Eugene Yeboah

Global and Public Health Portfolio

• Southeast Asia Regional Training, 2023-present
• Collaborate with Ministry's of Health, CDC, and Chan Zuckerberg initiative to organize genomic epidemiology courses for laboratorians and epidemiologists in Indonesia, Philippines, Thailand, Cambodia and Vietnam so that genomic data can be translated to inform public health decision
• Thailand (National Institute of Health) 2022-present
  Work with the National Institute of Health to address ongoing outbreak investigations of unknown etiology through next generation sequencing of bacteria and viruses
• Jordan (Ministry of Public Health) 2022 - present
  Work with the Central Public Health lab of Jordan and the Jordanian Ministry of Health epidemiology team to develop a framework for contact tracing using genomic epidemiology and phylogenetic tools
• Provide in-person training on detecting pathogens of concern and disease outbreaks in Amman, Jordan
• India (india CDC and All India Institute of Medical Sciences, Ministry of Health) 2022-Present
• Work with CDC India to develop policies and strategies for pandemic preparedness by providing guidance on capacity building through setting up multiple provincial laboratories
  Support laboratories in India working on tuberculosis, acute fibril illness, and general viral surveillance
• Ghana (KNUST, NHPRL and Noguchi) 2022 - present
• Provide online bioinformatics and genomic epidemiology training to National Public Health laboratory scientists in Ghana to support disease surveillance and outbreak investigations
• Provide hands-on, in-person training on next generation sequencing techniques, quality management systems and data analysis, for pandemic preparedness
• Kenya (Kenya Medical Research Institute, Ministry of Health) 2021 - present
• Develop policies and guidelines for the Ministry of Health and the Kenya Medical Research Institute on viral and bacterial disease testing
• Support the National Public Health laboratory and the Kenya Medical Research Institute in Nairobi and Kisumu to build laboratory capacity and track disease progression in the region
• Mozambique (Mozambique National Institute of Health) 2021 - present
• Develop national HIV drug resistance sequencing protocol and provide guidance to Ministry of Health in revising the country's HIV treatment guidelines
• Support Mozambique Institute of National Health in Maputo to monitor the emergence and estimate the prevalence of acquired HIV drug resistance among individuals receiving treatment
• Oman (Ministry of Public Health) 2021 - present
• Work in collaboration with CDC to provide epidemiology training to the Oman Central Public Health laboratory staff on pandemic preparedness and surveillance for diseases such as TB, HIV, Measles, and Sepsis
• Train the national public health laboratory staff on quality control and quality assurance best practices
• General Job Duties
• Serve as APHL staff lead for GHSA (a global effort to strengthen the world's ability to prevent, detect, and respond to infectious disease threats ) and PEPFAR (The United States President's Emergency Plan for AIDS Relief through expanding access to HIV prevention, treatment, and care interventions in more than 50 countries around the world)
• Collaborate with ministry of health staff in country and provide consultation to the funding source, country laboratory staff, APHL country teams, other partner organizations, and international agencies such as the World Health Organization (WHO) and Center for Disease Control and Prevention (CDC) on Next Generation Sequencing activities
• Hire and manage APHL consultants, develop scope of work, and implement work plans in-country
• Strengthen laboratory systems in over 10 countries in Asia, Africa and Middle East Regions by leading development of and training in laboratory design/set up, best practices, and quality management systems
• Coordinate APHL member participation in Global Health projects related to laboratory strengthening and NGS capacity building
  Develop original global training resources and writings for APHL publications
• Represent Global Health Program at meetings and conferences and present on funded activities
• Work with legal department to manage RFP bids and vendor contracts
• Develop country work plans and budgets for APHL programs
• Lead communication efforts and administrative and financial reporting requirements for assigned programmatic activities
• Develop budget and forecast documents for funding opportunities and spending monitoring.

• Collaborated with APHL, CDC, infectious control officers, state epidemiologists, and health care providers on genetic sequencing needs, infections disease control strategies, and protocol updates.
• Developed, implemented, and validated sequencing of SARS-CoV-2 panels to meet both CLIA and CAP guidelines for Oregon State Public Health Laboratory.
• Designed procedure for recording, analysis, and distribution of statistical information in all lab areas to meet accreditation standards by CLIA, CAP and OR-OSHA.
• Utilized understanding of wet-lab technology including DNA library preparation and sequencer technology to complete viral sequencing and analysis pipelines.
• Assisted bioinformatics pipeline developments and automated special projects using R Programming in support of sequencing analysis and reporting.
• Developed and tested new protocols for COVID-19 sequencing products to find high quality, low cost options.
• Trained microbiologists to perform sequencing experiments and analyze results using torrent plugins from Thermo Fisher Scientific.
• Managed and archived quality documentation and conducted internal and external quality audits.
• Optimized business and management practices to improve all facets of project development and execution.
• Led key projects while managing timelines and meeting deadlines within budgetary limits.
• Developing and established technical procedures, method evaluations plans, and performance summary reports that met CLIA/CAP regulatory requirements.
• Fostered relationships with vendors to promote positive working relationships.
• Reined in project costs while meeting key milestones.
• Managed OSPHL's sequencing database and supported ELR reporting requirements.
• Used advanced clinical diagnostic platforms, such as high throughput sequencing instruments, automated library preparation systems for SARS-CoV-2 sequencing.
• Collaborated with laboratory partners to develop work-flows for Illumina, Oxford Nanopores, and ThermoFisher sequencing instruments.
• Assisted informaticians in using scripts written in Python and R, Linux environments, bioinformatics computing toolkits and cloud computing environments like Minknow and Terra as well as Docker container.
• Utilized microsoft and Linux workspaces to run computer servers, file transfer protocol (NFS, FTP and sFTP), Virtual Private Network (VPN), Virtual Torrent Servers and Microsoft Office including MS Access, PowerPoint, Word, Teams, Outlook and Excel.
• Developed, updated and enhanced databases used for storage and retrieval of bioinformatics data.
• Developed and implemented performance improvement strategies and plans to promote continuous improvement of OSPHL's testing needs.
• Worked with R Studio to build data queries and produce analytical reports to streamline sequencing workflows for GISAID and NCBI.

