Yang Jo Chung
Rockville,MD
Summary
I have been working for 20 years as an experimental hematologist in leukemia section, Genetics Branch, NCI/NIH. My main research was hematopoietic malignancy, especially myelodysplastic syndromes (MDS). Most cases I worked with myeloid malignancy mouse model.
My specialties are hematopoietic stem cell transplantation (HSCT) and flow cytometry analysis. For flow cytometry analysis, I am an early adopter of spectral flow cytometry technique (Northern light, Cytek).
I have very good knowledge and understanding in immunology, leukemia biology, and hematopoietic stem cell biology as well.
Overview
20
20
years of professional experience
Work History
Staff Scientist
National Institutes of Health, NIH
37 Convent Dr Bethesda
09.2012 - Current
- Led interdisciplinary research projects to advance understanding of complex biological systems.
- Developed and optimized experimental protocols to enhance reproducibility and efficiency in laboratory workflows.
- Mentored junior scientists on advanced methodologies and best practices in data analysis and interpretation.
- Collaborated with cross-functional teams to integrate novel technologies into ongoing research initiatives.
- Published findings in peer-reviewed journals, contributing to the scientific community's knowledge base and credibility.
- Presented research outcomes at national conferences, enhancing institutional visibility and fostering collaboration opportunities.
- Analyzed experimental data using statistical software, ensuring accuracy and reliability of results for publication.
Research Fellow
National Institutes of Health
Bethesda, MD
09.2010 - 08.2012
- Led research initiatives in biomedical science, advancing project objectives and timelines.
- Mentored junior researchers, fostering skill development and enhancing team collaboration.
- Developed experimental protocols, ensuring compliance with regulatory standards and best practices.
- Analyzed complex data sets using advanced statistical software to inform research outcomes.
- Presented findings at national conferences, effectively communicating results to diverse audiences.
- Published study details in professional journals to disseminate findings.
Visiting Fellow
National Institutes of Health
Bethesda, MD
09.2005 - 08.2010
- Led research initiatives to advance scientific knowledge in biomedical fields.
- Developed and implemented protocols for data collection and analysis.
- Collaborated with multidisciplinary teams to enhance project outcomes.
- Mentored junior researchers on best practices and methodologies.
- Presented findings at national conferences, fostering knowledge exchange among peers.
- Authored professional scientific papers for publishing in peer-reviewed journals.
Education
Ph.D. - Stem Cell Biology
The Catholic University of Korea
Seoul, Korea08-2002
Master of Science - Microbiology
MyongJi University
Yong-in Korea08-1998
Skills
- Critical thinking capacity
- Lab safety protocols
- Team leadership qualities
- Strong analytical skills
- molecular (DNA, RNA) biology including sub-cloning and general DNA or RNA handling techniques
- mouse work including IV, IP, IM, and SC injection; BM aspiration; tail bleeding; HSCT in congenic model or xenograft model (I am a certified user of 137Cs source irradiator by NIH radiation safety)
- Cell biology including tissue culture, cell cycle analysis, cell purification using FACS or magnetic column (MACS)
- Protein work by FACS staining or Western blot and antibody rebelling
- Hybridoma set up for monoclonal antibody production
- Small molecule (Natural product) isolation using HPLC or FPLC
- Mouse work including IV, IP, IM, and SC injection; BM aspiration; tail bleeding; HSCT in congenic model or xenograft model (I am a certified user of 137Cs source irradiator by NIH radiation safety)
- Cell biology including tissue culture, cell cycle analysis, cell purification using FACS or magnetic column (MACS)
- Protein work by FACS staining or Western blot and antibody rebelling
- Hybridoma set up for monoclonal antibody production
- Small molecule (Natural product) isolation using HPLC or FPLC
Accomplishments
Honors & Scientific Recognition:
1. Individual CASH AWARD, April. 20. 2025
2. Individual CASH AWARD, April. 09. 2024
3. Individual CASH AWARD, May. 23. 2023
4. Individual CASH AWARD, April. 27. 2022
5. Special Joint CASH AWARD, June. 9. 2021
6. Individual CASH AWARD, May. 24. 2021
7. Individual CASH AWARD, April. 12. 2020
8. Individual CASH AWARD, April. 29. 2019
9. Individual CASH AWARD, April. 02. 2018
10. Individual CASH AWARD, April. 18. 2017
11. Individual CASH AWARD, April. 19. 2016
12. Individual CASH AWARD, April. 21. 2015
13. Individual CASH AWARD, April. 16. 2014
14. Individual CASH AWARD, April. 10. 2012
15. Junior Investigator Award, 8th International Workshop on Myeloid Stem Cell Development and
Leukemia, May 10-13, 2009, Annapolis, MD
16. Nov. 7. 2008. Exceptional pay increase, Center for Cancer Research (CCR), NCI
17. Sept. 5. 2007. Poster Award (Travel award), Federation of American Societies for Experimental Biology (FASEB) held on July 21 -26, 2007 in Saxtons River, Vermont
Recent Publications:
1. Matsukawa T, Yin M, Baslan T, Chung YJ, Cao D, Bertoli R, Zhu YJ, Walker RL, Freeland A, Knudsen E, Lowe SW, Meltzer PS, Aplan PD. Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context. The FASEB Journal, 36 (9): e22430, 2022
2. *Bertoli RM, *Chung YJ, Difilippantonio MJ, Wokasch A, Marasco MRB, Klimaszewski H, Garber S, Zhu Y, Walker R, Cao D, Khanna A, Walter MJ, Doroshow JH, Meltzer PS, and Aplan PD. The DNA methyltransferase inhibitor 5-aza-4'-thio-2'-deoxycytidine induces C>G transversions and acute lymphoid leukemia development. Cancer Res, 84 (15):2518-2532, 2024 (*Co-First Author)
3. Bertoli RM, Cao D, Tuckey O, Gammell S, Wokasch A, Chung YJ, Foulks J, and Aplan PD. 5-Azacytidine and Decitabine induce C>G transversions in both murine and human cells. Leukemia, doi: 10.1038/s41375-025-02670-y, 2025
4. Chung YJ, Bertoli RM, Cao D, Walker R, Zhu YJ, Meltzer PS and Aplan PD. Disruption of normal stem cell function and transmission of myelodysplastic syndrome by self-renewal of committed myeloid lineage cells. Stem Cell Reports, (20):102571, 2025
Timeline
Staff Scientist
National Institutes of Health, NIH
09.2012 - Current
Research Fellow
National Institutes of Health
09.2010 - 08.2012
Visiting Fellow
National Institutes of Health
09.2005 - 08.2010
Ph.D. - Stem Cell Biology
The Catholic University of Korea
Master of Science - Microbiology
MyongJi University