Summary
Overview
Work History
Education
Skills
Accomplishments
Software
Quote
Timeline
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Sophia Ruppe

Sophia Ruppe

Computational Bioengineering
Lakewood,CA

Summary

Fascinated by the potential of developing mathematical models of complex biochemical systems for achieving unprecedented breakthroughs in medicine and biotechnology. Built a complete cell free kinetic model of fatty acid synthesis in E.coli to discover the optimal strategies for modifying the pathway as a means of fuel production. Fit and validated the model using both literature data and data from in lab experimental collaborations. Succeeded in predictive modeling for multiple strategies now published in literature for maximizing and tailoring fatty acid chain production. Seeking to use these skills in data analysis and mathematical modeling to contribute to team efforts in cutting edge biological engineering.

Overview

8
8
years of professional experience
12
12
years of post-secondary education

Work History

Business Intelligence Analyst

La Clinica
07.2022 - Current
  • Researched and presented medical operations models to business leaders.
  • Partnered with AMA to implement their research program for reducing physician burnout by 2-3% per year.
  • Impact analysis reports for novel clinical and operations programs.
  • Collaborated in design of clinic leaderboard detailing KPIs.

Graduate Research Assistant - Biological Eng.

CU Boulder - Fox Lab
01.2016 - 12.2020
  • Constructed mathematical models in Matlab of cellular pathway of Escherichia coli fatty acid synthesis through leveraging of literature data.
  • Collaborated with colleagues to reconstitute the fatty acid pathway in a cell free environment.
  • Used data from our cell-free platform to improve our model and optimize pathway production.
  • Contributed to three scientific papers for publication based on modelling results.
  • Expressed and purified proteins, performed enzyme activity assays and other statistical and quantitative analyses used in protein engineering.

Graduate Teaching Assistant

CU Boulder
01.2016 - 12.2017
  • Planned and delivered lectures and course materials to simplify convoluted topics in thermodynamics for students.
  • Mentored students through careful listening and testing of their understanding in office hours and one-on-one communication.
  • Maintained excellent organization in managing student assignments, proctoring tests and providing grades.

Education

Ph.D. - Chemical And Biological Engineering

University of Colorado Boulder
Boulder, CO
08.2015 - 12.2020

Master of Science - Chemical And Biological Engineering

University of Colorado Boulder
Boulder, CO
08.2015 - 05.2018

Bachelor of Science - Chemical And Biological Engineering

University of Southern California
Los Angeles, CA
08.2011 - 06.2015

Skills

Analysis of data using mathematical models, statistics and visualizationundefined

Accomplishments

  • Earned recognition in peer-reviewed publications in ACS Catalysis and PNAS.
  • USC Provost's Undergraduate Research Fellowship
  • CU Boulder ChBE Doctoral Fellowship
  • Outstanding Presenter Award (Biophysics Supergroup)
  • NIH Molecular Biophysics Training Grant Award

Software

MATLAB

Python

Quote

The opposite of a true statement is a false statement, but the opposite of a profound truth may well be another profound truth.
Niels Bohr

Timeline

Business Intelligence Analyst

La Clinica
07.2022 - Current

Graduate Research Assistant - Biological Eng.

CU Boulder - Fox Lab
01.2016 - 12.2020

Graduate Teaching Assistant

CU Boulder
01.2016 - 12.2017

Ph.D. - Chemical And Biological Engineering

University of Colorado Boulder
08.2015 - 12.2020

Master of Science - Chemical And Biological Engineering

University of Colorado Boulder
08.2015 - 05.2018

Bachelor of Science - Chemical And Biological Engineering

University of Southern California
08.2011 - 06.2015

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Sophia RuppeComputational Bioengineering