Yanira Osorio
Los Angeles,CA
Summary
- Experienced Research Associate with a strong foundation in laboratory techniques and data analysis.
Known for effective communication and training capabilities, facilitating collaboration between researchers and partners. Prepared to leverage expertise to enhance project outcomes and drive scientific advancements. Detail-oriented professional skilled in laboratory techniques, data collection, and effective communication. Proven ability to train staff and manage day-to-day operations efficiently. Hardworking and competent professional with extensive knowledge in clinical laboratory operations. Punctual and professional, willing to work various shifts and driven to perform successfully in solitary role or as part of team.
Detail-oriented professional with a strong background in laboratory research and data collection. Skilled in training staff and fostering collaboration, contributing to enhanced project outcomes and effective team dynamics.
Overview
7
7
years of professional experience
Work History
Research Associate II
Cedars Medical Center
Los Angeles, California
03.2001 - 06.2008
- Performed a variety of laboratory tests on samples including PCR, ELISA, DNA sequencing, cell culture, western blotting, qPCR assays and flow cytometry.
- Examined experiment results to identify underlying causes of scientific findings, contributing to data interpretation and research conclusions.
- Trained new staff on data collection methods and laboratory procedures to ensure accurate data acquisition.
- Trained junior staff members on proper laboratory techniques and procedures.
- Facilitated communication between researchers and external partners to enhance collaboration and project outcomes.
- Participated in weekly team meetings to discuss project progress and challenges.
- Supervised supplies in inventory and notified supervisor of low stock levels.
- Kept lab space and equipment clean to prevent contamination with hazardous substances.
Education
Medicine
Universidad Autonoma De Guadalajara
Jalisco, Mexico06-2018
Skills
- Laboratory techniques
- Data collection and analysis
- Statistical analysis
- Attention to detail
- Time management
- Adaptability
- Team collaboration
- Effective communication
Languages
Spanish
Professional
Accomplishments
1: Osorio Y, Ghiasi H. Recombinant herpes simplex virus type 1 (HSV-1)
codelivering interleukin-12p35 as a molecular adjuvant enhances the protective
immune response against ocular HSV-1 challenge. J Virol. 2005
Mar;79(6):3297-308. doi: 10.1128/JVI.79.6.3297-3308.2005. PMID: 15731224; PMCID:
PMC1075685.
2: Mott KR, Osorio Y, Brown DJ, Morishige N, Wahlert A, Jester JV, Ghiasi H. The
corneas of naive mice contain both CD4+ and CD8+ T cells. Mol Vis. 2007 Sep
28;13:1802-12. PMID: 17960132.
3: Osorio Y, Mott KR, Jabbar AM, Moreno A, Foster TP, Kousoulas KG, Ghiasi H.
Epitope mapping of HSV-1 glycoprotein K (gK) reveals a T cell epitope located
within the signal domain of gK. Virus Res. 2007 Sep;128(1-2):71-80. doi:
10.1016/j.virusres.2007.04.007. Epub 2007 May 11. PMID: 17499382; PMCID:
PMC2020453.
4: Osorio Y, La Point SF, Nusinowitz S, Hofman FM, Ghiasi H. CD8+-dependent CNS
demyelination following ocular infection of mice with a recombinant HSV-1
expressing murine IL-2. Exp Neurol. 2005 May;193(1):1-18. doi:
10.1016/j.expneurol.2004.12.004. PMID: 15817260.
5: Mott KR, Perng GC, Osorio Y, Kousoulas KG, Ghiasi H. A recombinant herpes
simplex virus type 1 expressing two additional copies of gK is more pathogenic
than wild-type virus in two different strains of mice. J Virol. 2007
Dec;81(23):12962-72. doi: 10.1128/JVI.01442-07. Epub 2007 Sep 26. PMID:
17898051; PMCID: PMC2169076.
6: Ghiasi H, Osorio Y, Perng GC, Nesburn AB, Wechsler SL. Overexpression of
interleukin-2 by a recombinant herpes simplex virus type 1 attenuates
pathogenicity and enhances antiviral immunity. J Virol. 2002 Sep;76(18):9069-78.
doi: 10.1128/jvi.76.18.9069-9078.2002. PMID: 12186890; PMCID: PMC136420.
