Andrew M. Dunn
Senior Research Associate, Translational Pathology
BROOKLINE,MA
Summary
Self-directed biotechnology professional working to better understand interrogating the tumor microenvironment through the immune system. Expertise in translational assay development and data analysis & interpretation from target validation to clinical immune-oncology programs. Passionate about innovative cross-functional solutions to answer scientific questions with a targeted approach. Delivers exemplary performance in fast-paced environments with strict deadlines.
Overview
4
4
years of professional experience
4
4
years of post-secondary education
2
2
Languages
Work History
Senior Research Associate, Translational Pathology
Jounce Therapeutics
Cambridge, MA
01.2021 - Current
- Optimized and validated clinical assays for predictive biomarker reproducibility and novel mechanism of action
- Developed algorithms to support fine-tuned image analysis across several tumor indications
- Conducted epidemiological screens and developed cell type identification assays for early discovery target validation
- Facilitated proof-of-feasibility studies in laser capture microdissection instrument
- Managed pathology activities for ex vivo histoculture program
- Managed cooperative education student in independent project.
Research Associate, Translational Pathology
Jounce Therapeutics
Cambridge, MA
02.2019 - 12.2020
- Optimized and validated immunohistochemistry, immunofluorescence and in situ hybridization assays for pre-clinical programs
- Performed digital image analysis for downstream statistical analysis
- Presented key data and interpretations for program team meetings
- Performed tissue processing, embedding, and sectioning.
Research Associate, Contract Research Services
Akoya Biosciences
Hopkinton, MA
11.2017 - 02.2019
- Facilitated creation and optimization of high-plex translational immunofluorescence assays based on client biomarker needs
- Consolidated images, data, and results into reports
- Updated QSOPs and improved laboratory workflow to acquire key customers
- Completed project milestones and distributed deliverables to clients ahead of schedule
- PerkinElmer's Quantitative Pathology Solutions division was acquired by Akoya Biosciences in September, 2018.
Education
Bachelor of Arts - Neuroscience
Boston University
Boston, MA 08.2013 - 05.2017
Skills
Immunohistochemistry
Immunofluorescence
In Situ Hybridization
Histology
Ex Vivo Histoculture
Laser Capture Microdissection
Image Analysis
Spotfire
Statistical Analysis
Project Management
Publications & Abstracts
Lee, Sanghoon et al. “Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer.” Cell reports vol. 31,2 (2020): 107502. doi:10.1016/j.celrep.2020.03.066
McGrath, Lara et al. “Abstract 1727: Tumor associated macrophages and resistance to immune checkpoint blockade: consideration of cancer indications for the clinical development of JTX-8064, an anti-LILRB2/ILT4monoclonal antibody” Cancer Res July 1 2021 (81) (13 Supplement) 1727; DOI: 10.1158/1538-7445.AM2021-1727
Timeline
Senior Research Associate, Translational Pathology
Jounce Therapeutics
01.2021 - Current
Research Associate, Translational Pathology
Jounce Therapeutics
02.2019 - 12.2020
Research Associate, Contract Research Services
Akoya Biosciences
11.2017 - 02.2019
Bachelor of Arts - Neuroscience
Boston University
08.2013 - 05.2017