Arash Mohtashamian, M.D.
Reno,USA
Overview
25
25
years of professional experience
Work History
Staff Pathologist / Hematopathologist
Renown Regional Medical Center
Reno, USA
03.2024 - Current
- Provide ongoing diagnostic expertise for intraoperative consultations and cytology and surgical pathology cases, ensuring accurate and timely results for patient care.
- Interpret diagnostic data from flow cytometry studies, peripheral blood smears, and bone marrow or lymph node specimens.
- Facilitate validation of new assays, overseeing design, methodology selection, performance verification, and production to support clinical testing quality.
- Collaborate with Laboratory Director to manage laboratory administration and operations, enhancing workflow efficiency and compliance with regulatory standards.
Director of Hematology
Genomic Testing Cooperative (GTC)
Irvine, USA
04.2023 - 03.2024
- Directed the diagnostic interpretation and clinical reporting of NGS panel assays, overseeing 10,000-15,000 hematologic malignancy specimens annually.
- Oversaw new assay validation, optimizing design, methodology selection, and performance verification processes to improve assay reliability.
- Led operational planning and implemented QA/QC procedures, enhancing delivery of high-quality laboratory services.
- Collaborated with Laboratory Director to streamline molecular laboratory operations, ensuring regulatory compliance and effective administrative functions.
- Managed and addressed medical and pathology-related inquiries from professional clients.
- Contributed to the field through peer-reviewed publications and presentations at national scientific conferences.
- Https://genomictestingcooperative.com
Director of Clinical Support Services & Staff Pathologist, USN (Ret. CAPT/0-6 May 2023)
US Navy, Naval Hospital, Camp Pendleton
Camp Pendleton, USA
05.2018 - 04.2023
- Established the inaugural COVID-19 molecular laboratory at Camp Pendleton, directing pandemic-response care for over 150,000 active-duty military members and beneficiaries.
- Provided diagnostic interpretation for 2,500-3,000 surgical pathology specimens and 300-400 cytology cases, ensuring accurate and timely results for patient care.
- Spearheaded quality improvement initiatives across directorate, enhancing key quality performance indicators and maintaining productivity.
- Directed budget and operational oversight for Laboratory Services, Anatomic Pathology, Radiology, Pharmacy, and Physical/Occupational Therapy as Senior Administrative Manager, managing 350 personnel and a $52 million annual operating budget.
Contract/part time surgical pathologist
Pacific Rim Pathology (Sharp Healthcare)
San Diego, USA
07.2021 - 08.2022
- Performed diagnostic evaluations for surgical pathology cases and cytology specimens, providing critical expertise during intraoperative consultations to support timely surgical decisions.
Contract/part time hematopathologist
Quest Diagnostics
San Juan Capistrano, USA
07.2011 - 07.2022
- Directed diagnostic interpretation for 500 bone marrow and lymph node specimens, 500 peripheral blood smears, and 4,000 flow cytometry studies, ensuring accurate diagnoses and treatment pathways.
- Managed triage and analysis of 5,000 molecular and immuno-oncology biomarker tests annually, including PDL1, MSI, MMR, Her2, PR, and ER, supporting personalized treatment strategies.
Navy Pathology Specialty Leader and Naval Medical Center, San Diego residency program director
US Navy, Naval Medical Center, San Diego
San Diego, USA
12.2015 - 05.2022
- Directed a global cohort of 79 staff and resident pathologists as the Pathology Consultant to the Navy Surgeon General.
- Provided expert specialty and subspecialty guidance to the Director of the Defense Health Agency and the Chief of the Bureau of Medicine and Surgery.
- Directed the ACGME-accredited, 4-year residency in Anatomic and Clinical Pathology, managing 10-12 residents.
- Authorized and endorsed all selections for fellowship and residency positions.
- Led the implementation and management of the ACGME Pathology Resident Performance Milestones and Next Accreditation System (NAS), achieving a 100% Board Certification pass rate across 6 years.
- Acted as Medical Director for the immunohistochemistry, coagulation, and hematology laboratories.
- Leveraged eight years of subspecialty sign-out expertise in genitourinary and hematopathology for adult and pediatric populations to enhance diagnostic accuracy.
- Led discussions and case evaluations as the pathologist for Genitourinary and Medical Oncology tumor boards, contributing to collaborative treatment planning.
Department head and staff pathologist
US Navy, Okinawa, Japan
Okinawa, Japan
07.2007 - 06.2009
- Directed laboratory services, managing 60 professionals and a $3 million budget, ensuring efficient operation of 800,000 laboratory tests.
