Abdulrahman Jama

Dynamic research fellow analyst with a proven track record in conducting insightful research and analysis. Experienced in gathering and interpreting data, identifying trends, and providing strategic recommendations. Strong analytical skills, attention to detail, and a passion for driving innovation and excellence in research initiatives.

Graduate Student Excellence Award, 2018, Awarded to outstanding students in the master’s program in the Biochemistry and Molecular Biology department.

• Jama, Abdulrahman, et al., Exploring lipin1 as a promising therapeutic target for the treatment of Duchenne muscular dystrophy., Journal of Translational Medicine, 22, 1, 07/16/24, https://doi.org/10.1186/s12967-024-05494-z
• Jama, Abdulrahman, et al., Lipin1 Plays Complementary Roles in Myofibre Stability and Regeneration in Dystrophic Muscles., The Journal of Physiology, 601, 5, 2023, 961–978, https://doi.org/10.1113/jp284085
• Ramani Sattiraju, Sandhya, et al., Loss of Membrane Integrity Drives Myofiber Death in lipin1‐Deficient Skeletal Muscle., Physiological Reports, 8, 20, 2020, https://doi.org/10.14814/phy2.14620
• Miranda, Daniel R., et al., Mechanisms of Altered Skeletal Muscle Action Potentials in the R6/2 Mouse Model of Huntington’s Disease., American Journal of Physiology-Cell Physiology, 319, 1, 2020, https://doi.org/10.1152/ajpcell.00153.2020
• Jama A, Huang D, Alshudukhi AA, Chrast R, Ren H., Lipin1 is required for skeletal muscle development by regulating MEF2c and MyoD expression., J Physiol., 02/2019, 597, 3, 889-901, 10.1113/JP276919
• Chamberlin HM, Jain IM, Corchado-Sonera M, Kelley LH, Sharanya D, Jama A, Pabla R, Dawes AT, Gupta BP., Evolution of Transcriptional Repressors Impacts Caenorhabditis Vulval Development., Mol Biol Evol., 05/01/2020, 37, 5, 1350-1361, 10.1093/molbev/msaa009
• Alshudukhi AA, Zhu J, Huang D, Jama A, Smith JD, Wang QJ, Esser KA, Ren H., Lipin-1 regulates Bnip3-mediated mitophagy in glycolytic muscle., FASEB J., 12/2018, 32, 12, 6796-6807, 10.1096/fj.201800374
• Mahalak KK, Jama AM, Billups SJ, Dawes AT, Chamberlin HM., Differing roles for sur-2/MED23 in C. elegans and C. briggsae vulval development., Dev Genes Evol., 06/2017, 227, 3, 213-218, 10.1007/s00427-017-0577-4

• Dr. Hongmei Ren, Ph.D., Biochemistry and Molecular Biology, Wright State University, 3640 Colonel Glenn Hwy, 135 Diggs Laboratory, Dayton, OH, 45435, 937-775-4693, Hongmei.ren@wright.edu
• Dr. Weiwen Long, Ph.D., Biochemistry and Molecular Biology, Wright State University, 3640 Colonel Glenn Hwy, 112 Diggs Laboratory, Dayton, OH, 937-775-3172, weiwen.long@wright.edu
• Dr. Mark Rich, Ph.D., Neuroscience Cell Biology and Physiology, Wright State University, 3640 Colonel Glenn Hwy, 313 NEC Building, Dayton, OH, 937-775-2234, mark.rich@wright.edu

• AAV.U7snRNA: an efficient vectorized DMD exon 44 skipping for 6-12% of DMD patients - Minimal efficacious dose and dual injection studies
  , NCH’s 27th Annual Research Retreat at The Ohio State Union
• AAV.U7.4XSD44 Delivery Mediates Efficient Exon 44 Skipping in Δ45 DMD Mice Model, Research in Progress, Center for Gene Therapy, Nationwide Children’s Hospital, 08/02/24
• Lipin1 Regulates Myoblast Differentiation through the MyoD-Mef2c-HDAC5 Axis, Ohio Physiological Society, 09/21/19

• Doctoral Research, Wright State University, Dayton, OH, 2018-2023, Dr. Hongmei Ren, Ph.D., Generated Dystrophin-Lipin1 double knockout mice., Generated mdx:lipin1 transgenic mice., Utilized in vivo to deliver Lipin1 expression to mdx primary myocytes using AAV system.
• Master’s Research, Wright State University, Dayton, OH, 2016-2018, Dr. Hongmei Ren, Ph.D., Characterized the role of lipin1 in skeletal muscle by conditionally knocking out Lipin1 expression in skeletal muscle.
• Research Assistant, Ohio State University, Columbus, OH, 2014-2016, Dr. Helen Chamberlin, Department of Molecular Genetics, Investigate the role of Hmg3/4 and DMD 4/5 in Caenorhabditis elegans development., Investigate Lin-1, an MAP-kinase mediated signaling protein and its phosphorylation rate between two nematodes, C elegans vs C briggsae., The biochemical differences of Spr-4 and Htz-1 genes in C elegans vs. C briggsae in respect to multivulva development.

• Graduate Student Excellence Award
• Best Poster - Postdoctoral Scientists