Summary
Overview
Work History
Education
Skills
Timeline
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Brian Sze

Milpitas,CA

Summary

Current M.S. candidate in Bioengineering seeking internship opportunities in immunotherapy and preclinical research. Bringing over 3 years of industrial experience with a proven track record in protein expression and purification. A highly motivated researcher with a strong foundation in immunology, demonstrating adeptness in time management and critical thinking.

Overview

7
7
years of professional experience

Work History

BioAssay Co-op

Sanofi US
07.2025 - Current
  • Collaborated with a Scientist to develop and qualify ELISA-based impurity assays for host cell protein (HCP) detection using both commercial kits and proprietary product-specific assays.
  • Executed simple and complex experiments with appropriate controls, under guidance from a supervisor; assisted in planning and prioritizing daily workflows.
  • Analyzed and interpreted experimental data; compiled results for internal review.
  • Contributed to maintenance of a GMP-compliant laboratory environment.
  • Drafted technical reports with clear data presentation; supported internal presentations on technical findings

Research Associate

Abcam
10.2021 - 12.2022
  • Coordinate with interdisciplinary Boston R&D teams to integrate protein purification protocols and systems
  • Troubleshoot and establish new protocols for 10 proteins with either low solubility, yield, or activity
  • Ensure proteins meet quality standards and established tolerances through QC testing
  • Perform recombinant protein purification from E. Coli expression system
  • Collaborate with fermentation team to complete liter scale E. Coli fermentation
  • Perform data entry, proper documentation, and protein transfer to shipping and logistics team to meet demanding weekly backorder goals

Research Associate I/II

Biovision Inc.
08.2019 - 10.2021
  • Maintained mammalian cell culture (HEK293/CHO) for transfections and stable cell line generation
  • Collaborated with Lead Senior Scientist to co-develop over 30 new protein targets as standalone products and in assay kits
  • Developed recombinant antibody pair for novel HCV Antigen ELISA
  • Produced several COVID-19 targets including Spike and ACE2 proteins
  • Established in-house cloning system with team lead to develop plasmids for new protein targets
  • Presented data to R&D team in bi-weekly meetings
  • Managed several laboratory resources including liquid nitrogen and carbon dioxide tanks

Intern

Biovision Inc.
06.2018 - 09.2018
  • Performed recombinant protein purification from mammalian expressed cells
  • Analyzed proteins with SDS PAGE and determined activity with enzymatic assays
  • Completed DNA amplification and purification for new plasmids

Education

Master of Science - Bioengineering

Santa Clara University
Santa Clara, CA
06-2026

Bachelor of Science - Bioengineering

University of California, Riverside
Riverside, CA
08.2019

Skills

  • Mammalian/Insect/E Coli protein expression system
  • Affinity chromatography (Ni-NTA, Protein G/A, Heparin)
  • Size exclusion chromatography
  • HPLC/FPLC
  • PCR (polymerase chain reaction)
  • Molecular Cloning
  • DNA amplification and purification
  • DNA/protein gel electrophoresis
  • UV-Vis Spectroscopy
  • Western Blot, ELISA immunoassays

Timeline

BioAssay Co-op

Sanofi US
07.2025 - Current

Research Associate

Abcam
10.2021 - 12.2022

Research Associate I/II

Biovision Inc.
08.2019 - 10.2021

Intern

Biovision Inc.
06.2018 - 09.2018

Master of Science - Bioengineering

Santa Clara University

Bachelor of Science - Bioengineering

University of California, Riverside

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