Fernando Pereira Beserra

Experienced biomedical scientist with 10+ years of expertise in pharmacology, biotechnology, and experimental therapeutics. Proven track record in molecular biology, cell-based assays, and preclinical wound healing models. Strong background in product development, nanotechnology-based formulations, and translational research. Interested in scientific expertise in pharmaceutical, biotech or clinical diagnostics environments.

• Positions and Scientific Appointments
• 2024-present Postdoctoral Research, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
• 2023-2024 Visiting Research, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
• 2019-2020 Retail Pharmacist at Raia Drogasil, Botucatu, SO, Brazil.
• 2014 - 2015 Professor of Pharmacology, Faculdade Marechal Rondon (FMR).

• Undergraduate students
• 1. Marcos Vital de Sa Ferreira. Evaluation of the healing potential of a nanoemulsion containing green propolis extract in the treatment of wounds in hyperglycemic rats infected with methicillin-resistant Staphylococcus aureus. 2022. (bachelor’s degree in biomedical sciences) - São Paulo State University (UNESP), Research Support Foundation of the State of São Paulo.
• 2. Mariana Conceicao. Characterization of the activity of fibroblasts and endothelial cells in the healing of cutaneous wounds in rats topically treated with Brazilian red propolis. 2021. (bachelor’s degree in biomedical sciences) - São Paulo State University (UNESP), Research Support Foundation of the State of São Paulo.
• 3. Marina Naomi Miyashita. Development of solid lipid nanoparticles containing brown propolis for topical application in rat wounds. 2019. (bachelor’s degree in Biological Sciences) - São Paulo State University (UNESP).
• 4. Raphaella Gomes Bergstrom. Evaluation of the healing effect of solid lipid nanoparticles containing red propolis in experimentally induced skin wounds in rats. 2019. (bachelor’s degree in biomedical sciences) - São Paulo State University (UNESP).
• 5. Patricia Luisa Bergamo. Morphological aspects of cutaneous wound healing induced by topical treatment with Lupeol-based cream isolated from Bowdichia virgilioides Kunth (Sucupira-preta). 2014 (bachelor’s degree in medical physics) - São Paulo State University (UNESP).
• 6. Danilo Augusto Bergamo. Evaluation of the antioxidant and anti-inflammatory effect of lupeol-based cream isolated from Bowdichia virgilioides Kunth (Sucupira-preta) on the healing process of cutaneous wounds. 2014. (bachelor’s degree in medical physics) - São Paulo State University (UNESP), Research Support Foundation of the State of São Paulo.

• 1. Conceição M, Di Filippo LD, Duarte JL, Beserra FP, Gremião MPD, Chorilli M. Repurposing doxycycline for Alzheimer's treatment: Challenges from a nano-based drug delivery perspective. Brain Behav Immun Health. 2024 Oct 25;42:100894. doi: 10.1016/j.bbih.2024.100894. PMID: 39525305; PMCID: PMC11550769.
• 2. Conceição, Mariana; Beserra, Fernando Pereira; Aldana Mejia, Jennyfer Andrea; Caldas, Gabriel Rocha; Tanimoto, Matheus Hikaru; Luzenti, Andréia Marincek; Gaspari, Priscyla Daniely Marcato; Evans, Nicholas David; Bastos, Jairo Kenupp; Pellizzon, Cláudia Helena. Guttiferones: An insight into occurrence, biosynthesis, and their broad spectrum of pharmacological activities. Chemico-Biological Interactions, v.370, p. 110313, 2023.
• 3. Gushiken, Lucas F. S.; Beserra, Fernando P.; Hussni, Maria F.; Gonzaga, Murilo T.; Ribeiro, Victor P.; De Souza, Patricia F.; Campos, Jacqueline C. L.; Massaro, Tais N. C.; Hussni, Carlos A.; Takahira, Regina K.; Marcato, Priscyla D.; Bastos, Jairo K.; Pellizzon, Cláudia H. Copaifera langsdorffii Oleoresin-Loaded Nanostructured Lipid Carrier Emulgel Improves Cutaneous Healing by Anti-Inflammatory and Re-Epithelialization Mechanisms. International Journal of Molecular Sciences, v. 24, p. 15882, 2023.
• 4. Conceição, Mariana; Gushiken, Lucas Fernando Sérgio; Beserra, Fernando Pereira; Aldana-Mejia, Jennyfer Andrea; Tanimoto, Matheus Hikaru; Ferreira, Marcos Vital De Sá; Alves, Andreia Cristina Miranda; Miyashita, Marina Naomi; Bastos, Jairo Kenupp; Beserra, Fernando Pereira; Pellizzon, Cláudia Helena. Histological, Immunohistochemical and Antioxidant Analysis of Skin Wound Healing Influenced by the Topical Application of Brazilian Red Propolis. Antioxidants, v.11, p. 2188, 2022.
