Yujie Chen

Responsible and motivated student ready to apply education in the workplace. Offers excellent technical abilities with software and applications, ability to handle challenging work, and excellent time management skills.

• 06/12/2023, From Cells to Fins: Single-Cell Analysis of Chromatin Accessibility and Transcriptome Dynamics During Zebrafish Caudal Fin Regeneration, The Gordon Research Conference - Genome Architecture in Cell Fate and Disease, 07/23/2022, Charting the Epigenetic Dynamics during Zebrafish Fin Regeneration at Single-Cell Resolution, 17th International Zebrafish Conference workshop, 06/22/2022, Charting the Epigenetic Dynamics during Zebrafish Fin Regeneration at Single-Cell Resolution, 2022 Midwest Zebrafish conference, 06/16/2021, Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish, 16th International Zebrafish Conference (IZFC), Remotely, 04/09/2019, Reflection on iridophore cell fate, The Gordon Research Conference - Cancer Genetics and Epigenetics, Italy, 06/07/2019, Epigenetic dynamics in zebrafish pigment cell differentiation, Midwest Zebrafish Meeting at University of Kentucky, Lexington, Kentucky, 07/23/2022, Nuances in generating and analyzing single-cell multiome data for zebrafish, 17th International Zebrafish Conference workshop, 01/31/2022, Charting epigenetic dynamics during zebrafish caudal fin regeneration at single-cell resolution, Zebrafish Group Meeting at Washington University in St. Louis, Missouri, 02/22/2021, Charting epigenetic dynamics during zebrafish caudal fin regeneration at single-cell resolution, Zebrafish Group Meeting at Washington University in St. Louis, Missouri, 10/11/2019, Epigenetic regulation in zebrafish pigment cell differentiation A reflection on iridophore cell fate, MGG/HSG/CSB Program Retreat talk at Washington University in St. Louis, Missouri, 09/2020, The role of DNA methylation in defining cell identity during zebrafish fin regeneration, Micro-grant application, Zebrafish Models for Pediatric Research, Zebrafish Research Cooperative, 05/2019, Charting the epigenetic landscape of pigment cell differentiation, Micro-grant application, Zebrafish Models for Pediatric Research, Zebrafish Research Cooperative, Lee HJ, Hou Y, Maeng JH, Shah NM, Chen Y, Lawson HA, Yang H, Yue F, Wang T, Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish, Genome Res (2022), Hyo Sik Jang
• Yujie Chen
• Jiaxin Ge, Alicia N. Wilkening, Yiran Hou, Hyung Joo Lee, You Rim Choi Rebecca F. Lowdon, Xiaoyun Xing, Daofeng Li, Charles K. Kaufman, Stephen L. Johnson, Ting Wang, Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish, Genome Biology (2021)
• Co-equal authorship, Yiran Hou, Hyung Joo Lee, Yujie Chen, Jiaxin Ge, Fujr Osman Ibrahim Osman, Anthony R. McAdow, Mayssa H. Mokalled, Stephen L. Johnson, Guoyan Zhao, Ting Wang, Celluar diversity of the regenerating caudal fin, Science Advances (2020), Hyung Joo Lee, Yiran Hou, Yujie Chen, Zea Z. Daily, Aiyana Riddihough, Hyo Sik Jang, Ting Wang, and Stephen L. Johnson, Lineage-specific DNA methylation is associated with fate restriction during regeneration, Genome Biology (2020), Vasavi Sundaram, Mayank NK Choudhary, Xiaoyun Xing, Chris Fiore, Manishi Pandey, Brett Maricque, Methma Udawatta, Duc Ngo, Yujie Chen, Asia Paguntalan, Tammy Ray, Ava Hughes, Barak A Cohen, and Ting Wang, Functional cis-regulatory modules encoded by species-specific endogenous retrovirus, Nature Communications (2017), Yanli Ren, Yujie Chen, Xue Liang, Yan Lu, Wenting Pan, Ming Yang, MiRNA-638 promotes autophagy and malignant phenotypes of cancer cells via directly suppressing DACT3, Cancer Letters (2017)

• 05/2018, Present, Thesis Research, Laboratory of Ting Wang, Department of Genetics, Washington University in St. Louis, Identify common and specific gene regulatory programs in zebrafish caudal fin regeneration at single-cell resolution, Identify epigenetic mechanism of pigment cell differentiation in zebrafish
• 02/2018, 05/2018, Rotation Research, Laboratory of Ting Wang, Department of Genetics, Washington University in St. Louis, scATAC-seq application in cell type identification
• 11/2017, 02/2018, Rotation Research, Laboratory of Zhongsheng You, Department of Cell Biology & Physiology, Washington University in St. Louis, Novel function of TCAF1 in protecting stressed replication forks in cancer cells, Role of TREX1 in replication stress response and R-loop regulation in cancer cells
• 09/2017, 11/2017, Rotation Research, Laboratory of Dr. Luis F.Z. Batista, Department of Medicine & Hematology Division, Washington University in St. Louis, Regulation of telomerase in human stem cells and its application in human diseases
• 09/2016, 01/2017, Research Assistant, Laboratory of Dr. Ming Yang, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong University, Determine the interaction of lncRNA with miRNA in autophagy and oncogenesis
• 03/2015, 06/2016, Undergraduate Research, Laboratory of Dr. Ming Yang, College of Life Science and Technology, Beijing University of Chemical Technology, Determine the function of miR-204-3p in cell proliferation, invasion and migration in esophageal cancer cells
• 07/2015, 09/2015, Summer Intern Research, Laboratory of Dr. Ting Wang, Department of Genetics, Washington University in St. Louis, Determine the role of transposable elements as cis-regulatory module using reporter gene assay
• 07/2014, 08/2014, Summer Intern Student, Laboratory of Dr. Jianguo Ji, National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Introduced to a proteomics project addressing mitochondria degradation mechanisms by autophagy

12/2018, Present, Mentor, Undergraduate students/high school students, Wang lab, Washington University in St. Louis