Alissa Wynne
Meriden,CT
Summary
Results-driven Senior Associate Scientist with 9 years of biotech experience in cellular and molecular biology. Strong foundation in assay development and optimization, successfully leading the development of multiple cell-based and biochemical assays. Contributed data to two IND submissions while supporting cross-functional teams in fast-paced biotech settings. Recognized for strong troubleshooting skills, project ownership, and collaborative leadership. Seeking to join a growing biotech company to drive impactful therapeutic innovations.
Overview
10
10
years of professional experience
Work History
Senior Associate Scientist
Arvinas
12.2021 - Current
- Selected for promotion based on strong performance and leadership; assumed higher-level responsibilities typically assigned to Research Scientists despite funding-related freeze on title change.
- Designed and executed checkerboard drug combination assays using cancer cell lines to evaluate synergistic and antagonistic effects of PROTAC degraders with targeted therapies.
- Developed and optimized multiple cell-based proliferation and viability assays used in target validation and late-stage drug discovery
- Prepared cell lysates and conducted Western blotting to assess changes in key signaling pathways, supporting mechanism-of-action studies.
- Contributed critical data and documentation toward two IND submissions for first-in-class PROTAC therapeutics.
- Designed and implemented data analysis workflows; presented findings at internal meetings and results were featured in posters at national cancer research conferences.
- Managed multiple projects simultaneously while maintaining strict deadlines and high-quality standards.
- Spearheaded troubleshooting initiatives that resolved persistent assay variability, improving reproducibility and efficiency.
- Evaluated and implemented new technologies and laboratory techniques to improve quality and robustness of sample analysis.
- Documented protocols, experimental results, and analysis in ELNs and cross-functional team reports.
- Mentored and trained junior scientists, fostering a collaborative work environment that facilitated skill development and growth.
- Read literature related to scientific area of expertise to remain current in knowledge.
Associate Scientist
Abcam
01.2020 - 11.2021
- Led Custom Solutions phage display pipeline; delegated tasks and developed schedules to meet client deadlines.
- Performed complex troubleshooting and assisted in leading initiatives to solve challenging scientific problems with assays or instrumentation
- Compiled data and distilled large amounts of information to produce reports, spreadsheets, and documents outlining key details for distribution to appropriate stakeholders
- Mentored and trained junior scientists and new hires on processes, procedures, and lab best practices
- Highlighted experimental results for site-wide and company-wide presentations
- Developed and maintained SOPs, performed risk assessments, and coordinated multi-site material transfers.
Senior Research Associate
Abcam
01.2017 - 01.2020
- Generated high quality monoclonal antibodies for external clients via phage display pipeline
- Executed complex molecular biology techniques including PCR, cloning, ELISA, and protein purification.
- Supported NGS workflows, B-cell enrichment and selection technology (BEST), and flow cytometry for client-based projects.
- Conducted transient transfections and mammalian cell maintenance for customer projects.
Laboratory Assistant
Abcam
05.2016 - 01.2017
- Operated basic laboratory equipment such as balances, pH meter, spectrophotometer, and autoclave
- Supported inventory and equipment maintenance; promoted lab safety, organization, and cleanliness.
- Supported laboratory staff with advanced troubleshooting, resolving complex problems and helping with special projects
Graduate Assistant
University Of New Haven
08.2015 - 05.2017
- Trained students in aseptic cell culture technique; maintained adherent commercial cell lines.
- Supported laboratory course setup, SOP revisions, and equipment training for undergraduates.
- Managed administrative tasks for courses
Senior Associate Scientist
Arvinas
12.2021 - Current
- Selected for promotion based on strong performance and leadership; assumed higher-level responsibilities typically assigned to Research Scientists despite funding-related freeze on title change.
- Developed and optimized multiple cell-based and biochemical assays used in target validation and drug screening programs.
- Contributed critical data and documentation toward two IND submissions for first-in-class PROTAC therapeutics.
- Designed analysis workflows that streamlined data interpretation for preclinical studies; results were featured in posters at national cancer research conferences.
- Spearheaded troubleshooting initiatives that resolved persistent assay variability, improving reproducibility and efficiency.
- Evaluated and implemented new technologies and laboratory techniques to improve quality and robustness of sample analysis.
- Performed complex troubleshooting and assisted in leading initiatives to solve challenging scientific problems with assays or instrumentation.
- Read literature related to scientific area of expertise to remain current in knowledge.
- Trained new employees on areas of technical expertise and compliance issues relevant to lab setting.
- Conducted moderately complex analysis to support process development.
Education
Master of Science - Cellular and Molecular Biology
University of New Haven
West Haven, CT05.2017
Bachelor of Science - Biology Pre-Medical and Forensic Science
University of New Haven
West Haven, CT05.2015
Skills
- Experimental design
- Mammalian cell maintenance
- Cell proliferation assays
- SDS-PAGE
- Western blot
- ELISA
- Transient transfections
- Experience with Incucyte platforms
Timeline
Senior Associate Scientist
Arvinas
12.2021 - Current
Senior Associate Scientist
Arvinas
12.2021 - Current
Associate Scientist
Abcam
01.2020 - 11.2021
Senior Research Associate
Abcam
01.2017 - 01.2020
Laboratory Assistant
Abcam
05.2016 - 01.2017
Graduate Assistant
University Of New Haven
08.2015 - 05.2017
Master of Science - Cellular and Molecular Biology
University of New Haven
Bachelor of Science - Biology Pre-Medical and Forensic Science
University of New Haven
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