Elizabeth Amelotte

I am a curious and collaborative person who enjoys the learning opportunities research provides. I have a strong foundation in colony management. I am hoping to join a lab where I can utilize my existing skill set and continue building on other techniques.

• Nicole J. Ferland Undergraduate Summer Research Award (2023)
• North American Vascular Biology Organization Travel Award (2023)
• All-American All-Academic ICSA (2022-2023)
• All-American All-Academic ICSA (2023-2024)

1) R. Carley & C. Lee, J. M. Berus, C. S. Mantsounga, J. C. Neverson, S. Sharma, O. Caballero,
C. Parry, J. Pierce, E. Amelotte, C. Butler, A. Healy, H. Alemara, C.l. Williams, R.M. Olson, F.
Sellke, G. Choudhary, A. R. Morrison, “Nuclear localization of NF-κB by Rac1 determines IL-
1β Signaling-dependent Atherosclerotic Calcification.” In revision, Journal of Clinical
Investigation (JCI), March 6, 2024.
2) Lee C, Khan R, Mantsounga CS, Sharma S, Pierce J, Amelotte E, Butler CA, Farinha A,
Parry C, Caballero O, Morrison JA, Uppuluri S, Whyte JJ, Kennedy JL, Zhang X, Choudhary
G, Olson RM, Morrison AR. IL-1β-driven NF-κB transcription of ACE2 as a Mechanism of
Macrophage Infection by SARS-CoV-2. bioRxiv [Preprint]. 2025 Feb Submission. 2025.
3) Sharma S, Pierce J, Neverson JC, Khan R, Lee CF, Uppuluri S, Parry C, Amelotte E, Butler
CA, Sellke FW, Harrington EO, Choudhary G, Morrison AR, Mantsounga CS, “Macrophage
proangiogenic VEGF-A is required for inflammatory arteriogenesis during vascular injury.”
Biomedicines, In Submission. 2025.
4) C.Mantsounga, J. Pierce, M. Clark, O. Caballero, A. Farinha, S. Sharma, S. Uppuluri, J. Neverson, , C. Lee, E. Amelotte, C. Butler, F. Sellke, A. Fedulov, G. Choudhary, G. Lisi, A.R. Morrison, “Aging Impairs Inflammatory Arteriogenesis by Disruption of VEGF-A mRNA Stability Conferred by Dicer1 Dose-sensitive
miR-29” In Preparation.

