Tyler Buss
Kalamazoo
Summary
Detail-oriented and results-driven scientist with 6 years of experience in ligand binding assay development and validation. Proven expertise in planning, executing, and managing scientific projects, with a strong focus on assay development to meet client needs and adhere to guidance proposed by regulatory agencies (FDA/EMA/USDA/EPA). Highly skilled in ELISA techniques for biomarker analysis, immunodiagnostics and pharmacokinetics, and quality control. Adept at cross-functional collaboration, data analysis, and technical reporting to support regulatory and research-based objectives. Committed to driving innovation and maintaining high standards in laboratory practices.
Overview
7
7
years of professional experience
Work History
Project Scientist - Research Scientist I
Charles River Laboratories
02.2025 - Current
- Administered oversight for method development and method validation of ligand binding assays.
- Evaluated the logistics of multiple discovery-level preclinical large molecule drug development projects.
- Aided clients with fit-for-purpose Enzyme-Linked Immunosorbent Assay (ELISA) development, validation, and sample analysis in GLP and nGLP settings.
- Adhered to and maintained compliance with criteria from regulatory bodies for method validation and sample analysis to support Innovative New Drug (IND) submissions.
- Analyzed, interpreted, and reported biological data for pharmacokinetics and immunogenicity using tools such as Watson LIMS, SoftMax Pro, and Excel.
Project Scientist - Senior Associate Scientist
Charles River Laboratories
02.2024 - 02.2025
Project Scientist - Associate Scientist
Charles River Laboratories
02.2023 - 02.2024
Research Analyst III
Charles River Laboratories
07.2022 - 02.2023
- Conducted ELISA method development assessments, validation assessments, and sample analysis for multiple large projects.
- Demonstrated assay developmental insight and technical expertise with laboratory equipment.
- Developed internal methodologies for efficient mass tissue homogenization.
- Traveled to Montreal to learn hybridization ELISA processes at another CRL site.
- Implemented hybridization ELISA at Mattawan site via training presentation and walkthrough guide.
- Performed peer data review and quality control of datasets, plate maps, and inventory management systems.
Research Analyst II
Charles River Laboratories
01.2022 - 07.2022
Research Specialist
Charles River Laboratories
06.2021 - 01.2022
Laboratory Technologist
Forensic Fluids Laboratories
03.2019 - 05.2021
- Performed and validated serum and oral-based covid testing.
- Performed competitive ELISA testing on oral fluid in a high throughput lab to detect pharmaceuticals and illicit drugs in a CLIA certified lab.
- Analyzed and reviewed ELISA screening data, and indicated samples for confirmatory analysis.
- Validated PCP and opiate ELISA kits for Drugs of Abuse (DoA) and therapeutic markets.
- Extracted analytes of interest from meconium samples using solid-phase extraction plates for LCMS-MS analysis.
- Trained new colleagues in specimen processing and screening methodologies.
- Compiled regulatory documents and SOPs.
- Liaison between Indiana and Michigan labs.
- 95% timely quarter project completion rate
- Software: LIMS, BioTek Gen5, MassLynx, SharePoint, Microsoft Office
Product Specialist
Ray Skillman Dealership
07.2018 - 03.2019
- Assisted guests with technical vehicle questions for Ford and Hyundai models.
- Facilitated smooth transitions from landing guests on the vehicle they want, to purchasing a vehicle.
- Ensured monthly sales metrics were met after onboarding was completed.
Education
Bachelor of Science - Biology, Chemistry Minor
Indiana University
Bloomington01.2018
Skills
- Project Management
- Client Interfacing
- High-Throughput Laboratory
- ELISA Methodologies
- PK and ADA Assays
- Data Analysis
- Laboratory techniques
- Tissue Homogenization
- Troubleshooting
- Communication
- Good Laboratory Practices (GLPs)
- Organizational skills
Timeline
Project Scientist - Research Scientist I
Charles River Laboratories
02.2025 - Current
Project Scientist - Senior Associate Scientist
Charles River Laboratories
02.2024 - 02.2025
Project Scientist - Associate Scientist
Charles River Laboratories
02.2023 - 02.2024
Research Analyst III
Charles River Laboratories
07.2022 - 02.2023
Research Analyst II
Charles River Laboratories
01.2022 - 07.2022
Research Specialist
Charles River Laboratories
06.2021 - 01.2022
Laboratory Technologist
Forensic Fluids Laboratories
03.2019 - 05.2021
Product Specialist
Ray Skillman Dealership
07.2018 - 03.2019
Bachelor of Science - Biology, Chemistry Minor
Indiana University
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