Amber Chen
Summary
QC Associate Analyst with many years of experience in biochemistry. Have been working on related projects since university. Have a strong interest in CAR-T cell therapy and very optimistic about the prospect of such treatment method. Skilled in research and lab working.
Overview
2
2
years of professional experience
Work History
QC Associate Analyst II
CARsgen Therapeutics
11.2022 - Current
- Conduct bench analysis including cell culture, flow cytometry, cell viability determination, ELISA, and qPCR under the guidance of cGMP, GLP, and corporate procedures.
- Participate in QC Bioassay Laboratory operations including the laboratory equipment maintenance, laboratory reagent and inventory management, data review, and training.
- Facilitate laboratory investigations including invalid assays, deviations, and OOS/OOT.
- Author, review and revise SOPs and Work Instructions for chemistry and biochemistry methods.
Research Assistant
CARsgen Therapeutics
06.2021 - 11.2022
- Design, optimize and validate CRISPR knockout gRNA to discovery effective gene editing targets of allogenic CAR-T;
- Detect CRISPR on-target efficiency by ICE and NGS sequencing;
- Test gRNA activity at the protein and gene levels, predict off-target risk through WGS analysis;
- Assisted supervisors in the construction of high-throughput sequencing platforms according to the project requirements;
- Culture CAR-T cells and do functional experiment.
- Applied for one patent for generic CAR-T related invention (patent application number: CN202210443135.X) as one of the inventors in April 2022
Education
Master of Science - Pharmacognosy
China Pharmaceutical University
Nanjing, China06.2021
Bachelor of Science - Chinese Materia Medica
Heilongjiang University of Chinese Medicine
Harbin, China06.2018
Skills
- Gene editing
- CAR-T cell
- Cell Biology
- Molecular biology
- Quality control
- Data analysis
Hobbies
- Running
- Guitar
- Hiking
Timeline
QC Associate Analyst II
CARsgen Therapeutics
11.2022 - Current
Research Assistant
CARsgen Therapeutics
06.2021 - 11.2022
Master of Science - Pharmacognosy
China Pharmaceutical University
Bachelor of Science - Chinese Materia Medica
Heilongjiang University of Chinese Medicine
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