Uchechukwu Udensi
Conroe,TX
Summary
Research professional specializing in spectral domain optical coherence tomography (SD-OCT) and statistical analysis. Enhanced data integrity and streamlined workflows while delivering training and consultancy. Collaborated with teams to drive successful research outcomes through innovative imaging techniques.
Overview
21
21
years of professional experience
1
1
Certification
Work History
Research Assistant. II (Integrative Physiology)
Baylor College of Medicine
05.2016 - Current
- Conducting spectral domain ophthalmic imaging employing Spectral Domain Optical Coherence Tomography (SD-OCT) to acquire and analyze depth-resolved ocular tissue microstructure, and to identify retinal and corneal abnormalities such as ulcerated cornea and retinal vessel tortuosity, resulting in improved patient assessments.
- Utilizing InVivoVue Diver Analysis software to manually mark and analyze ocular images obtained with the Spectral Domain Ophthalmic Imaging System (SDOIS).
- Assisted over three scientists and senior researchers with data collection and analysis across imaging modalities, facilitating successful research outcomes, including (see publications bbelow).
- Consulted and trained external Principal Investigators and Researchers on effective utilization of Imaging Core equipment, leading to improvements in their project outcomes.
- Conducted statistical analysis of research data using Excel to support research findings, uncovering significant insights.
- Developed comprehensive spreadsheet to streamline workflow and enhance data abstraction procedures in Excel and Access.
- Collaborate with Imaging Core Director to ensure operational effectiveness and efficiency.
- Contributed to NIH-funded projects to support ongoing research efforts.
- Possesses comprehensive knowledge of the principles and applications of OCT.
Lead Animal Care Technician (Center for Comparative Medicine)
Baylor College of Medicine
10.2015 - 04.2016
- Maintained pathogen-free environment, ensuring animal wellbeing and supporting research integrity.
- Monitored micro and macro environmental conditions in animal holding rooms to support animal health.
- Maintained animal housing system to ensure optimal care and welfare.
- Managed equipment inventory and supplies, guaranteeing availability for seamless operations.
- Ensured proper and accurate documentation of all necessary forms, facilitating compliance and traceability.
Research Associate (Pre-Clinical)
Ophthalmic Research Associates Inc.
03.2014 - 07.2015
- Conducted animal pharmacology studies using ophthalmoscope to investigate ocular melanoma, allergy, and dry eye, enhancing understanding of ophthalmic diseases.
- Assisted with OCT imaging and analysis using R-Class OCT system to acquire high-resolution 3D images of retina and cornea fundus, improving research quality in small and large animals.
- Collected, maintained, and analyzed scientific data to support specialized research efforts using GraphPad Prism, ensuring data integrity and reliability.
- Assisted Project Manager in developing and documenting protocols, facilitating adherence to research standards and regulatory compliance.
- Exhibited independence in resolving methodological challenges during research.
- Contributed to creation of technical reports, summaries, protocols, and quantitative analyses, ensuring clarity and compliance in research documentation.
- Harvested ocular tissues from mice, rats, and rabbits, and managed the shipping of samples.
Research Assistant (Immunology)
Lexicon Pharmaceuticals Inc.
09.2013 - 01.2014
- Performed Experimental Autoimmune Encephalomyelitis assays to investigate disease mechanisms.
- Conducted various immunological studies: Ova and Serum ELISA Analysis, Collagen-Induced Arthritis protocol.
- Facilitated tissue collection from mice to improve data quality for immunological research.
- Investigated biomarker drug studies to evaluate therapeutic efficacy.
- Executed animal dosing processes, including intradermal and intravenous, ensuring protocol adherence.
- Executed various immunization and dosing schemes in F1 mice.
Advanced Senior Technician (Vivarium)
Lexicon Pharmaceuticals Inc.
10.2005 - 09.2013
- Conducted inbred breeding and collected breeding data while managing quarantine operations to enhance animal husbandry practices.
- Maintained pathogen-free environment in animal holding rooms, ensuring optimal animal health and supporting research integrity.
- Monitored environmental conditions in animal holding rooms to ensure optimal habitat.
- Coordinated equipment inventory and supplies with Supervisor, ensuring continuous availability for vivarium operations.
- Ensuring proper and accurate documentation of all necessary forms.
- Prepared and updated various Standard Operating Procedures.
Ophthalmology (Intern)
Lexicon Pharmaceuticals Inc.
12.2010 - 02.2011
- Administered ophthalmic drugs via subcutaneous, intraperitoneal, and topical methods to optimize treatment efficacy.
- Conducted mouse intraocular pressure (IOP) measurement using the TonoLab Technique and fundus imaging with an ophthalmoscope.
- Assisted in various ophthalmology assay studies, such as experimental autoimmune uveitis (EAU), dry eye protocols, and light-induced degeneration assays.
- Executed dissection and harvesting of mouse eyes and retinas, facilitating critical research initiatives.
- Utilized Aperio ScanScope Scanner and Spectrum Software to scan and analyze inner and outer nuclear layers of eyes, enhancing data accuracy for research.
Education
MSc. - Physics (Radiation and Health Physics)
University of Ibadan
Ibadan, Nigeria08-1995
B. Tech - Meteorology
Federal University of Technology
Akure, Nigeria08-1992
Skills
- InVivoVue Imaging for OCT
- InVivoVue Diver
- Statistical Analysis
- Data analysis
- Microsoft Access
- Microsoft Office
- TeamViewer
Certification
Certified Laboratory Animal Technologist, American Association of Laboratory Animal Science, 2009
Awards And Publications
- Identification of novel genes required for eye development by high-throughput screening of mouse knockouts, Nature Communications, 12/18, 03/19
- Rapid and Integrative Discovery of Retina Regulatory Molecules, Cell Reports, 08/18
- Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes, BMC Genomics, 01/25
- Ocular Phenotyping of knockout mice identifies genes associated with late adult retinal phenotypes, Investigative Ophthalmology & Visual Science, 06/25
Technical Skills
InVivoVue Imaging for OCT, InVivoVue Diver, Microsoft Access, Peachtree Accounting, TeamViewer, Microsoft Office
Lab Techniques
- Optical Coherence Tomography Imaging
- Animal Dissection
- Administration of doses to animals
- Immunostaining
- Protocol and assay documentation
- Animal preparation for imaging
- Techniques for reagent formulation
- Microscopic techniques
- Biological and immunoassay testing
Timeline
Research Assistant. II (Integrative Physiology)
Baylor College of Medicine
05.2016 - Current
Lead Animal Care Technician (Center for Comparative Medicine)
Baylor College of Medicine
10.2015 - 04.2016
Research Associate (Pre-Clinical)
Ophthalmic Research Associates Inc.
03.2014 - 07.2015
Research Assistant (Immunology)
Lexicon Pharmaceuticals Inc.
09.2013 - 01.2014
Ophthalmology (Intern)
Lexicon Pharmaceuticals Inc.
12.2010 - 02.2011
Advanced Senior Technician (Vivarium)
Lexicon Pharmaceuticals Inc.
10.2005 - 09.2013
MSc. - Physics (Radiation and Health Physics)
University of Ibadan
B. Tech - Meteorology
Federal University of Technology