effectively delivered project progress updates to the senior management (CEO) in a high-level monthly base.

Senior Scientist- Materials Scientist & Engineer

Weinberg Medical Physics
04.2016 - 07.2023
  • Designed and developed innovative materials (magnetic materials, Lipid nanoparticles, Liposomes) as a lead materials scientist, steering research initiatives, and leveraging expertise in material design, synthesis, and characterization. Advanced cutting-edge materials science through creative solutions, contributed to breakthroughs in diverse applications.
  • Designed and implemented innovative processes (customized additive manufacturing, laser assisted materials synthesis, laser assisted materials production process in millimeter and centimeter scales) for the synthesis of complex materials, showcasing a proactive approach to material science. Applied creative problem-solving skills to develop novel methodologies, contributing to advancements in materials technology and improving overall production process efficiency.
  • Conducted thorough characterization of synthesized novel materials, employing advanced analytical techniques to assess their structural, mechanical, and functional properties. Contributed valuable insights to the understanding of material microstructure-properties behavior, facilitating informed decisions in further optimizing and tailoring materials for specific applications.
  • Obtained funding by successfully applying for government grants, translating experimental results into compelling proposals and financial opportunities. Proactively identified relevant grant opportunities, designed experiments and tests to create innovative materials and applications, aligning with the goals of the funding programs.
  • Demonstrated exceptional leadership skills by enhancing the company's materials science research internship program. Specifically tailored the program to support aspiring young scientists from local universities, providing training and mentorship for their continued education and professional development.

Senior Scientist-Materials & Process Engineer

On Demand Pharmaceuticals
04.2022 - 10.2022
  • Utilized advanced materials analytical techniques, such as spectroscopy, chromatography, and microscopy, to analyze the physical and chemical properties of drug product formulations during development and manufacturing.
  • Leveraged materials science technical expertise to lead the synthesizing the small molecule injectable drug products, activities leading teams from R&D through tech transfer. Applied an advanced skill set, encompassing statistical analysis, Design of Experiments (DOE), risk management, and manufacturing process analysis to manufacture the drug products in small scales and successfully 95% scale up.
  • Directed a team of scientists and junior scientists, successfully navigating drug development phases from initial planning through GMP tech transfer, ensuring adherence to phase gate requirements and obtaining approvals at critical milestones.
  • Authored comprehensive technical test plans, technical reports, risk assessments, and SOPs supporting materials manufacturing efforts and experimental procedures.

Department Chair and Assistant Prof.

Ahvaz Azad University
09.2012 - 03.2015
  • Led staff of twenty tenured and adjunct professors, approved, and directed annual departmental budget, developed department staffing plans, recruited and approved new hires, instructed ceramics and materials science engineering courses at undergraduate and graduate levels.
  • Developed new merit-based criteria for assessing performance for both faculty and students.
  • Developed new courses curricula and new research programs for the department.

Junior Researcher

National Institute For Materials Science
05.2009 - 03.2012
  • Innovatively formulated and engineered novel alloys for Toyota hybrid cars, conducted comprehensive characterization of microstructural, structural, and physical properties of developed alloys, performing continuous analysis of the structure-property-magnetic properties relationship and successfully identified key factors influencing alloy performance.
  • Meticulously evaluated various advanced manufacturing metallurgical processes in 1 and 10 Kg batches, strategically selecting the optimal technique that yielded the desired physical and microstructural properties in accordance with Toyota's specifications.
  • SME at operating the state-of-the-art characterization devices including HRTEM, Cross Beam SEM, FIB, and Atom Probe.
  • Led a joint project with Vacuumschmelze GmbH & Co., Germany, and Dr. Herzer's team, characterizing microstructural properties of nanocrystalline Fe-Cu-Si-B-P alloys and modifying the alloy composition for the enhanced magnetic induction.

Education

Ph.D. - Materials Science & Engineering

Iran University of Science & Technology
Tehran, Iran
2014

Master of Science - Materials Science & Engineering-Ceramics

Iran University of Science & Technology
Tehran, Iran
2006

Bachelor of Science - Materials Science & Engineering-Ceramics

International University of Imam
Qazvin, Iran
2003

Skills

  • Materials Science and Engineering
  • Materials Characterization
  • Research and Development
  • Multi-departmental teams
  • Written and verbal communication
  • Assay Development
  • Materials synthesis and processes
  • Scale up and manufacturing
  • Project Management

Accomplishments

  • Designed and formulated novel magnetic alloys that improved the efficiency of Toyota hybrid propulsion systems.
  • Developed manufacturing processes for Toyota by analyzing microstructure-physical properties of magnetic materials, contributing to advancements in automotive propulsion technology.
  • … patents submitted as first inventor on creative techniques to synthesize magnetic materials with complex structure and materials with novel magnetic properties.
  • Formulated novel liposomal materials for targeted drug delivery for US army.
  • Led the design of manufacturing of two sterile injectable drug products at a pharmaceutical setting in small scale and 95% scale up, integrating principles of materials characterization, statistical analysis, and materials manufacturing. The successful application of these methodologies resulted in the filing of 2 FDA ANDAs.
  • Led multi departmental team in a successful redevelopment of a product with improvement in nano materials characterization performance of the product

Fellowships and Awards


  • Graduate Assistantship, Iran University of Science and Technology, Tehran, Iran, 2003-2005, 2007-2014
  • National Institute for Materials Science, internship at Research Center for Magnetic and Spintronic Materials “, Japan, 2009
  • Toyota scholarship, Tsukuba, Japan, 2009-2012

Publications

Selected Peer-Reviewed Journal Articles:

· Sahar Jafari, et al, “Opening the Blood Brain Barrier with an Electropermanent Magnet System”, Pharmaceutics · Jul 20, 2022.