• 5. Gushiken, Lucas Fernando Sérgio; Beserra, Fernando Pereira; Hussni, Maria Fernanda; Gonzaga, Murilo T.; Ribeiro, Victor Pena; De Souza, Patricia Fernanda; Campos, Jacqueline Costa Lima; Massaro, Taís Nader Chrysostomo; Hussni, Carlos Alberto; Takahira, Regina Kiomi; Marcato, Priscyla Daniely; Bastos, Jairo Kenupp; Pellizzon, Cláudia Helena. Beta-caryophyllene as an antioxidant, anti- inflammatory and re-epithelialization activities in a rat skin wound excision model. Oxidative Medicine and Cellular Longevity (Online), v. 2022, p. 1-21, 2022.
• 6. Beserra, Fernando P.; Marincek, Andréia; Rodrigues, Debora M.; Caldas, Gabriel R.; Ferreira, Iasmin R. S.; Silva, Letícia B.; Schneider, Ayda H.; Sá, Keyla S. G.; Gaspary, Priscyla D. M.; Bastos, Jairo K. Brazilian Green Propolis-Based Nanostructured System: Development, Characterization and its role in the Modulation of Cytokines in In Vitro and In Vivo Experimental Models. FASEB JOURNAL, v. 36, p. 1, 2022.
• 7. Piotrowska, Anna; Beserra, Fernando Pereira; Wierzbicka, Justyna Marta; Nowak, Joanna Irena; 'Mijewski, Micha' Aleksander. Vitamin D Enhances Anticancer Properties of Cediranib, a VEGFR Inhibitor, by Modulation of VEGFR2 Expression in Melanoma Cells. Frontiers in Oncology, v. 11, p.1, 2021.
• 8. SILVA, M. J. D.; BESERRA, F. P.; RODRIGUES, V. P.; SILVA, M. A.; SILVA, G. A.; HIRUMA-LIMA, C. A.; VILEGAS, W. Mimosa caesalpiniifolia (Fabaceae), a medicinal plant from Brazilian cerrado with antioxidant and antiinflammatory properties. International Journal of Complementary & Alternative Medicine, v. 4, p. 58-62, 2021.
• 9. Gushiken, Lucas Fernando Sérgio; Beserra, Fernando Pereira; Bastos, Jairo Kenupp; Jackson, Christopher John; Pellizzon, Cláudia Helena. Cutaneous Wound Healing: An Update from Physiopathology to Current Therapies. Life, v. 11, p. 665, 2021.
• 10. Rozza, Ariane Leite; Beserra, Fernando Pereira; Vieira, Ana Júlia; Oliveira De Souza, Eduardo; Hussni, Carlos Alberto; Martinez, Emanuel Ricardo Monteiro; Nóbrega, Rafael Henrique; Pellizzon, Cláudia Helena. The Use of Menthol in Skin Wound Healing-Anti-Inflammatory Potential, Antioxidant Defense System Stimulation and Increased Epithelialization. Pharmaceutics, v. 13, p. 1902, 2021.
• 11. Beserra, Fernando Pereira; Gushiken, Lucas Fernando Sérgio; Hussni, Maria Fernanda; Ribeiro, Victor Pena; Bonamin, Flávia; Jackson, Christopher John; Pellizzon, Cláudia Helena; Bastos, Jairo Kenupp. Artepilin C as an outstanding phenolic compound of Brazilian green propolis for disease treatment: A review on pharmacological aspects. Phytotherapy Research, v. 2020, p. 1-13, 2020.
• 12. Pereira Beserra, F.; Sérgio Gushiken, L.F.; Vieira, A.J.; Augusto Bérgamo, D.; Luísa Bérgamo, P.; Oliveira de Souza, M.; Alberto Hussni, C.; Kiomi Takahira, R.; Henrique Nóbrega, R.; Monteiro Martinez, E.R.; John Jackson, C.; Lemos de Azevedo Maia, G.; Leite Rozza, A.; Helena Pellizzon, C. From Inflammation to Cutaneous Repair: Topical Application of Lupeol Improves Skin Wound Healing in Rats by Modulating the Cytokine Levels, NF-κB, Ki-67, Growth Factor Expression, and Distribution of Collagen Fibers. International Journal of Molecular Sciences (Online), 2020, 21, 4952.