- Interpreted diagnostics for 3,500 surgical pathology specimens and 4,000 cytology cases, contributing to accurate diagnoses and patient care.
- Established in-house molecular testing for H1N1/09, overseeing screening of over 1,000 service members to promptly identify infections.
General Medical Officer (GMO)
US Navy, 7th Marines, 29 Palms, California
29 Palms, USA
07.2001 - 07.2003
- Delivered comprehensive medical care to 1,500+ active-duty Marines and Sailors during combat and humanitarian missions in Iraq, Kuwait, and the Indo-Pacific Theater, ensuring readiness and health support.
- Coordinated anthrax and smallpox vaccination initiatives for over 50,000 active-duty personnel during Operation Iraqi Freedom, enhancing force protection and operational readiness.
- Led training programs for junior officers and recruits on operational protocols.
- Coordinated logistics for troop deployments and equipment transfers in the field.
- Developed standard operating procedures for mission planning and execution.
Education
Fellowship - Hematopathology
Northwestern University Feinberg School of Medicine
Chicago, IL06-2010
Residency - Anatomic and Clinical Pathology
Walter Reed National Military Medical Center
Bethesda, MD08-2007
Internship - Internal Medicine
National Naval Medical Center
Bethesda, MD06-2001
Doctor of Medicine (MD) -
The Medical College of Wisconsin
Milwaukee, WI05-2000
Dual Degrees - Biological Sciences/Biophysics and Philosophy
University of California, Irvine (UCI)
Irvine, CA06-1996
Skills
- Board-certified Anatomic and Clinical Pathologist with over 25 years of comprehensive experience and a sub-specialty in Hematopathology Proven track record of directing high-complexity laboratory operations, ensuring CAP/CLIA compliance, and leading multi-disciplinary teams in hospital and private laboratory settings Expert in integrating advanced diagnostic modalities, including flow cytometry and molecular pathology, to drive clinical excellence and operational efficiency
Credentials And Certifications
- Board Certified in Hematopathology, American Board of Pathology, 2010
- Board Certified in Anatomic and Clinical Pathology, American Board of Pathology, 2007
- California Medical License, A116553, 2011-present
- Nevada Medical License, 24484, 06/30/25
Affiliations
- American Society of Hematology (ASH)
- Association for Molecular Pathology (AMP)
- American Society of Clinical Oncology (ASCO)
- American and European Society of Hematopathology (SH/EHAP)
- United States and Canadian Academy of Pathology (USCAP)
Platform Presentations
- Performance Characteristics of Molecular Testing Platforms for SARS-CoV-2, Mohtashamian, A., Naval Hospital, Camp Pendleton, 08/01/20
- Deep Convolutional Neural Networks for Automated Diagnosis of Prostate Cancer, Olson, N., T. Hromadka, A. Mohtashamian., United States Naval Medical Center, 2017, San Diego, CA
- Case of the Quarter, Gaucher's Disease Involving Bone Marrow and Spleen, Mohtashamian, A., San Diego Society of Hematopathology, 2016, San Diego, CA
- Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type Presenting as a Post-Transplant Lymphoproliferative Disorder, Gomez, R. and A. Mohtashamian., 2015, American and European Society of Hematopathology
- Bone Marrow Morphology After Therapy and Stem Cell Transplantation, Mohtashamian, A., 2014, San Diego, CA
- Advances in Understanding of Mantle Cell Lymphoma and Role of Minimal Residual Disease Detection in Patient Management, Mohtashamian, A., 2013, San Diego, CA
- Mast Cell Sarcoma in a Patient With a History of Gamma/Delta TCell Lymphoblastic Leukemia/Lymphoma, Mohtashamian, A., 2010, Society of Hematopathology, Sweden
- 57 Year Old Man with HIV and Monoclonal Gammopathy of Undetermined Significance, Mohtashamian, A., 2010, Society of Hematopathology, Sweden
Publications
