Tejashri Jadhav
Somerville,USA
Summary
With a focus on leveraging in vitro functional cytotoxicity assays using CAR-/TCR-T cells to advance immuno-oncology therapy, I've honed skills in immunological techniques, directly contributing towards the pursuit of innovative immunotherapies. I'm committed to the meticulous science in the industry that can lead to breakthroughs in treating life-altering diseases.
Overview
4
4
years of professional experience
1
1
Certification
Work History
Research Associate, Cancer Immunology
BioNTech US
07.2023 - Current
- Responsible for evaluating functional potential of TCR-T cell enhancers in vitro to be developed as therapy for solid tumors.
- As part of a multi-disciplinary team, I work closely with other Cell Therapy teams at USA and Germany BioNTech sites
Teaching Assistant-Immunology/Protein Biochemistry
University of Illinois Chicago, College of Medicine
07.2022 - 05.2023
- Organized laboratory sessions and trained students to perform immunological techniques, such as ELISA, collection and processing of bone marrow cell/femur tissue samples from mice as well as protein assays and protein purification.
- Checked assignments, proctored tests and provided grades according to university standards.
- Provided timely and constructive feedback on assignments, enabling students to refine their work and achieve higher grades.
- Supported instructors in grading exams and papers, maintaining accurate records of student performance throughout the semester.
- Mentored students through office hours and one-on-one communication.
Mentor: Summer Science and Summer Medical Research Training (SMaRT) Programs
University of Illinois Chicago, College of Medicine
06.2022 - 05.2023
- Trained a high school intern in conducting an 8-week research project titled, 'Functional Characterization of Monoclonal Antibodies Generated Against a Vaccine Candidate for Lymphatic Filariasis' at UIC College of Medicine, Rockford.
Editor, Life Sciences
CACTUS Communications Pvt. Ltd.
06.2020 - 07.2021
- Edited over 450 manuscripts written by non-native authors to ensure that the final text is in standard scientific English and free of unclear or unidiomatic sentences
- Adhered to job-specific instructions and formatted manuscripts according to the scientific journal specified by clients
- Undertook a project on Alt-text writing for high school biology textbook
Reviewer, Life Sciences
CACTUS Communications Pvt. Ltd.
06.2020 - 07.2021
- Reviewed edited manuscripts critically prior to submission to clients.
Education
Master’s - Medical Biotechnology
University of Illinois Chicago, College of Medicine
Rockford, IL05.2023
Bachelor of Technology - Genetic Engineering
SRM Institute of Science & Technology
Chennai, India05.2019
Skills
- Mammalian/ Human/ Tumor cell culture
- In vitro 2D and 3D cytotoxicity assays
- Retroviral transduction
- Magnetic activated cell sorting (MACS)
- Multicolor flow cytometry
- Cytokine detection assays: Meso Scale Discovery (MSD), ELISA
- Antibody labeling
- Fluorescence microscopy
- Recombinant protein expression and purification
- Western blot
- Animal handling
- Molecular techniques: RNA/DNA isolation, First-strand cDNA synthesis, PCR/Real-time PCR
- Scientific Writing
- Software: RTCA, FlowJo, GraphPad Prism, Electronic Laboratory Notebook (ELN), Microsoft Office
Volunteer Experience
Bunker Hill Community College (BHCC), 09/2024 to Present
Cambridge, MA, USA
- Mentor a student pursuing an Associate's Degree in Biotechnology over building their industry resume and cover letter and preparing them for mock interviews.
CASPAR Shelters, 08/2023
Cambridge, MA, USA
- Helped organize meals for the homeless at a shelter for a day alongside other BioNTech US colleagues.
Teach For India (TFI), 07/2019 to 12/2019,
Mumbai, MH, India
- Taught Mathematics and English to select Grade 4 students requiring personal attention at a public school.
CRY- Child Rights & You, 12/2018 to 01/2019
Mumbai, MH, India
- Worked in an online fundraising campaign to support children to get back to school.
Research Projects
Therapeutic Potential of Monoclonal Antibodies Generated Against rBmHAXT for Lymphatic Filarial Infection, 01/2022 to 03/2023
University of Illinois Chicago, College of Medicine, Rockford, IL, USA, Mentor: Dr. Ramaswamy Kalyanasundaram, Professor and Head of the Department of Biomedical Sciences
- Identified the best monoclonal antibody (mAb)-producing clone for quality assurance in the cGMP manufacturing of recombinant BmHAXT protein vaccine.
- Determined therapeutic potential of mAbs in vitro in an antibody-dependent cell-mediated cytotoxicity assay using Brugia malayi infective larvae and in vivo in a murine model of lymphatic filariasis.
Endocrine Disruptor Induced Gene Expression Changes in the HPG Axis of Zebrafish, 01/2019 to 05/2019
SRM Institute of Science & Technology, Chennai, TN, India, Mentor: Dr. S. Kirankumar, Associate Professor and Head, Department of Genetic Engineering
- Studied gene expression changes in zebrafish hypothalamic–pituitary–gonadal (HPG) axis due to exposure to the herbicide atrazine.
- Treated juvenile zebrafish were found to have altered levels of target reproductive genes.
Certification
- HMX Pro Immunology—Immuno-oncology online certification course, Harvard Medical School, MA (11/2023)
- HMX Pro Pharmacology—Clinical Drug Development online certification course, Harvard Medical School, MA (Present)
- HMX Pro Genetics—Cancer Genomics and Precision Oncology online certification course, Harvard Medical School, MA (Present)
Awards
- Academic Excellence Award, MS Medical Biotechnology Program, University of Illinois College of Medicine (12/2023)
- Client's Favorite Contractual Editor for the Quarter July–September 2020, CACTUS Communications, Pvt. Ltd. (10/2020)
Timeline
Research Associate, Cancer Immunology
BioNTech US
07.2023 - Current
Teaching Assistant-Immunology/Protein Biochemistry
University of Illinois Chicago, College of Medicine
07.2022 - 05.2023
Mentor: Summer Science and Summer Medical Research Training (SMaRT) Programs
University of Illinois Chicago, College of Medicine
06.2022 - 05.2023
Editor, Life Sciences
CACTUS Communications Pvt. Ltd.
06.2020 - 07.2021
Reviewer, Life Sciences
CACTUS Communications Pvt. Ltd.
06.2020 - 07.2021
Master’s - Medical Biotechnology
University of Illinois Chicago, College of Medicine
Bachelor of Technology - Genetic Engineering
SRM Institute of Science & Technology
Similar Profiles
S.Pelin Temeloglu ArslanS.Pelin Temeloglu Arslan
Research Associate at BioNTech SEResearch Associate at BioNTech SE
Christy ParkerChristy Parker
Associate Director, Clinical Operations at BioNTechAssociate Director, Clinical Operations at BioNTech
Senayit GebrekidanSenayit Gebrekidan
Quality Control Manager, Incoming Goods at Biontech SEQuality Control Manager, Incoming Goods at Biontech SE
Sofia YerardiSofia Yerardi
Volunteer at Sweet Paws RescueVolunteer at Sweet Paws Rescue
Briana C. ValenteBriana C. Valente
Material Controller at Oticon MedicalMaterial Controller at Oticon Medical