Vibha Chauhan

Scientific Thought Leader with expertise in leading diverse teams and making impactful contributions to biology, protein engineering, expression, and cell line development. Proven track record in project team leadership, target identification, molecular biology, and protein expression. Functional Senior Director driving proven results within Biotechs. Manages complex occupational issues while meeting business objectives. Strong operational skills and solid experience regulating policies and managing budget expenditures. Collaborates with management teams and stakeholders to uphold company vision.

• Cytokine Conjugates (WO/2021/262985)
• Process for the preparation of non-toxic anthrax vaccine (7888490)
• High-level constitutive production of anthrax protective antigen (7329513)

• Senior Director/Group Head - Protein Engineering, Sanofi, 04/2023, Present, Led cross-functional teams and made strategic decisions on therapeutic programs, Conducted target identification, molecular biology design, and project activities, Established a robust mammalian expression platform and led purification teams, Contributed to pre-clinical study designs, PK studies, and IND filings
• Director - Protein Engineering, Sanofi/Amunix, 10/2018, 03/2023, Led teams and made strategic decisions on therapeutic programs, Conducted target identification, molecular biology design, and project activities, Established a robust mammalian expression platform and led purification teams, Contributed to pre-clinical study designs, PK studies, and IND filings
• Antibody Engineer and Research Cell Line Development Manager, Bristol-Myers Squibb, 12/2009, 09/2018, Managed antibody expression pipelines and cell line development, Optimized CLD workflows and established NGS and computational immunology platforms, Developed transient transfection processes and CRISPR-based gene editing
• Scientist, Research, Antibody Engineering and Molecular Biology, Kalobios Inc., 10/2007, 11/2009, Humanized antibodies using proprietary molecular biology techniques, Established CHO-based antigen expression vectors and cell culture laboratory
• Scientist II, Process Development, Molecular Biology and Cell Culture Development, Genitope Corp., 06/2006, 09/2007, Improved chimeric antibody expression in mammalian cells, Enhanced problematic Mab expression and established a common platform process

• Koong, A.C., Chauhan, V., & Romero-Ramirez, L. (2006). Targeting XBP-1 as a Novel Anti-Cancer Strategy. Cancer Biology & Therapy.
• Feldman, D.E., Chauhan, V., & Koong, A.C. (2005). The Unfolded Protein Response: A Novel Component of the Hypoxic Stress Response in Tumors. Molecular Cancer Research.