• 13. Beserra, Fernando Pereira; Vieira, Ana Júlia; Gushiken, Lucas Fernando Sérgio; De Souza, Eduardo Oliveira; Hussni, Maria Fernanda; Hussni, Carlos Alberto; Nóbrega, Rafael Henrique; Martinez, Emanuel Ricardo Monteiro; Jackson, Christopher John; De Azevedo Maia, Gabriela Lemos; Rozza, Ariane Leite; Pellizzon, Cláudia Helena. Lupeol, a Dietary Triterpene, Enhances Wound Healing in Streptozotocin-Induced Hyperglycemic Rats with Modulatory Effects on Inflammation, Oxidative Stress, and Angiogenesis. Oxidative Medicine and Cellular Longevity, v. 2019, p. 1-20, 2019.
• 14. Vieira, A.J.; Beserra, F.P.; Souza, M.C.; Totti, B.M.; Rozza, A.L. Limonene: Aroma of innovation in health and disease. Chemico-Biological Interactions, v. 283, p. 97-106, 2018.
• 15. Pereira Beserra, Fernando; Xue, Meilang; Maia, Gabriela; Leite Rozza, Ariane; Helena Pellizzon, Cláudia; Jackson, Christopher. Lupeol, a Pentacyclic Triterpene, Promotes Migration, Wound Closure, and Contractile Effect In Vitro: Possible Involvement of PI3K/Akt and p38/ERK/MAPK Pathways. Molecules, v. 23, p. 2819, 2018.
• 16. De Souza, Matheus Chiaradia; Vieira, Ana Júlia; Beserra, Fernando Pereira; Pellizzon, Cláudia Helena; Nóbrega, Rafael Henrique; Rozza, Ariane Leite. Gastroprotective effect of limonene in rats: influence on oxidative stress, inflammation, and gene expression. Phytomedicine, v. 53, p. 37-42, 2018.
• 17. Souza, M. O.; Gushiken, L. F. S.; Beserra, F. P.; Pellizzon, C. H. Evaluation of the Gastroprotective and Antioxidant Effects of Caffeine and Caffeic Acid on Ethanol Induced Gastric Ulcer. JSM hapatitis, v. 2, p. 1-5, 2017.
• 18. Gushiken, Lucas Fernando Sérgio; Hussni, Carlos Alberto; Bastos, Jairo Kenupp; Rozza, Ariane Leite; Beserra, Fernando Pereira; Vieira, Ana Júlia; Padovani, Carlos Roberto; Lemos, Marinave; Polizello Junior, Maurilio; Silva, Jonas Joaquim Mangabeira Da; Nóbrega, Rafael Henrique; Martinez, Emanuel Ricardo Monteiro; Pellizzon, Cláudia Helena. Skin Wound Healing Potential and Mechanisms of the Hydroalcoholic Extract of Leaves and Oleoresin of Copaifera langsdorffii Desf. Kuntze in Rats. Evidence-based Complementary and Alternative Medicine, v. 2017, p. 1-16, 2017.
• 19. Beserra, Fernando; De Cássia Santos, Raquel; Périco, Larissa; Rodrigues, Vinicius; De Almeida Kiguti, Luiz; Saldanha, Luiz; Pupo, André; Da Rocha, Lúcia; Dokkedal, Anne; Vilegas, Wagner; Hiruma-Lima, Clélia. Cissus sicyoides: Pharmacological Mechanisms Involved in the Anti-Inflammatory and Antidiarrheal Activities. International Journal of Molecular Sciences (Online), v. 17, p. 149, 2016.
• 20. Gushiken, Lucas F.; Beserra, Fernando P.; Rozza, Ariane L.; Bérgamo, Patricia L.; Bérgamo, Danilo A.; Pellizzon, Cláudia H. Chemical and Biological Aspects of Extracts from Medicinal Plants with Antidiabetic Effects. The Review of Diabetic Studies (Print), v. 13, p. 96-112, 2016.
• 21. Périco, Larissa Lucena; Heredia-Vieira, Silvia Cristina; Beserra, Fernando Pereira; De Cássia Dos Santos, Raquel; Weiss, Marcio Barczyszyn ; Resende, Flavia Aparecida ; Dos Santos Ramos, Matheus Aparecido; Bonifácio, Bruna Vidal; Baubá, Taís Maria; Varanda, Eliana Aparecida; De Gobbi, Juliana Irani Fratucci; Da Rocha, Lúcia Regina Machado; Vilegas, Wagner; Hiruma-Lima, Clélia Akiko. Does the gastroprotective action of a medicinal plant ensure healing effects? An integrative study of the biological effects of Serjania marginata Casar. (Sapindaceae) in rats. Journal of Ethnopharmacology, v. 172, p. 312-324, 2015.
