Akshada Shinde
West Lafayette,IN
Summary
Being a part of Toxicology family since past 3 years, I consider learning as an iterative process with self-analysis on every task I do and strive constantly to improve further. I am a PhD student in the department of Health Sciences (Toxicology) at Purdue University. With scientific acuity and sound technical knowledge, I can implement the same while working and have the ability to troubleshoot the problems raised during the research methodologies. I am capable of working efficiently both in group and individually. Striving to leverage my Toxicological skills in Research and Development.
Overview
6
6
years of professional experience
Work History
Graduate Research Assistant (PhD Student)
Purdue University
West Lafayette, IN
08.2022 - Current
- Research focuses on nanoparticle exposure-induced inflammatory signaling in the metabolic syndrome disease state.
- Besides, I work on side projects involving electronic nicotine delivery system-induced oral health effects.
- Working with an external industry project supported by Eli Lilly company, majorly focusing on nanomedicine research and development.
- Utilizes animal models (mice), cell culture models, and human samples.
- Attended professional conferences to present research findings and network with peers in the field.
Scientist, Toxicology
Kenvue Inc. (Former Johnson and Johnson Pvt. Ltd)
Mumbai, Maharashtra, India
05.2021 - 05.2022
- Toxicology Review and Safety Assessments of Raw Materials and
- Finished products, mainly supporting Skin Care, Beauty, and Baby products for Global projects, mainly including the EMEA region.
- Understanding and drafting the finer details of Consumer Products Safety Assessments for cosmetic products.
- Literature search for toxicity/safety data of ingredients/impurities.
- Preparation of Toxicological Profiles for Raw Material, Ingredients, and Impurities
- Collaborate/partner with other toxicology colleagues, raw material center, and product development partners for project needs and support.
- Understanding the basics and supporting projects using predictive toxicology tools like the OECD QSAR Toolbox and Toxtree (recent versions).
Junior Research Associate
Sa-FORD (Sanctuary for Research and Development)
Mumbai, Maharashtra, India
07.2019 - 03.2020
- Study Personnel in Non-Clinical Health and Environmental Safety Studies in animals.
- Conducted the Reproductive Toxicity studies with sound knowledge of chronic toxicity and reproductive toxicity studies.
- Conducted the Developmental Toxicity studies in Rats. Involved in long-term toxicity studies, including carcinogenicity studies.
- Sound knowledge of dose preparation and dose formulation.
- Well versed in OECD Toxicity guidelines. Acquainted with the Good Laboratory Practices (GLP) principles and Standard Operating Procedures of GLP.
Trainee Toxicology
ClinChoice (Former iMED Global Solutions, Pvt. Ltd
Hyderabad , India
07.2018 - 06.2019
- Toxicology Review and Safety Assessment of Skin Sensitization Endpoint for deriving No Expected Sensitizing Induction Level (NESIL) values
- Toxicology Review and Safety Assessment: Data gaps on Systemic Toxicity studies and deriving No Expected Adverse Effect, Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL)
- Preparation of INCI Tox Profiles for various cosmetic ingredients.
- Well versed with predictive Tox tools like the OECD QSAR Toolbox.
- Toxtree for Structure Analysis of Chemicals.
Education
Ph.D. - Toxicology
Purdue University
West Lafayette, INMaster of Science - Regulatory Toxicology
National Institute of Education And Research
Hyderabad, India 06-2018
Bachelor of Pharmacy - Pharmaceutical Sciences
NDMVP College of Pharmacy, Pune University
Nashik, India05-2016
Skills
- Animal Care and Handling
- Animal Dosing (Oral, Intravenous, Intraperitoneal; Rats and Mice)
- Animal Necropsy and Dissection
- Handling appartus and tools like Western blotting apparatus, Chemiluminescence images, PCR instruments, Plate readers
- Knowledge in various animal models in Pharmacological Screening and In-vitro methods
- Microsoft Office (Word, Excel, Powerpoint, Outlook), Graph Pad Prism, OECD QSAR Toolbox and Toxtree, ChemDraw (Basics)
- Strong Academic Record, Self-Directed and Motivated, Teamwork and Collaboration, Presentation Skills, Critical thinking ability, etc
Publications
- Jeon, J., He, X., Shinde, A. et al. The role of puff volume in vaping emissions, inhalation risks, and metabolic perturbations: a pilot study. Sci Rep 14, 18949 (2024).