· Lamar O. Mair; Olivia Hale; Sahar Jafari; et al ” Magnetic Microdevices for MRI-Based Detection of SARS-CoV-2 Viruses” IEEE Open Journal of Engineering in Medicine and Biology, Vol1, 2020.

· Sahar Jafari, et al, “Magnetic drilling enhances intra-nasal transport of particles into rodent brain”, Journal of Magnetism and Magnetic Materials, Vol 469, Pages 302-305, 2019.

· Irving N. Weinberg, Lamar O. Mair, Sahar Jafari, et al., “Platform for Image-Guided Non-Invasive Brain Delivery of Magnetic Particles. Concept Design and Technical Progress”, IEEE MAGNETICS LETTERS, Vol 9, 1503805, 2018.

· Lamar O Mair, Luz J Martinez-Miranda, Lynn K Kurihara, Aleksandar Nacev, Ryan Hilaman, Sagar Chowdhury, S. Jafari, et al., “Electric-field responsive contrast agent based on liquid crystals and magnetic nanoparticles, AIP ADVANCES 8, 056731, 2018.

· S. Jafari, et al , “Magnetically Targeted Delivery through Cartilage, AIP ADVANCES 8, 056717, 2018.

· Lamar O. Mair, Aleksandar Nacev, Ryan Hilaman, Pavel Y. Stepanov, Sagar Chowdhury, S. Jafari, Jeffrey Hausfeld, Amy J. Karlsson, Mark E. Shirtliff, Benjamin Shapiro, Irving N. Weinberg, " Biofilm Disruption with Rotating Microrods Enhances antimicrobial Efficacy," Journal of Magnetism and Magnetic Materials, Volume 427, Pages 81–84, 2017.

· L. O. Mair, B. A. Evans, A. Nacev, P. Y. Stepanov, R. Hilaman, S. Chowdhury, S. Jafari, et al., "Magnetic microkayaks: propulsion of microrods precessing near a surface by kilohertz frequency, rotating magnetic fields," Nanoscale, 9, 3375-338, 2017.

· S. Jafari, et al, "Atom Probe Analysis and Magnetic Properties of Nanocrystalline Fe84.3Si4B8P3Cu0.7 ," Journal of Alloys and Compounds, Volume: 674, Pages: 136-144, 2016.

· S. Jafari, et al , "Three-Dimensional Atom Probe Analysis and Magnetic Properties of Fe85Cu1Si2B8P4Melt Spun Ribbons," Journal of Magnetism and Magnetic Materials, Vol. 401, pp. 1123-1129, 2016.

· S. Mollazadeh, Siamak Ajalli, Tahereh S.Jafarzadeh Kashi, Bijan Eftekhai Yekta, Jafar Javadpour, S. Jafari, Abbas Youssefi, Akbar Fazel, "The Effect of Aqueous Media on the Mechanical Properties of Fluorapatite-Mullite Glass-Ceramics," Journal of Dental Materials, Volume 31, Issue 11, Pages 1370–1376, 2015.

· S. Jafari, et al, "The Effect of Phosphorous on Microstructure and Magnetic Properties of Fe-based Alloys," Journal of Metallurgical and Materials Engineering, vol.26, No.1, 2015.

· S. Jafari, et al, "Microstructural and Magnetic Properties Study of Fe-P Rolled Sheet Alloys," Journal of Magnetism and Magnetic Materials, Vols. 358-359, pp. 38-43, 2014.

Book Chapters:

· Irving N. Weinberg, Lamar O. Mair, S. Jafari, et al, Image-guided Placement of Magnetic Neuroparticles as a Potential High- Resolution Brain-Machine Interface, In: Evolving BCI Therapy engaging brain state dynamics, IntechOpen, CRS Press, 2018.

· Lamar O. Mair, Aleksandar N. Nacev, Sagar Chowdhury, Pavel Stepanov, Ryan Hilaman, S. Jafari, Benjamin Shapiro and Irving N. Weinberg, Magnetic Particle Transport in Complex Media, In: Clinical Applications of Magnetic Nanoparticles, Taylor and Francis group, CRS Press, 2017.

Skills

Laboratory equipment, Laboratory tests, Regulatory compliance, Manufacturing process, Materials, JMP, new product development, Scanning electron microscopy, Transmission electron microscopy, Optical microscopy, Focused ion beam, Atom probe, X-ray diffraction (XRD), ceramics processing, alloys processing, JIRA, statistical analysis, Chromatography- HPLC, UV-VIS, FTIR, Raman spectroscopy-TG-DSC, Magnetic measurements (VSM, SQUID)

Timeline

Senior Scientist- Materials Scientist

Refeyn
08.2023 - 12.2023

Senior Scientist-Materials & Process Engineer

On Demand Pharmaceuticals
04.2022 - 10.2022

Senior Scientist- Materials Scientist & Engineer

Weinberg Medical Physics
04.2016 - 07.2023

Department Chair and Assistant Prof.

Ahvaz Azad University
09.2012 - 03.2015

Junior Researcher

National Institute For Materials Science
05.2009 - 03.2012

Ph.D. - Materials Science & Engineering

Iran University of Science & Technology

Master of Science - Materials Science & Engineering-Ceramics

Iran University of Science & Technology

Bachelor of Science - Materials Science & Engineering-Ceramics

International University of Imam
Sahar Jafari, Ph.D.