• 22. Beserra, F. P.; Aguiar, R. W. S.; Borges, J. C. M.; Carvalho, E. E. N.; Vale, B. N. Jatropha curcas L. (Euphorbiaceae) as a new biopesticide: preliminary phytochemical analysis and larvicidal activity against Aedes aegypti (Diptera: Culicidae). Amazônia Science & Health, v. 2, p. 17-25, 2014.
• 23. Beserra, F. P.; Paiva, S. G.; Souza, S. F; Lopes, S. P. S. L.; Azevedo, D. A.; Borges, J. C. M. Perfil de utilização de medicamentos em gestantes assistidas em serviço público de saúde de Gurupi, Tocantins. Revista Cereus, v. 6, p. 1-21, 2014.
• 24. Carvalho, Katharinne Ingrid Moraes; Bonamin, Flavia; Santos, Raquel Cássia; Périco, Larissa Lucena; Beserra, Fernando Pereira; Sousa, Damião Pergentino; Filho, José Maria Barbosa; Rocha, Lucia Regina Machado; Hiruma-Lima, Clélia Akiko. Geraniol-a flavoring agent with multifunctional effects in protecting the gastric and duodenal mucosa. Naunyn-Schmiedeberg's Archives of Pharmacology, v.1, p.1-6, 2013.
• 1. Beserra, Fernando P.; Ferreira, Marcos V. De Sa; Conceição, Mariana; Rodrigues, Débora M.; Dantas, Stéfani T. Alves; Rall, Vera L. Moraes; Gaspary, Priscyla D. Marcato; Bastos, Jairo K.; Pellizzon, Cláudia H. Brazilian Green Propolis-Based Nanostructured System and its use in diabetic rats of Staphylococcus aureus resistant to methicillin (MRSA)-infected wounds. In: ASPET 2023 Annual Meeting Abstracts, 2023. ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology. p. 452.
• 2. Beserra, Fernando P.; Marincek, Andréia; Rodrigues, Debora M.; Caldas, Gabriel R.; Ferreira, Iasmin R. S.; Silva, Letícia B.; Schneider, Ayda H.; Sá, Keyla S. G.; Gaspary, Priscyla D. M.; Bastos, Jairo K. Brazilian Green Propolis-Based Nanostructured System: Development, Characterization and its role in the Modulation of Cytokines in In Vitro and In Vivo Experimental Models. In: Experimental Biology, 2022, Philladelphia, 2022, FASEB JOURNAL, v. 36, p. 1, 2022.
• 3. Beserra, F.P.; Rozza, A. L.; Maia, G. L. A.; Vieira, A. J.; Gushiken, L. F. S.; Xue, M.; Jackson, C.; Pellizzon, C. H.. Lupeol, a dietary triterpene, inhibits inflammation and promotes migration and angiogenesis via Pi3k/Akt and Mapk pathways. In: Symposium on Advanced Wound Care, 2018, Charlotte. Oral & Poster Abstracts SAWC/SPRING, 2018.
• 4. Beserra, F. P.; Vieira, A. J.; Souza, E. O.; Gushiken, L. F. S.; Hussni, C. A.; Maia, G. L. A.; Rozza, A. L.; Pellizzon, C. H. Lupeol, a triterpene isolated of Bowdichia virgilioides Kunth. (Steam bark) accelerates cutaneous wound healing in diabetic rats. In: 21st International Congress of Phytopharm, 2017, Graz, Austria. Reviews on Clinical Pharmacology and Drug Therapy. Graz, 2017. v. 15.
• 5. Beserra, F. P.; Maia, G. L. A.; Rozza, A. L.; Pellizzon, C. H.; Xue, M.; Jackson, C.. In vitro wound healing potential of the triterpene Lupeol isolated from the steam bark of Bowdichia virgilioides Kunth. In: 21st International Congress of Phytopharm, 2017, Graz, Austria. Reviews on Clinical Pharmacology and Drug Therapy. Graz, 2017. v. 15.
• 6. Beserra, F. P.; Bergamo, D. A.; Bergamo, P. L.; Vieira, A. J.; Hussni, C. A.; Maia, G. L. A.; Rozza, A. L.; Pellizzon, C. H. Modulation of pro- and anti-inflammatory cytokines contribute to the healing effect of the triterpene lupeol in cutaneous wounds in rats. In: 14th International Congress of Immunology, 2016, Melbourne. Abstract book of 14th ICI, 2016.