7: Mott KR, Osorio Y, Maguen E, Nesburn AB, Wittek AE, Cai S, Chattopadhyay S,
Ghiasi H. Role of anti-glycoproteins D (anti-gD) and K (anti-gK) IgGs in
pathology of herpes stromal keratitis in humans. Invest Ophthalmol Vis Sci. 2007
May;48(5):2185-93. doi: 10.1167/iovs.06-1276. PMID: 17460278.
8: Osorio Y, Cai S, Hofman FM, Brown DJ, Ghiasi H. Involvement of CD8+ T-cells
in exacerbation of corneal scarring in mice. Curr Eye Res. 2004 Aug-
Sep;29(2-3):145-51. doi: 10.1080/02713680490504632. PMID: 15512961.
9: Ghiasi H, Osorio Y, Hedvat Y, Perng GC, Nesburn AB, Wechsler SL. Infection of
BALB/c mice with a herpes simplex virus type 1 recombinant virus expressing IFN-
gamma driven by the LAT promoter. Virology. 2002 Oct 10;302(1):144-54. doi:
10.1006/viro.2002.1609. PMID: 12429523.
10: Osorio Y, Ghiasi H. Comparison of adjuvant efficacy of herpes simplex virus
type 1 recombinant viruses expressing TH1 and TH2 cytokine genes. J Virol. 2003
May;77(10):5774-83. doi: 10.1128/jvi.77.10.5774-5783.2003. PMID: 12719570;
PMCID: PMC154018.
11: Osorio Y, Wechsler SL, Nesburn AB, Ghiasi H. Reduced severity of
HSV-1-induced corneal scarring in IL-12-deficient mice. Virus Res. 2002
Dec;90(1-2):317-26. doi: 10.1016/s0168-1702(02)00249-6. PMID: 12457985.
12: Ghiasi H, Osorio Y, Nesburn AB, Wechsler SL. Enhanced clearance of herpes
simplex virus type 1 and reduced herpetic eye disease in STAT6 knockout mice is
associated with increased IL-2. Virology. 2002 Oct 25;302(2):286-93. doi:
10.1006/viro.2002.1611. PMID: 12441072.
13: Osorio Y, Cohen J, Ghiasi H. Improved protection from primary ocular HSV-1
infection and establishment of latency using multigenic DNA vaccines. Invest
Ophthalmol Vis Sci. 2004 Feb;45(2):506-14. doi: 10.1167/iovs.03-0828. PMID:
14744892.
14: Osorio Y, Cai S, Ghiasi H. Treatment of mice with anti-CD86 mAb reduces CD8+
T cell-mediated CTL activity and enhances ocular viral replication in
HSV-1-infected mice. Ocul Immunol Inflamm. 2005 Apr-Jun;13(2-3):159-67. doi:
10.1080/09273940490518775. PMID: 16019675.
15: Ghiasi H, Osorio Y, Perng GC, Nesburn AB, Wechsler SL. Recombinant herpes
simplex virus type 1 expressing murine interleukin-4 is less virulent than wild-
type virus in mice. J Virol. 2001 Oct;75(19):9029-36. doi:
10.1128/JVI.75.19.9029-9036.2001. PMID: 11533166; PMCID: PMC114471.
codelivering interleukin-12p35 as a molecular adjuvant enhances the protective
immune response against ocular HSV-1 challenge. J Virol. 2005
Mar;79(6):3297-308. doi: 10.1128/JVI.79.6.3297-3308.2005. PMID: 15731224; PMCID:
PMC1075685.
2: Mott KR, Osorio Y, Brown DJ, Morishige N, Wahlert A, Jester JV, Ghiasi H. The
corneas of naive mice contain both CD4+ and CD8+ T cells. Mol Vis. 2007 Sep
28;13:1802-12. PMID: 17960132.
3: Osorio Y, Mott KR, Jabbar AM, Moreno A, Foster TP, Kousoulas KG, Ghiasi H.
Epitope mapping of HSV-1 glycoprotein K (gK) reveals a T cell epitope located
within the signal domain of gK. Virus Res. 2007 Sep;128(1-2):71-80. doi:
10.1016/j.virusres.2007.04.007. Epub 2007 May 11. PMID: 17499382; PMCID:
PMC2020453.
4: Osorio Y, La Point SF, Nusinowitz S, Hofman FM, Ghiasi H. CD8+-dependent CNS
demyelination following ocular infection of mice with a recombinant HSV-1
expressing murine IL-2. Exp Neurol. 2005 May;193(1):1-18. doi:
10.1016/j.expneurol.2004.12.004. PMID: 15817260.