- Liquid biopsy for evaluating mutations and chromosomal aberrations in cerebrospinal fluid from patients with primary or metastatic CNS tumors., Charifa A, Agersborg S, Mohtashamian A, Ip A, Goy A, Albitar M., J Liq Biopsy, 2024, 4, 100155, 10.1016/j.jlb.2024.100155
- PathAlign: A vision-language model for whole slide images in histopathology., Faruk Ahmed, Andrew Sellergren, Lin Yang, Jinhua Xu, Boris Babenko, Abbi Ward, Niels Olson, Arash Mohtashamian, Yossi Matias, Greg Corrado, Quang Duong, Dale R. Webster, SHRAVYA SHETTY, Daniel Golden, Yun Liu, David F. Steiner, Ellery Wulczyn., Openreview.net, 2024
- Independent assessment of a deep learning system for lymph node metastasis detection on the Augmented Reality Microscope., David Jin, Joseph H. Rosenthal, Elaine E. Thompson, Jared Dunnmon, Arash Mohtashamian, Daniel Ward, Ryan Austin, Hassan Tetteh, Niels H. Olson., Journal of Pathology Informatics, 2022, 13, 100142, 10.1016/j.jpi.2022.100142
- Mast cell sarcoma trans differentiated from clonally-related T-lymphoblastic leukemia upon acquisition of TP53 mutation and genetic complexity., Gao J, Fu L, Lu X, Sukhanova M, Frankfurt O, Mohtashamian A, Chadburn A, Jennings L, Aqil B, Chen Q, Chen YH., Leuk Lymphoma, 2021, Jul 14, 1-4, 1080/10428194.2021.1950710
- Development and Validation of a Deep Learning Algorithm for Gleason Grading of Prostate Cancer From Biopsy Specimen., Nagpal K, Foote D, Tan F, Liu Y, Chen PC, Steiner DF, Manoj N, Olson N, Smith JL, Mohtashamian A, Peterson B, Amin MB, Evans AJ, Sweet JW, Cheung C, van der Kwast T, Sangoi AR, Zhou M, Allan R, Humphrey PA, Hipp JD, Gadepalli K, Corrado GS, Peng LH, Stumpe MC, Mermel CH., JAMA Oncol, 2020, Sep 1, 6, 9, 1372-1380
- Development and validation of a deep learning algorithm for improving Gleason scoring of prostate cancer., Nagpal K, Foote D, Liu Y, Chen PC, Wulczyn E, Tan F, Olson N, Smith JL, Mohtashamian A, Wren JH, Corrado GS, MacDonald R, Peng LH, Amin MB, Evans AJ, Sangoi AR, Mermel CH, Hipp JD, Stumpe MC., NPJ Digit Med, 2019, June 7, 2, 48, 1038/s41746-019-0112-2
- Artificial Intelligence-Based Breast Cancer Nodal Metastasis Detection: Insights Into the Black Box for Pathologists., Liu Y, Kohlberger T, Norouzi M, Dahl GE, Smith JL, Mohtashamian A, Olson N, Peng LH, Hipp JD, Stumpe MC., Arch Pathol Lab Med, 2019, Jul, 143, 7, 859-868
- Myeloid Sarcoma: Presenting with Massive Cervical and Inguinal Lymphadenopathy., Walsh JC, Arnold MG, Mohtashamian A., Head Neck Pathol, 2017, Jun, 11, 2, 219-223
- Myeloid neoplasm with t(3;8)(q26;q24): report of six cases and review of the literature., Xu X, Su M, Levy NB, Mohtashamian A, Monaghan S, Kaur P, Zaremba C, Garcia R, Broome HE, Dell'Aquila ML, Wang HY., Leuk Lymphoma, 2014, Nov, 55, 11, 2532-7
- Textbook and Online Atlas of Hematology for Medical Students and Residents., Rashidi, et al., 2013, Contributor
- Charcot-Leyden crystals associated with acute myeloid leukemia: case report and literature review., Khrizman P, Altman JK, Mohtashamian A, Peterson L, Chen YH, Tallman MS., Leuk Res, 2010, Dec, 34, 12, e336-8
Abstracts
- Defining low-HER2 cancers using RNA quantification by next generation sequencing (ASCO 24)., Andrew Ip, Maher Albitar, Hong Zhang, Ahmad Charifa, Sally Agersborg, Arash Mohtashamian, Deena Mary Atieh Graham, Donna M. McNamara, Stanley E. Waintraub, Martin Gutierrez, Andrew L. Pecora, and Andre Goy., Genomic Testing Cooperative and John Theurer Cancer Center, Hackensack Meridian Health.
- Multiple Alternative Splicing of HER2 transcripts and Exon Skipping with Potential Consequences on Function and Antibody-Based Therapy (ASCO 24)., Maher Albitar, Hong Zhang, Ahmad Charifa, Andrew IP, Sally Agersborg, Arash Mohtashamian, Deena Graham, Donna McNamara, Stanley Waintraub, Martin Gutierrez, Andrew Pecora, Andre Goy., Genomic Testing Cooperative and John Theurer Cancer Center, Hackensack Meridian Health.
