Udana Ariyaratne
Detroit,MI
Summary
Dedicated Biochemist and Cell Biologist experienced in research, data analysis, and optimizing testing protocols. Demonstrates innovative problem-solving abilities and a strong vision for success.
Overview
10
10
years of professional experience
Work History
Postdoctoral Researcher
Wayne State University School of Medicine
Detroit, MI
02.2024 - Current
- Designing and executing the experiments to detect gene expression changes in embryonic development after the effect of household pesticide propoxur using Zebrafish as a model organism.
- Investigated impact of various perfluorinated substances on development of acute lymphoblastic leukemia in zebrafish
Graduate Research Assistant
Wayne State University
Detroit, MI
08.2018 - 12.2023
- Identified non-histone substrates of HDAC6 catalytic domain 1 with trapping mutants
- Worked with mammalian cell lines HEK293, MCF7, and MDA-MB-231 for different cell biological aspects, including the maintenance of cell lines, transfection of DNA using mammalian expression plasmids, and adeno viral transduction to overexpress protein of interest, and siRNA transfection for knocking down of protein of interest.
- Protein separation by SDS-PAGE and identification by immunoblotting and immunofluorescence. Prepared the samples for liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. Analyzes the proteomics data using bioinformatics software such as MaxQuant, GeneMANIA, Cytoscape, and DAVID GO analysis in the process of HDAC substrate identification.
Graduate Research Assistant
Sam Houston University
Huntsville, TX
08.2014 - 07.2016
- Synthesized Acyl Homoserine Lactones (AHLs) and thiolactones (AHLTLs) analogs and characterized the products using nuclear magnetic resonance (NMR), liquid chromatography-mass spectrometry (LC-MS).
- Purified recombinant cytochrome P450BM3 enzyme from the bacterial system and performed enzyme kinetic studies of P450BM3 on AHLs and AHLTs using an enzyme-coupled assay in UV-Vis spectrometry.
Education
Ph.D. - Biochemistry
Wayne State University
Detroit, MI04-2024
Master of Science - Chemistry
Sam Houston State University
Huntsville, TX08-2016
Bachelor of Science - Biological Sciences
University of Kelaniya
Sri Lanka03-2008
Skills
- Research Methodology Design
- Systematic Work Plan Development
- Research Documentation
- Creative Problem Solving
- Instructional Experience
- Data Analysis
- Assay development
- Constructive Peer Reviews
- Professional Mentoring
Timeline
Postdoctoral Researcher
Wayne State University School of Medicine
02.2024 - Current
Graduate Research Assistant
Wayne State University
08.2018 - 12.2023
Graduate Research Assistant
Sam Houston University
08.2014 - 07.2016
Ph.D. - Biochemistry
Wayne State University
Master of Science - Chemistry
Sam Houston State University
Bachelor of Science - Biological Sciences
University of Kelaniya
Similar Profiles
REYA AHMEDREYA AHMED
Biomedical Career Advancement Program at Wayne State University School of MedicineBiomedical Career Advancement Program at Wayne State University School of Medicine
Brent Smith, M.D.Brent Smith, M.D.
Senior Diversity Equity Inclusion Officer at Wayne State University School Of MedicineSenior Diversity Equity Inclusion Officer at Wayne State University School Of Medicine
Dianne NelsonDianne Nelson
Ryan White Program Social Worker at Wayne State University School Of MedicineRyan White Program Social Worker at Wayne State University School Of Medicine