- Shinde A and Shannahan J (2024) Inhalation exposure-induced toxicity and disease mediated via mTOR dysregulation. Exp. Biol. Med. 249:10135. doi: 10.3389/ebm.2024.10135
- Jeon, J., Shinde, A., Chepaitis, P., Cushenan, P., Zhang, Q., Weaver, S., Luo, R., Black, M., Shannahan, J., Wright, C., Variances in Vaping Behavior Contribute to Adverse Periodontal Health Effects, Society of Toxicology (SOT) Abstract
- Ashutosh Kumar, Amruta Dhawan, Alknanda Kadam and Akshada Shinde, Autophagy and Mitochondria: Targets in Neurodegenerative Disorders, CNS and Neurological disorders - Drug Targets; Nov, 2018,1;17(9)
Accomplishments
- Nanoscience and Advanced Materials Specialty Section (NAMSS) Outstanding Graduate Student Award, Society of Toxicology (SOT), 2024
- Akshada Shinde, Arjun Pitchai, Li Xia, Christina Ferreira, Jonathan Shannahan. Lipid-Mediated Inflammation Contributes to Metabolic Syndrome-Associated Pulmonary Susceptibility Nanoparticles. College of Human and Health Sciences (HSCI) Research Retreat 2024, Purdue University. PpPhD Poster Award
- Akshada Shinde, Arjun Pitchai, Li Xia, Christina Ferreira, Jonathan Shannahan. Lipid-Mediated Inflammation Contributes to Metabolic Syndrome-Associated Pulmonary Susceptibility Nanoparticles. Ohio Valley Society of Toxicology Annual Meeting (OVSOT), 2023, Purdue University. Pp**3rd place for PhD Poster Presentation
- Akshada Shinde, Li Xia, Arjun Pitchai, Christina Ferreira, Jonathan Shannahan. Lipid Mediated Inflammation Regulates Metabolic Syndrome-Associated Susceptibility to Inhaled Nanoparticles. College of Human and Health Sciences (HSCI) Research Retreat 2023, Purdue University. Pp**2nd Place for Early Researcher Award.
Teaching Experience
- HSCI 575, Introduction To Environmental Health, Teaching Assistant - Spring 2024 Purdue University, West Lafayette, IN
- HSCI 560, Toxicology, Teaching Assistant - Fall 2023 Purdue University, West Lafayette, IN
Affiliations
- Vice President of Graduate Student Organization (GSO) Committee, School of Health Sciences, Purdue University 2024-25
- Social Chair of the Graduate Student Organization (GSO) Committee, School of Health Sciences, Purdue University 2023-24
Languages
English
Full Professional
Hindi
Full Professional
Marathi
Native/ Bilingual
Timeline
Graduate Research Assistant (PhD Student)
Purdue University
08.2022 - Current
Scientist, Toxicology
Kenvue Inc. (Former Johnson and Johnson Pvt. Ltd)
05.2021 - 05.2022
Junior Research Associate
Sa-FORD (Sanctuary for Research and Development)
07.2019 - 03.2020
Trainee Toxicology
ClinChoice (Former iMED Global Solutions, Pvt. Ltd
07.2018 - 06.2019
Ph.D. - Toxicology
Purdue University
Master of Science - Regulatory Toxicology
National Institute of Education And Research
Bachelor of Pharmacy - Pharmaceutical Sciences
NDMVP College of Pharmacy, Pune University
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