Summary
Overview
Work History
Education
Skills
Affiliations
Accomplishments
References
Timeline
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Thomas Houser

Fulshear,TX

Summary

Talented and proven problem solver with a focus on making customers lives easier, from internal customers developing novel scientific instrumentation, to external customers using that instrumentation to conduct scientific research.

Overview

Work History

Software Developer / Bioinformatician

Bio-Rad Laboratories, Inc
Hercules , CA
1998 - Current
  • I develop and maintain algorithms, calculations, and software for use with instrumentation for DNA sequencing, qPCR (Quantitative PCR) and dPCR (Digital PCR) technologies, for the study of DNA.
  • A partial list of algorithms and calculations I have developed and been responsible for: Gel electrophoresis lane finding, gel electrophoresis base calling, qPCR sigmoid curve baselining, qPCR Cq detection, matrix algebra based color deconvolution, qPCR melt curve clustering (patented), dPCR poisson quantification and confidence intervals, ddPCR (droplet digital PCR) signal processing algorithms for four different instruments, a clustering algorithm for a COVID detection assay, a clustering algorithm for COVID detection in wastewater, droplet volume calibration and detection.
  • I have also developed software and interactive visualizations for all of the above, as both customer facing software and internal R&D tools.

Education

Bachelor of Arts - Computer Science

University of Wisconsin - Madison
Madison, WI
1998-05

Skills

  • qPCR (Quantitative PCR) calculations and algorithms
  • dPCR (Digital PCR) calculations and algorithms
  • ddPCR (Droplet Digital PCR) calculations and algorithms
  • Clustering algorithms
  • Signal Processing algorithms (signal conditioning, baselining, peak finding, measurements)
  • Interactive software tools for customer and internal R&D uses

Affiliations

  • Classical pianist
  • Grower of fig trees

Accomplishments

  • US patent 8606527, SNP Detection by Melt Curve Clustering

References

References available upon request.

Timeline

Software Developer / Bioinformatician

Bio-Rad Laboratories, Inc
1998 - Current

Bachelor of Arts - Computer Science

University of Wisconsin - Madison
Thomas Houser