5: Mott KR, Perng GC, Osorio Y, Kousoulas KG, Ghiasi H. A recombinant herpes
simplex virus type 1 expressing two additional copies of gK is more pathogenic
than wild-type virus in two different strains of mice. J Virol. 2007
Dec;81(23):12962-72. doi: 10.1128/JVI.01442-07. Epub 2007 Sep 26. PMID:
17898051; PMCID: PMC2169076.
6: Ghiasi H, Osorio Y, Perng GC, Nesburn AB, Wechsler SL. Overexpression of
interleukin-2 by a recombinant herpes simplex virus type 1 attenuates
pathogenicity and enhances antiviral immunity. J Virol. 2002 Sep;76(18):9069-78.
doi: 10.1128/jvi.76.18.9069-9078.2002. PMID: 12186890; PMCID: PMC136420.
7: Mott KR, Osorio Y, Maguen E, Nesburn AB, Wittek AE, Cai S, Chattopadhyay S,
Ghiasi H. Role of anti-glycoproteins D (anti-gD) and K (anti-gK) IgGs in
pathology of herpes stromal keratitis in humans. Invest Ophthalmol Vis Sci. 2007
May;48(5):2185-93. doi: 10.1167/iovs.06-1276. PMID: 17460278.
8: Osorio Y, Cai S, Hofman FM, Brown DJ, Ghiasi H. Involvement of CD8+ T-cells
in exacerbation of corneal scarring in mice. Curr Eye Res. 2004 Aug-
Sep;29(2-3):145-51. doi: 10.1080/02713680490504632. PMID: 15512961.
9: Ghiasi H, Osorio Y, Hedvat Y, Perng GC, Nesburn AB, Wechsler SL. Infection of
BALB/c mice with a herpes simplex virus type 1 recombinant virus expressing IFN-
gamma driven by the LAT promoter. Virology. 2002 Oct 10;302(1):144-54. doi:
10.1006/viro.2002.1609. PMID: 12429523.
10: Osorio Y, Ghiasi H. Comparison of adjuvant efficacy of herpes simplex virus
type 1 recombinant viruses expressing TH1 and TH2 cytokine genes. J Virol. 2003
May;77(10):5774-83. doi: 10.1128/jvi.77.10.5774-5783.2003. PMID: 12719570;
PMCID: PMC154018.
11: Osorio Y, Wechsler SL, Nesburn AB, Ghiasi H. Reduced severity of
HSV-1-induced corneal scarring in IL-12-deficient mice. Virus Res. 2002
Dec;90(1-2):317-26. doi: 10.1016/s0168-1702(02)00249-6. PMID: 12457985.
12: Ghiasi H, Osorio Y, Nesburn AB, Wechsler SL. Enhanced clearance of herpes
simplex virus type 1 and reduced herpetic eye disease in STAT6 knockout mice is
associated with increased IL-2. Virology. 2002 Oct 25;302(2):286-93. doi:
10.1006/viro.2002.1611. PMID: 12441072.
13: Osorio Y, Cohen J, Ghiasi H. Improved protection from primary ocular HSV-1
infection and establishment of latency using multigenic DNA vaccines. Invest
Ophthalmol Vis Sci. 2004 Feb;45(2):506-14. doi: 10.1167/iovs.03-0828. PMID:
14744892.
14: Osorio Y, Cai S, Ghiasi H. Treatment of mice with anti-CD86 mAb reduces CD8+
T cell-mediated CTL activity and enhances ocular viral replication in
HSV-1-infected mice. Ocul Immunol Inflamm. 2005 Apr-Jun;13(2-3):159-67. doi:
10.1080/09273940490518775. PMID: 16019675.
15: Ghiasi H, Osorio Y, Perng GC, Nesburn AB, Wechsler SL. Recombinant herpes
simplex virus type 1 expressing murine interleukin-4 is less virulent than wild-
type virus in mice. J Virol. 2001 Oct;75(19):9029-36. doi:
10.1128/JVI.75.19.9029-9036.2001. PMID: 11533166; PMCID: PMC114471.
Timeline
Research Associate II
Cedars Medical Center
03.2001 - 06.2008
Medicine
Universidad Autonoma De Guadalajara