Responsible for expressing and refolding isolated SARS-COV2 receptor binding domain sequences conjugated to protein nanoparticles in applications toward manipulating drug delivery kinetics
Responsible for genetic engineering and recombinant production of a protein nanoparticle delivery system in applications toward manipulating drug delivery kinetics
Periodontal Surgical Assistant
Mardirossian Periodontics and Implant Dentistry
06.2023 - 09.2023
Working alongside lead periodontist in the application of L-PRF extract in bone & soft tissue regeneration procedures
Research and Development Internship
Spark Therapeutics
06.2022 - 08.2022
Optimized LNP formulations to screen for strong encapsulation of payload using Quant-iT PicoGreen dsDNA assay kit
LNP formulations further screened for in vitro efficacy and immunogenicity using human liver cancer cell lines and human monocyte cell lines respectively
Optimized LNP formulations with dsDNA and ssDNA to test differences in immune activation in human monocyte cell line
Assistance Adult Member
Assistance League of Tustin
06.2014 - 06.2017
Operation School Bell: providing kids in school with new uniforms for school
The Thrift Store: worked as a cashier to help with fundraising
Blue boy swim instructor for families with disabled children
Project TODAY: Providing drug kits to schools in the Tustin Unified School district
Education
Master of Science - Chemical And Biomolecular Engineering
University of California
Irvine, California
06-2025
Bachelor of Science - Biomolecular Engineering And Bioinformatics
University of California
Santa Cruz, CA
06.2023
Skills
Lipid nanoparticle formulation
Cell culture
Bacterial transformation
Protein expression and purification
PCR cloning
Restriction cloning/DNA vector cloning
Gel electrophoresis
SDS-PAGE
Nucleic acid encapsulation
Column chromatography
IR spectroscopy
DLS
NanoAssemblr ignite
IR spectrometer
Publications
Haley, D.J.; Lanning, S.; Henricson, K.E.; Mardirossian, A.A.; Cirillo, I.; Rahe, M.C.; DuBois, R.M. Structure and Antigenicity of the Porcine Astrovirus 4 Capsid Spike. Viruses2024, 16, 1596. https://doi.org/10.3390/v16101596
Timeline
Masters Student
Wang Lab
01.2024 - Current
Periodontal Surgical Assistant
Mardirossian Periodontics and Implant Dentistry
06.2023 - 09.2023
Research and Development Internship
Spark Therapeutics
06.2022 - 08.2022
Assistance Adult Member
Assistance League of Tustin
06.2014 - 06.2017
Master of Science - Chemical And Biomolecular Engineering
University of California
Bachelor of Science - Biomolecular Engineering And Bioinformatics
Research Intern at Xiangxi Wang Lab, Institute of Biophysics, Chinese Academy of SciencesResearch Intern at Xiangxi Wang Lab, Institute of Biophysics, Chinese Academy of Sciences
Business Services Administrator – Facilities Services Manager at Orange County Probation DepartmentBusiness Services Administrator – Facilities Services Manager at Orange County Probation Department