Summary
Overview
Work History
Education
Skills
Websites
Timeline
Generic

Udana Ariyaratne

Detroit,MI

Summary

Dedicated Biochemist and Cell Biologist experienced in research, data analysis, and optimizing testing protocols. Demonstrates innovative problem-solving abilities and a strong vision for success.

Overview

10
10
years of professional experience

Work History

Postdoctoral Researcher

Wayne State University School of Medicine
Detroit , MI
02.2024 - Current
  • Designing and executing the experiments to detect gene expression changes in embryonic development after the effect of household pesticide propoxur using Zebrafish as a model organism.
  • Investigated impact of various perfluorinated substances on development of acute lymphoblastic leukemia in zebrafish

Graduate Research Assistant

Wayne State University
Detroit , MI
08.2018 - 12.2023
  • Identified non-histone substrates of HDAC6 catalytic domain 1 with trapping mutants
  • Worked with mammalian cell lines HEK293, MCF7, and MDA-MB-231 for different cell biological aspects, including the maintenance of cell lines, transfection of DNA using mammalian expression plasmids, and adeno viral transduction to overexpress protein of interest, and siRNA transfection for knocking down of protein of interest.
  • Protein separation by SDS-PAGE and identification by immunoblotting and immunofluorescence. Prepared the samples for liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. Analyzes the proteomics data using bioinformatics software such as MaxQuant, GeneMANIA, Cytoscape, and DAVID GO analysis in the process of HDAC substrate identification.

Graduate Research Assistant

Sam Houston University
Huntsville , TX
08.2014 - 07.2016
  • Synthesized Acyl Homoserine Lactones (AHLs) and thiolactones (AHLTLs) analogs and characterized the products using nuclear magnetic resonance (NMR), liquid chromatography-mass spectrometry (LC-MS).
  • Purified recombinant cytochrome P450BM3 enzyme from the bacterial system and performed enzyme kinetic studies of P450BM3 on AHLs and AHLTs using an enzyme-coupled assay in UV-Vis spectrometry.

Education

Ph.D. - Biochemistry

Wayne State University
Detroit, MI
04-2024

Master of Science - Chemistry

Sam Houston State University
Huntsville, TX
08-2016

Bachelor of Science - Biological Sciences

University of Kelaniya
Sri Lanka
03-2008

Skills

  • Research Methodology Design
  • Systematic Work Plan Development
  • Research Documentation
  • Creative Problem Solving
  • Instructional Experience
  • Data Analysis
  • Assay development
  • Constructive Peer Reviews
  • Professional Mentoring

Timeline

Postdoctoral Researcher

Wayne State University School of Medicine
02.2024 - Current

Graduate Research Assistant

Wayne State University
08.2018 - 12.2023

Graduate Research Assistant

Sam Houston University
08.2014 - 07.2016

Ph.D. - Biochemistry

Wayne State University

Master of Science - Chemistry

Sam Houston State University

Bachelor of Science - Biological Sciences

University of Kelaniya

Similar Profiles

  • REYA AHMED

    REYA AHMEDREYA AHMED

    Biomedical Career Advancement Program at Wayne State University School of MedicineBiomedical Career Advancement Program at Wayne State University School of Medicine

    View Profile
  • Brent Smith, M.D.

    Brent Smith, M.D.Brent Smith, M.D.

    Senior Diversity Equity Inclusion Officer at Wayne State University School Of MedicineSenior Diversity Equity Inclusion Officer at Wayne State University School Of Medicine

    View Profile
  • Dianne Nelson

    Dianne NelsonDianne Nelson

    Ryan White Program Social Worker at Wayne State University School Of MedicineRyan White Program Social Worker at Wayne State University School Of Medicine

    View Profile
Udana Ariyaratne