YILAI XU
Ithaca,NY
Summary
A researcher who investigates the impact of protein post-translational modifications such as palmitoylation, N-myristoylation, and phosphorylation on protein localization, protein-protein interactions, and signaling pathways.
Overview
7
7
years of professional experience
Work History
Research Assistant
Professor Hening Lin
10.2018 - Current
- Developed research protocols and procedures to produce accurate results.
- Collaborated with multidisciplinary teams to develop innovative research methodologies and strategies.
- Reviewed documents and data to identify trends and patterns.
- Coordinated and managed laboratory projects and experiments.
- Attended seminars and symposiums to improve overall knowledge and understanding.
- Trained and supervised junior technicians in laboratory protocols.
- Operated and performed preventative maintenance on laboratory equipment and instruments.
- Presented research findings at conferences.
Student Research Assistant
Professor Hilkka I. Kenttämaa
09.2016 - 05.2018
- Expanded knowledge base through active participation in conferences, workshops, and seminars relevant to the field of study.
- Presented research findings at departmental meetings, promoting awareness of current projects within the academic community.
- Assisted in the completion of research projects, conducting literature reviews and gathering relevant information.
- Mass spec training and maintenance
- HPLC training and maintenance
- Free radical reaction
Education
Ph.D. - Chemical Biology
Cornell University
Ithaca, NY05.2024
Bachelor of Science - Chemistry
Purdue University
West Lafayette, IN05.2018
Bachelor of Science - Biochemistry
Purdue University
West Lafayette, IN05.2018
Skills
- Database Research
- Scientific Writing
- Western blot
- Peptide enzymatic reactions
- Immunofluorescence
- Mass spec
- HPLC
- Mice study (oral gavage, dissection, experiment design)
- Alkyne labeling
- Acyl-biotin exchange
- Protein purification
- Cloning
- Site-mutagenesis
- qPCR
- Immune cell differentiation
Accomplishments
Zhang, Mingming, et al. "A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis." Nature 586.7829 (2020): 434-439.
Xu, Yilai, and Hening Lin. "Use of alkyne-tagged myristic acid to detect N-terminal myristoylation." Methods in Enzymology 684 (2023): 191-208.
Liu, Yinong, et al. (in press). "MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity." Science Advances.
Languages
Chinese (Mandarin)
Native or Bilingual
English
Full Professional
Timeline
Research Assistant
Professor Hening Lin
10.2018 - Current
Student Research Assistant
Professor Hilkka I. Kenttämaa
09.2016 - 05.2018
Ph.D. - Chemical Biology
Cornell University
Bachelor of Science - Chemistry
Purdue University
Bachelor of Science - Biochemistry
Purdue University
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