1. R. Carley, C. Lee, C. Mantsounga, S. Sharma, J. Neverson, J. Pierce, E. Amelotte*, C. Butler,
G. Choudhary, A.R. Morrison “Immune mediated mechanisms of macrophage Rac1-IL-1β
signaling leading to atherosclerotic calcification.” Vasculata. July 18-21, 2022. Poster # 1177-
000120. *Presenter
2. S. Sharma, C. Mantsounga, J. Neverson, C. Lee, J. Pierce, E. Amelotte, R. Carley, C. Butler,
G. Choudhary, A.R. Morrison. “Macrophage IL-1B Drives Angiogenesis During Wound Healing.”
NAVBO Vasculata 2022, July 19, 2022. Abstract #1177-000117, Poster #T03
3. C. Lee, R. Carley, J. Berus, C. Mantsounga, S. Sharma, J. Neverson, E. Amelotte, J. Pierce,
C. Butler, G. Choudhary, R. Olson, A.R. Morrison. “Macrophage Rac1-NF-kB-IL-1β
Atherosclerotic Signaling in a Novel Humanized ACE2 Mouse Model of SARS-CoV-2 Infection.”
28th Annual Golden Stethoscope Awards, September 8, 2022. (Lee, Oral presentation, GSA
finalist and winner)
4. S. Sharma, C. Mantsounga, C. Lee, J. Neverson, J. Pierce, E. Amelotte, R. Carley, C. Butler,
G. Choudhary, A.R. Morrison. “Macrophage IL-1B-VEGF-A Signaling Axis Drives Angiogenesis
During Wound Healing.” IVBM 2022, October 15, 2022. Prog# 2072, Abstract #1177-000570,
Poster #72
5. C. Lee, R. Carley, J. Berus, C. Mantsounga, S. Sharma, J. Neverson, E. Amelotte, J. Pierce,
C. Butler, G. Choudhary, A.R. Morrison. “Macrophage Rac1-NF-κB-IL-1β Atherosclerotic
Signaling Axis Upstream of ACE2 Expression and SARS-CoV-2 Virulence.” IVBM 2022, San
Francisco. October 15, 2022. Program Number 2037, Poster #37. (Lee, Oral presentation,
NAVBO InFocus session, August 24, 2023)
6. R. Carley, C. Lee, C. Mantsounga, J. Berus, S. Sharma, J. Pierce, C. Parry, E. Amelotte, C.
Butler, G. Choudhary, A.R. Morrison. “A Rac1‐NF‐kB transcriptional axis regulates IL‐1β during
atherosclerotic calcification” NAVBO Vascular Biology 2023, October 18, 2023. Abstract #97
Poster W-01.
7. S. Sharma, C. Lee, J. Neverson, J. Pierce, E. Amelotte, R. Carley, C. Butler, E. Pineda, C.
Parry, R. Mendez, O. Caballero, G. Choudhary, C. Mantsounga, A.R. Morrison. “Macrophage IL-
1B Driven Angiogenesis in Wound Healing.” NISBRE 2022, December 13, 2022. Abstract, Poster
#49
8. S. Sharma, C. Mantsounga, C. Lee, J. Neverson, J. Pierce, E. Amelotte, R. Carley, C. Butler,
G. Choudhary, A.R. Morrison. “Impaired Macrophage IL-1beta-Dependent Wound Healing in the
Context of Diabetes” AHA Vascular Discovery: From Genes to Medicine 2023 Scientific Sessions,
May 10-13, 2023. Abstract #661.
9. R. Carley, C. Lee, J. Berus, C. Mantsounga, S. Sharma, O. Caballero, C. Parry, E. Pineda, J.
Pierce, E. Amelotte, C. Butler, G. Choudhary, A.R. Morrison. “Macrophage Rac1 as a
transcriptional co-factor for NF-kB-driven IL-1β expression and consequent atherosclerotic
calcification”. AHA Vascular Discovery: From Genes to Medicine 2023 Scientific Sessions, May
10-13, 2023. Poster #642.
10. R. Carley, C. Lee, C. Mantsounga, S. Sharma, O. Caballero, C. Parry, J. Pierce, E. Amelotte,
C. Butler, G. Choudhary, A.R. Morrison. “Rac1 and NF-kB Signaling Regulate Macrophage
Expression of IL-1β and Atherosclerotic Calcification: Implications for Targeted Therapies. Gordan
Research Seminar: Atherosclerosis, June 17, 2023. Poster M-08. (Carley, Oral presentation,
NAVBO Travel Award)
11. C. Lee, C. Mantsounga, S. Sharma, R. Carley, E. Amelotte, J. Pierce, C. Butler, G.
Choudhary, R. Olson, A.R. Morrison. “A Novel Humanized ACE2 Mouse Model for Evaluating
COVID-19 Infection in Cardiovascular Disease.” AHA Vascular Discovery: From Genes to
Medicine 2023 Scientific Sessions, May 10-13, 2023. Poster #640. ATVB, October 2023, Abstract
#262. doi: 10.1161/atvb.43.suppl_1.262
(https://www.ahajournals.org/doi/10.1161/atvb.43.suppl_1.262)
12. C. Lee, R. Carley, S. Sharma, J. Pierce, E. Amelotte, C. Butler, C. Mantsounga, G.
Choudhary, R. Olson, A.R. Morrison. “Validation of a Novel Humanized ACE2 Mouse Model of
SARS-CoV-2 Infection for Evaluating COVID-19 and Cardiovascular Comorbidities.” 30th Annual
Golden Stethoscope Awards, IAMA, September 22, 2023. (Lee, Oral presentation, Golden
Stethoscope Award finalist and winner).
13. C. Mantsounga, O. Caballero, C. Lee, S. Sharma, J. Pierce, C. Parry, E. Amelotte, R. Carley,
C. Butler, G. Choudhary, A.R. Morrison. “Age-related increases in DNA methylation impair HuR-
mediated VEGF-A mRNA stability and consequent inflammatory arteriogenesis.” Vascular Biology
2023, October 15-18, 2023. Abstract #237.
14. C. Lee, R. Carley, J. Berus, E. Amelotte*, S. Sharma, J. Pierce, C.S. Mantsounga, C. Butler,
A.R. Morrison. “Atherosclerotic Calcification Requires Macrophage IL-1β Expression” NAVBO
Vascular Biology 2023, October 15-19, 2023. Abstract #124. (Amelotte, Oral presentation,
NAVBO Travel Award) *Presenter
16. C.S. Mantsounga, J. Pierce, M. Clark, O. Caballero, A. Farinha, S. Sharma, J. Neverson, C.
Lee, E. Amelotte, C. Butler, F. Sellke, A. Fedulov, G. Choudhary, G. Lisi, A.R. Morrison.
"Targeting Age-related Mechanisms that Impair Arteriogenesis to Improve Blood Flow after Injury."
Vascular Biology 2024, October 20-24, 2024. Abstract #261.
17. E. Amelotte*, C. Mantsounga, O. Caballero, J. Pierce, A. Farinha, S. Uppuluri, C. Butler, G.
Choudhary, A. R. Morrison, “Progression of Spontaneous Aortic Valve Stenosis in Aging New
Zealand Obese Mice” PVAMC Research Week, May 15, 2025. *Presenter