SOWMYA CHAKRAVARTHULA

• Understand and comply with GLP requirements and follow Methods, Plans and SOP/SWPs and related lab procedures; comply with safety policies, comply with company policies
• Use properly maintain lab instrument and equipment appropriately for assigned tasks
• Conduct Bio-analysis validation and sample analysis with minimal supervision meeting company quality standards for more than 5 studies.
• Conduct method development under supervision
• Prepare worksheets for study
• Data processing and table preparation (i.e tests which have tested for drug discovery)
• QC data and preparation, data integration, raw data integration, raw data printing, preparation of chromatograms for report, use of LC-MS/MS, use of Watson LIMS, etc.)
• Maintain accurate record of work and study documentation per Good Documentation Practices as per company Standard Operating Procedures.
• Conduct Planned maintenance and Operational qualification (PM/OQ) and calibration of Mass spectrometers as planned or needed
• Maintain clean and safe lab work environment
• Maintain proprietary and confidential information
• Assumes other activities and responsibilities as assigned.

• Collect samples from billing area and build in loads and process them using Hamilton Micro lab star testing systems approximately 5000 samples per day.
• Running processed samples on LCMS/MS system to find out required drug percentages and quantities from patient samples
• Analyzing data using Analyst and processing lab reports
• Troubleshoot instruments as needed
• Had very thorough knowledge on Lab based SOPs and had firm base understanding on them
• Training people as required
• Able to handle multiple Drug testing with little supervision
• Performs daily and weekly maintenance of LCMS systems
• Conduct Good laboratory procedures while making reagents and processing samples
• Able to handle produce patient samples results on timely manner even while working with heavy and stressful environments
• Maintain clean lab environment at all times.
• Followed safety protocols to maintain safe and secure laboratory environment.
• Assisted in training of new staff members, ensuring proper knowledge transfer and adherence to safety protocols.
• Prepared reagents and solutions, making readily available during testing for convenience.
• Prepared laboratory samples for analysis and performed data entry for accurate reporting.

Receive, Label and analyze samples (Blood, Covid, Urine)

• Design and execute laboratory testing according standard procedures, make observations and interpret findings
• Organize and store all chemicals substances, fluids and compressed gases according to safety instructions
• Conduct experiments under defined conditions to verify/reject various types of hypothesis using refined scientific methods
• Record all data and results in specified forms (paper and electronic) with accuracy and responsibility
• Maintain equipment and assist in ordering laboratory supplies
• Ensure that all safety guidelines are followed strictly at all times and maintain clean and orderly environment
• Experience in operating electrical and non-electrical laboratory equipment and potentially dangerous substances (flammable liquids, infectious bacteria, biohazards etc.)
• Involved in analyzing Covid RNA Auto extraction and purification using ANDiS 350 Automated Nucleic Acids Extraction System
• Have knowledge about Thrombosis scientific Automated RNA extraction system and also RT-PCR analysis of Covid samples.
• Documented information by maintaining daily logs and equipment record books.
• Collected and performed analytical testing on in-process product.

• Involved in Prenatal diagnosis of genetic disorders approximately 200 samples per day.
• Perform Amniotic chromosomal analysis (karyotyping) & Human karyotyping
• Involved in identification of chromosomal structural abnormalities like deletions & additions of chromosomes in patient samples
• Involved in dropping and staining of amniotic samples
• Involved in preparing and maintaining Stock & working media for amniotic cells
• Involved in maintaining lab conditions sterile and aseptic
• Review and maintain patient summary register.
• Established culture of continuous learning and professional development within technology team, enhancing overall skills and capabilities.
• Evaluated finished assemblies for compliance with standard procedures and design requirements.
• Reduced downtime for critical systems through proactive maintenance and timely troubleshooting.
• Coordinated inventory supplies and equipment to maximize team productivity.