- Using Cell-Free RNA in Monitoring Immune System and the Demonstration of Significant Systemic Deficiency in Lymphoid and Myeloid Biomarkers in Patients with Cancer (ASCO 24)., Maher Albitar, Hong Zhang, Ahmad Charifa, Andrew IP, Sally Agersborg, Arash Mohtashamian, David Siegel, Stanley Waintraub, Martin Gutierrez, Andrew Pecora, Andre Goy., Genomic Testing Cooperative and John Theurer Cancer Center, Hackensack Meridian Health.
- Using next generation sequencing of flow cytometry cd markers and machine learning as a replacement to flow cytometry analysis for the diagnosis of hematologic neoplasms (ASH 23)., Maher Albitar, Hong Zhang, Andrew Ip, Wanlong Ma, Lori Leslie, Tatyana Feldman, Jeffrey Estella, Ahmad Charifa, Arash Mohtashamian, Andrew Pecora, and Andre Goy., Genomic Testing Cooperative, LCA, Irvine, CA 92618, USA.
- Lymphoma diagnosis and classification using next generation sequencing of 30 cd markers and machine learning as an alternative to immunohistochemistry (ASH 23)., Maher Albitar, Hong Zhang, Andrew Ip, Wanlong Ma, James McCloskey, Kathrine Lender, Jeffrey Estella, Jamie Koprivnikar, Noa Biran, David Siegel, Ahmad Charifa, Arash Mohtashamian, Andrew Pecora, and Andre Goy., Genomic Testing Cooperative, LCA, Irvine, CA 92618, USA.
- Distinguishing Between Cancer-Related Mutations and Clonal Hematopoiesis Using Cell-Free RNA (cfRNA) Expression Levels in Machine Learning Model (ASCO 23)., Maher Albitar, MD; Hong Zhang, PhD; Andrew Ip, MD; Jeffrey Estella, BSc; Ahmad Charifa, MD; Wanlong Ma, BSc; Arash Mohtashamian, MD; Martin Gutierrez MD; Andrew Pecora, MD and Andre Goy MD., Genomic Testing Cooperative, Irvine, CA, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ.
- Defining the Immune Microenvironment in Myelodysplastic Syndrome and Acute Myeloid Leukemia Using Machine Learning., Maher Albitar, MD; Hong Zhang, PhD; Jamie Koprivnikar, MD; James McCloskey, MD; Katherine Linder, MD; Andrew Ip, MD; Jeffrey Estella, BSc; Ahmad Charifa, MD; Wanlong Ma, BSc; Arash Mohtashamian, MD; Andrew Pecora, MD and Andre Goy MD., Genomic Testing Cooperative, Irvine, CA, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ, ASCO 2023.
- Using Machine Learning to Characterize Lung Cancer Microenvironment and the Development of a Model to Predict the Presence of Similar Microenvironment in Other Cancers., Ahmad Charifa, MD; Hong Zhang, PhD; Andrew Ip, MD; Jeffrey Estella, BSc; Wanlong Ma, BSc; Arash Mohtashamian, MD; Martin E Gutierrez, MD; Andrew Pecora, MD; Andre Goy MD and Maher Albitar, MD., Genomic Testing Cooperative, Irvine, CA, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ, ASCO 2023.
Timeline
Staff Pathologist / Hematopathologist
Renown Regional Medical Center
03.2024 - Current
Director of Hematology
Genomic Testing Cooperative (GTC)
04.2023 - 03.2024
Contract/part time surgical pathologist
Pacific Rim Pathology (Sharp Healthcare)
07.2021 - 08.2022
Director of Clinical Support Services & Staff Pathologist, USN (Ret. CAPT/0-6 May 2023)
US Navy, Naval Hospital, Camp Pendleton
05.2018 - 04.2023
Navy Pathology Specialty Leader and Naval Medical Center, San Diego residency program director
US Navy, Naval Medical Center, San Diego
12.2015 - 05.2022
Contract/part time hematopathologist
Quest Diagnostics
07.2011 - 07.2022
Department head and staff pathologist
US Navy, Okinawa, Japan
07.2007 - 06.2009
General Medical Officer (GMO)
US Navy, 7th Marines, 29 Palms, California
07.2001 - 07.2003
Fellowship - Hematopathology
Northwestern University Feinberg School of Medicine
Residency - Anatomic and Clinical Pathology
Walter Reed National Military Medical Center
Internship - Internal Medicine
National Naval Medical Center
Doctor of Medicine (MD) -
The Medical College of Wisconsin
Dual Degrees - Biological Sciences/Biophysics and Philosophy
University of California, Irvine (UCI)