Deborah Wong
Summary
Technical expertise in laboratory settings began with clinical diagnostics and evolved into advanced research in engineered gene therapy, leveraging cutting-edge technology. Significant cross-functional contributions advanced a biotech startup from discovery to clinical phases, paving the way for gene therapy's potential in the CNS. Passionate about improving operational efficiency through collaboration to ultimately advance patient impact through data-driven decision making.
Overview
7
7
years of professional experience
Work History
Senior Research Associate
Capsida Biotherapeutics
01.2022 - Current
- Optimized and developed RNA quality projects by implementing viral-like particle internal controls, improving methods for extraction of difficult fibrous and ocular tissues, and introducing scRNA-seq experiments.
- Developed and qualified HPLC quantitation QC assays to ensure IND-readiness of AAV drug products, improving regulatory compliance and data reproducibility.
- High-throughput research screening using DNA and RNA extractions, NGS, and qPCR biodistribution to identify AAV capsids successful of crossing the blood brain barrier to deliver therapeutic cargo.
- Exploratory experiments identifying receptor-binding interactions utilizing ELISA and flow cytometry.
- Heavily utilized process automation with ELN, analysis pipelines, and liquid handling robotics to increase high-throughput capacity and decrease turnaround time of data delivery.
Laboratory Technician
Tetracore/Cirrus Dx
01.2020 - 01.2022
- Lead deployment of RT-PCR Sars-CoV-2 testing as part of a mobile lab operation managing high-pressure situations across the US.
- Optimized workflows to best suit client needs and identify more streamlined methods for communication, reporting, and troubleshooting.
- Research and development of pilot chaotic PCR assay experiments for short turnaround testing of Sars-CoV-2.
Laboratory Analyst
Suretox Laboratory (now Biogenica)
01.2019 - 01.2020
- Conducted analytical development and validations for respiratory pathogens, antibiotic resistant microbiota, and pharmacogenetic testing according to CLIA, NY, and NJ state regulations.
- Extracted and prepared libraries for cancer gene screening using Illumina NGS methods on Miniseqs.
- Performed clinical toxicology sample preparation, maintenance, optimization, data analysis, and data reporting within a 24-48 turnaround period.
Education
Bachelor of Science - Health Science
Boston University
Boston, MA01-2019
Skills
- QC Assay Development & Qualification
- Clinical Assay Validation
- Process Automation
- Experimental Design
- Protocol Writing
- Project Management
- Lab Management
- Lab Training
- Clinical Accessioning
- MS Excel & Office
Timeline
Senior Research Associate
Capsida Biotherapeutics
01.2022 - Current
Laboratory Technician
Tetracore/Cirrus Dx
01.2020 - 01.2022
Laboratory Analyst
Suretox Laboratory (now Biogenica)
01.2019 - 01.2020
Bachelor of Science - Health Science
Boston University
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