Yutong Liu

Therapeutic Compounds and Methods, Yutong Liu, Gunda I. Georg, Provisional patent, 63/672,087

• Development of CatSper Inhibitors as Nonhormonal Male Contraceptive Agents, Y. Liu, G. Sanchez, G. Blanco, G. Georg, Rho Chi Research Day, Minneapolis, MN, 02/2024
• Developing Inhibitors of Cation Channels of Sperm (CatSper) for Nonhormonal Male Contraception, Y. Liu, E. J. Carlson, R. Francis, P. Li, M. Lyon, C. Santi, J. Hook, J. Hawkinson, G. I. Georg, Medicinal Chemistry Seminar, Minneapolis, MN, 08/2022
• Developing Inhibitors of Cation Channels of Sperm (CatSper) for Nonhormonal Male Contraception, Y. Liu, E. J. Carlson, R. Francis, P. Li, M. Lyon, C. Santi, J. Hook, J. Hawkinson, G. Georg, Chemistry-Biology Interface Training Grant (CBITG) Symposium, Minneapolis, MN, 05/2022
• Developing Inhibitors of Cation Channels of Sperm (CatSper) for Nonhormonal Male Contraception, Y. Liu, E. J. Carlson, R. Francis, P. Li, M. Lyon, C. Santi, J. Hook, J. Hawkinson, G. Georg, Chemical Biology Interest Group (CBIG), Minneapolis, MN, 04/2022

• Working Buddy, For first-year graduate student in Department of Medicinal Chemistry, University of Minnesota, 09/2024, present
• Lab Mentor, For first-year graduate rotating students in the Georg Lab: Developed short-term rotating projects, provided instruction in synthetic techniques, and guided students through successful project completion., 10/2022, 10/2024
• Student Host, For prospective student recruitment, Department of Medicinal Chemistry, University of Minnesota, 03/2021, 03/2022
• Teacher, Aide Autistic Children Center, Nanjing, China, 07/2016
• Tour Guide, Nanjing, China, The City Wall of Ming Dynasty, 03/2016, 07/2016

• E. Carlson, R. Francis, Y. Liu, P. Li, M. Lyon, C. Santi, D. Hook, J. Hawkinson, G. I. Georg, 2022, Discovery and Characterization of Multiple Classes of Human CatSper Blockers, ChemMedChem, 17, 15, https://doi.org/10.1002/cmdc.202000499
• Y. Liu, G. Sanchez, G. Blanco, G. I. Georg, SAR Analysis of Novel CatSper Inhibitors, In preparation
• Y. Liu, G. Sanchez, G. Blanco, G. I. Georg, Design, Synthesis, and Evaluation of KSper Inhibitors for Nonhormonal Male Contraception, In preparation
• S. Syeda, Y. Liu, N. Cheryala, G. Sanchez, G. Blanco, G. I. Georg, In vivo Evaluation of Testis-specific Na+/K+ ATPase α4 Inhibitor SS-I-54 for Non-hormonal Male Contraception, In preparation

Design, Synthesis, and Evaluations of Sperm-specific Ion Channel Inhibitors for Nonhormonal Male Contraception, 02/2020, present, NIH/NICHD: 1R61HD114221, Prof. Gunda I. Georg, University of Minnesota, Six novel scaffolds were validated as CatSper inhibitors through in-house high-throughput screening. Semi-synthesis of an Ouabain Analog, SS-I-54, as a Na+/K+ ATPase α4 Inhibitor, 04/2022, 04/2023, Prof. Gunda I. Georg, University of Minnesota, An ouabain analog, SS-I-54, was synthesized through an optimized 11-step route.

• 2022, Bighley Fellowship, Awarded to full-time PhD graduate students at the College of Pharmacy who have great potential and are conducting research in basic and applied pharmaceutical sciences.
• 2018, Outstanding Student Scholarship for International Exchange Program, Highest-level of prize given to students who were in an international exchange program, based on GPA, written summary and oral presentation on the program experience, and the feedback from the partner university.
• 2017, Second Prize Scholarship, China Pharmaceutical University, Top 5% in academic performance.
• 2016, National Scholarship for Outstanding Undergraduate Student, Top 1% in academic performance.

• Developing Inhibitors of Cation Channels of Sperm (CatSper) for Nonhormonal Male Contraception, Y. Liu, G. Sanchez, G. Blanco, G. Georg, National Contraception Meeting, Houston, TX, 11/2023
• Developing Inhibitors of Cation Channels of Sperm (CatSper) for Nonhormonal Male Contraception, Y. Liu, G. Sanchez, G. Blanco, G. Georg, MIKIW Meeting, Minneapolis, MN, 04/2023
• Developing Inhibitors of Cation Channels of Sperm (CatSper) for Nonhormonal Male Contraception, Y. Liu, E. J. Carlson, R. Francis, P. Li, M. Lyon, C. Santi, J. Hook, J. Hawkinson, G. Georg, ACS Fall, Chicago, IL, 08/2022
• Developing Inhibitors of Cation Channels of Sperm (CatSper) for Nonhormonal Male Contraception, Y. Liu, E. J. Carlson, R. Francis, P. Li, M. Lyon, C. Santi, J. Hook, J. Hawkinson, G. Georg, MIKIW Meeting, Iowa City, IA, 04/2022