Canglin Yao
Brooklyn,NY
Overview
3
3
years of professional experience
Work History
Project on Biotechnology & Pharmaceutical Industry
New York University, Tandon School of Engineering
02.2024 - 05.2024
- Supervised by Professor Evgeny Vulfson from Chemical and Biomolecular Engineering Department, NYU Tandon School of Engineering.
- Project Title: Hypothetical Design of Orally Administered Drug to Elevate Serum Iron Level in Iron-Refractory Iron Deficiency Anemia (IRIDA).
- Project report collects research on pathogenesis, current treatments, and treatment markets of IRIDA, designs new hypothetical drug molecule based on structural analysis, and formulated schemes of experiments needed for new drug application.
Research Intern
Cracan Lab Of Scintillon Institute
03.2022 - 06.2023
- Supervised by Professor Valentin Cracan from Scintillon Institute and Scripps Research.
- Conducted research on NAD(P)H/NAD(P)+ redox enzymes.
- Independently and routinely performed molecular cloning and protein expression in E. coli, protein purification by Fast Protein Liquid Chromatography (FPLC), enzyme kinetics studies by UV-Vis spectroscopy, and cell culture maintenance.
Research Intern
State Key Laboratory Of Cellular Stress Biology
03.2021 - 09.2021
- Supervised by Professor Liang Liu and Professor Jiyun Chen from School of Life Sciences, Xiamen University, China.
- Assisted structural biology researches on DNA/ RNA methyltransferases and conducted individual research project.
- Performed molecular cloning, protein expression in E. coli, protein purification, and protein crystallization.
Online Training and Remote Research Seminar
University Of South California
06.2021 - 09.2021
- Topic of study: Introduction to Epidemiology
- Instructed by Professor Roksana Karim from University of Southern California.
- Studied introductory methods of epidemiological research and statistic software (SPSS statistics and Excel). Performed group presentation and completed conference review paper discussing association between sleep and obesity, co-authored with 2 peer students.
Online Training Program of Molecular Biology
Chinese Academy of Sciences
01.2021 - 04.2021
- Instructed by Dr. Jian Song from Chinese Academy of Sciences
- Studied laboratory techniques like PCR, gel electrophoresis, ELISA, transformations, protein purifications, etc. Studied bioinformatics tools: NEBuilder, SnapGene, and Benchling.
Education
Master of Science - Biotechnology
New York University
05.2025
Bachelor of Science - Molecular And Cell Biology
University of California - San Diego
06.2023
Publications
Pan, X., Heacock, M. L., Abdulaziz, E. N., Violante, S., Zuckerman, A. L., Shrestha, N., Yao, C., Goodman, R. P., Cross, J. R., & Cracan, V. (2024). A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells. Nature chemical biology, 20(5), 594–604. https://doi.org/10.1038/s41589-023-01460-w
Chen, J., Hu, R., Chen, Y., Lin, X., Xiang, W., Chen, H., Yao, C., & Liu, L. (2022). Structural basis for MTA1c-mediated DNA N6-adenine methylation. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31060-6
Award
Gold Award in the Twenty Third British Biology Olympiad Competition 2018
Silver Award in the ASDAN China-US Local Chemistry Olympiad Competition China Section 2018
Silver Award (National Ranking) in the 2018 BioOlympiad Initiative USA-China
Timeline
Project on Biotechnology & Pharmaceutical Industry
New York University, Tandon School of Engineering
02.2024 - 05.2024
Research Intern
Cracan Lab Of Scintillon Institute
03.2022 - 06.2023
Online Training and Remote Research Seminar
University Of South California
06.2021 - 09.2021
Research Intern
State Key Laboratory Of Cellular Stress Biology
03.2021 - 09.2021
Online Training Program of Molecular Biology
Chinese Academy of Sciences
01.2021 - 04.2021
Master of Science - Biotechnology
New York University
Bachelor of Science - Molecular And Cell Biology
University of California - San Diego
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