• Prepared media and assembled COVID-19 collection kits to be distributed to local health partners.
• Prepared biological specimens for testing, analysis and screening.
• Verified and documented shipments, courier manifests and received COVID-19 test kits from testing labs.
• Receive and accessioned samples/specimens into Oregon State Public Health Laboratory LIMS systems including Category Category B infectious substances.
• Disposed off hazardous waste through autoclaving and waste management systems.
• Maintained consumables and inventory by receiving and inventoried incoming shipments, tracking, courier facilitation, shipments and reordered before supplies diminished.
• Documented information by maintaining daily logs and equipment record books.
• Trained new associates in laboratory procedures and standards.
• Supported laboratory staff with advanced troubleshooting, resolving complex problems and helping with special projects.

• Investigated, compiled and modeled information for detailed project proposals to set up and design high-throughput molecular diagnostic laboratory for pre-implantation genetics.
• Conferred with scientists, engineers and regulators to set up whole genome sequencing laboratory for human embryos.
• Managed day to day activities of lab and provided both assistance and education to referring centers and physicians about whole genome sequencing results.
• Assisted with development and administration of laboratory budgets, infectious substance shipment and waste management.
• Directed quality assurance standards to maximize results while meeting regulatory standards.
• Analyzed sequenced data using Thermofisher browsers and bioinformatics plugins for Prenatal Genomic Diagnosis of human embryos.
• Interacted well with physicians, field agents and customers to build connections and nurture relationships.
• Managed day to day activities of lab and provided both assistance and supervision to students performing research for projects

• Developed and Optimized whole genome sequencing tests, protocols and technologies for Illumina Miseq and ThermoFisher sequencing platforms.
• Managed entire operations at Portland Oregon lab and oversaw all lab procedures.
• Ensured on day-to-day basis that all quality control and assurance measures were met and up to date.
• Worked with physicians, scientists, researchers and bioinformaticians to develop new tools for prenatal genetic disorders.
• Developed and analyzed quality control processes and deliverables to determine present standards and establish recommended action plans.
• Evaluated collected data points from research experiments to produce summary reports for disease prevention and research publications.
• Helped scientific and engineering teams improve sequencing algorithms for data analysis tools by conducting validations on new diagnostic protocol.
• Managed clinical operations to assure timely release of test results to referring physicians, clients and centers.
• Developed new techniques, protocols and validations in molecular biology, applied genomics and bioinformatics to process, analyze and diagnose prenatal genetic disorders.
• Effectively and efficiently processed 480 clinical and research samples weekly using Array Comparative Genomic Hybridization, Ion Torrent PGM sequencing from Thermo Scientific and processing protocols from Illumina Miseq sequencing platforms.
• Analyzed and interpreted results of sequenced genetic data using ion torrent and Illumina-Bluefuse platforms.
• Participated in research panels and presented research publication in conferences, scientific boards and annual reproductive conference meetings country-wide.

• Inspected preparation and storage equipment regularly to assess and maintain performance for cost-effective, safe operations.
• Adjusted job assignments and schedules to keep pace with dynamic business needs, factoring in processes, employee knowledge and customer demands.
• Coordinated with event planners for floor and table layouts, guest numbers and overall catering needs.
• Set schedules for 70 staff by planning and designating shifts and hours.
• Cross-trained existing employees to maximize team agility and performance.
• Evaluated suppliers by assessing quality, timeliness and compliance of deliveries to maintain tight cost controls and maximize business operational efficiency.
• Oversaw day-to-day processing of payroll for 70 employees, including review of timesheets and computing pay in accordance with FLSA.
• Prepared project budgets, forecasting and inventory, and material pricing points.
• Determined required job seeker qualifications for potential interview by reviewing and evaluating resume and application information.
• Oriented newly hired employees by providing company information, facilitating on-boarding processes and establishing position-related requirements.
• Maintained work structure by updating job requirements and job descriptions for all positions.
• Maximized team knowledge and productivity by effectively training, monitoring and directing employees in application of best practices and regulatory protocols.
• Worked with marketing department to create targeted advertising strategies for key customer demographics.