Summary
Work History
Education
Skills
Languages
Awards
Publications
Timeline
Generic

Valeria Sgambati

Waltham,MA

Summary

Innovative Lead Scientist with 8 years of experience in molecular and cellular biology, bioprocess development, and drug discovery. Skilled in designing novel assays, optimizing workflows, and translating scientific insights into actionable solutions. Known for strong cross-functional collaboration and delivering tailored scientific and technical support to ensure client success.

Work History

Lead Scientific Support

Marathon LS
2024 - 2025
  • Partnered with biopharma teams to design strategies for upstream/downstream bioprocessing, raw-material specs, and custom assay integration, improving workflow efficiency.
  • Standardized key consumables across cell culture, filtration, and analytical workflows, boosting consistency, and lowering costs.
  • Delivered data-driven solutions for cell therapy and biologics programs through close collaboration with R&D, QC, and manufacturing.
  • Trained clients on reagent optimization and assay troubleshooting, strengthening both technical outcomes and customer relationships.
  • Self-motivated, with a strong sense of personal responsibility.
  • Worked effectively in fast-paced environments.

Senior Scientist

Exo Therapeutics
2022 - 2023
  • Built core lab protocols and optimized equipment setups, restoring operational efficiency in a resource-limited biotech environment.
  • Coordinated drug discovery workflows with CRO partners to maintain project momentum.
  • Led experimental design for novel therapeutic candidates, enhancing research methodologies and outcomes.
  • Mentored junior scientists on laboratory best practices and data analysis techniques, fostering team development.

Scientist II | Scientist I

Frequency Therapeutics
2021 - 2022
  • Created a novel assay for screening compounds that regenerate inner-ear progenitor stem cells, earning a promotion to Scientist II within seven months.
  • Led and developed junior researchers, aligning team execution with discovery goals.
  • Contributed to a collaborative, high-performance research culture.
  • Analyzed data using statistical software to identify trends and outcomes.

Education

Ph.D. - Biochemistry

University of Naples Federico II
Italy

M.Sc. - Biology

University of Naples Federico II
Italy

Skills

  • Molecular biology techniques -Expert
  • Cellular biology expertise -Expert
  • Chromatography techniques (HPLC/FPLC) -Expert
  • Patient-derived 3D culture expertise -Expert
  • Organ dissection and injection proficiency -Expert
  • Problem solving -Expert
  • Proficient in Python, R, and SQL for data analysis -Intermediate
  • Proficient in Salesforce, NetSuite, and HubSpot -Advanced

Languages

English
Full Professional
Spanish
Professional Working
Italian
Native or Bilingual

Awards

  • MSK Society Scholars Prize, Prizes and Awards for Postdocs, 2020
  • Marie-Josee’ Kravis Women in Science Endeavor (WISE), Prizes and Awards for Postdocs, 2020

Publications

  • Progressive plasticity during colorectal cancer metastasis, Sgambati V., et al., Nature Communications, 2024
  • Integrated clinical and genomic analysis of dysplasia and carcinoma, Sgambati V., et al., Nature Communications, 2023
  • Carrier protein design for recombinant toxic peptides, Pane K, Sgambati V., et al., PLoS One, 2016

Timeline

M.Sc. - Biology

University of Naples Federico II

Lead Scientific Support

Marathon LS
2024 - 2025

Senior Scientist

Exo Therapeutics
2022 - 2023

Scientist II | Scientist I

Frequency Therapeutics
2021 - 2022

Ph.D. - Biochemistry

University of Naples Federico II

Similar Profiles

CREATE PROFILE
Valeria Sgambati